| Full name: zinc finger protein 14 | Alias Symbol: KOX6|GIOT-4 | ||
| Type: protein-coding gene | Cytoband: 19p13.11 | ||
| Entrez ID: 7561 | HGNC ID: HGNC:12924 | Ensembl Gene: ENSG00000105708 | OMIM ID: 194556 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of ZNF14:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ZNF14 | 7561 | 219854_at | 0.0536 | 0.9363 | |
| GSE20347 | ZNF14 | 7561 | 219854_at | -0.0457 | 0.8655 | |
| GSE23400 | ZNF14 | 7561 | 219854_at | -0.0947 | 0.0563 | |
| GSE26886 | ZNF14 | 7561 | 219854_at | 0.7216 | 0.0195 | |
| GSE29001 | ZNF14 | 7561 | 219854_at | -0.1110 | 0.7885 | |
| GSE38129 | ZNF14 | 7561 | 219854_at | -0.1973 | 0.2695 | |
| GSE45670 | ZNF14 | 7561 | 219854_at | -0.0595 | 0.8082 | |
| GSE53622 | ZNF14 | 7561 | 100525 | -0.4333 | 0.0000 | |
| GSE53624 | ZNF14 | 7561 | 100525 | -0.3769 | 0.0000 | |
| GSE63941 | ZNF14 | 7561 | 219854_at | -0.8294 | 0.2746 | |
| GSE77861 | ZNF14 | 7561 | 219854_at | -0.1152 | 0.7524 | |
| GSE97050 | ZNF14 | 7561 | A_23_P101811 | -0.2156 | 0.3094 | |
| SRP007169 | ZNF14 | 7561 | RNAseq | 0.5497 | 0.3591 | |
| SRP008496 | ZNF14 | 7561 | RNAseq | 1.2225 | 0.0129 | |
| SRP064894 | ZNF14 | 7561 | RNAseq | -0.3800 | 0.0387 | |
| SRP133303 | ZNF14 | 7561 | RNAseq | -0.2604 | 0.0191 | |
| SRP159526 | ZNF14 | 7561 | RNAseq | -0.3435 | 0.5437 | |
| SRP193095 | ZNF14 | 7561 | RNAseq | -0.3652 | 0.0109 | |
| SRP219564 | ZNF14 | 7561 | RNAseq | -0.3716 | 0.2872 | |
| TCGA | ZNF14 | 7561 | RNAseq | -0.3510 | 0.0050 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by ZNF14 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ZNF14:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ZNF14 | 7561 | 4 | 5 | 21 | |
| GSE20123 | ZNF14 | 7561 | 3 | 3 | 24 | |
| GSE43470 | ZNF14 | 7561 | 2 | 5 | 36 | |
| GSE46452 | ZNF14 | 7561 | 47 | 1 | 11 | |
| GSE47630 | ZNF14 | 7561 | 5 | 8 | 27 | |
| GSE54993 | ZNF14 | 7561 | 16 | 4 | 50 | |
| GSE54994 | ZNF14 | 7561 | 6 | 13 | 34 | |
| GSE60625 | ZNF14 | 7561 | 9 | 0 | 2 | |
| GSE74703 | ZNF14 | 7561 | 2 | 3 | 31 | |
| GSE74704 | ZNF14 | 7561 | 0 | 3 | 17 | |
| TCGA | ZNF14 | 7561 | 16 | 10 | 70 |
Total number of gains: 110; Total number of losses: 55; Total Number of normals: 323.
Somatic mutations of ZNF14:
Generating mutation plots.
Highly correlated genes for ZNF14:
Showing top 20/29 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ZNF14 | RAB40B | 0.838519 | 3 | 0 | 3 |
| ZNF14 | CCDC122 | 0.705747 | 3 | 0 | 3 |
| ZNF14 | USP27X | 0.687203 | 3 | 0 | 3 |
| ZNF14 | RWDD3 | 0.686375 | 3 | 0 | 3 |
| ZNF14 | KRT77 | 0.659392 | 3 | 0 | 3 |
| ZNF14 | CUZD1 | 0.653658 | 3 | 0 | 3 |
| ZNF14 | PGAP3 | 0.638012 | 3 | 0 | 3 |
| ZNF14 | ZNF682 | 0.619126 | 9 | 0 | 6 |
| ZNF14 | TBC1D7 | 0.608843 | 3 | 0 | 3 |
| ZNF14 | ZNF232 | 0.604841 | 4 | 0 | 4 |
| ZNF14 | TATDN3 | 0.602999 | 4 | 0 | 3 |
| ZNF14 | ZNF30 | 0.599541 | 5 | 0 | 4 |
| ZNF14 | ZADH2 | 0.598377 | 4 | 0 | 3 |
| ZNF14 | BEND7 | 0.589698 | 4 | 0 | 3 |
| ZNF14 | ZNF738 | 0.589364 | 6 | 0 | 3 |
| ZNF14 | ZNF440 | 0.582774 | 4 | 0 | 3 |
| ZNF14 | KAT8 | 0.563524 | 4 | 0 | 3 |
| ZNF14 | ZNF443 | 0.563123 | 7 | 0 | 4 |
| ZNF14 | ZNF559 | 0.56259 | 5 | 0 | 3 |
| ZNF14 | ZSCAN32 | 0.554817 | 3 | 0 | 3 |
For details and further investigation, click here
