| Full name: zinc binding alcohol dehydrogenase domain containing 2 | Alias Symbol: MGC45594 | ||
| Type: protein-coding gene | Cytoband: 18q22.3 | ||
| Entrez ID: 284273 | HGNC ID: HGNC:28697 | Ensembl Gene: ENSG00000180011 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of ZADH2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ZADH2 | 284273 | 1554239_s_at | -0.4501 | 0.3917 | |
| GSE26886 | ZADH2 | 284273 | 1554239_s_at | -0.7593 | 0.0014 | |
| GSE45670 | ZADH2 | 284273 | 227049_at | -0.4477 | 0.0321 | |
| GSE53622 | ZADH2 | 284273 | 18088 | -0.8203 | 0.0000 | |
| GSE53624 | ZADH2 | 284273 | 18088 | -0.5150 | 0.0000 | |
| GSE63941 | ZADH2 | 284273 | 1554239_s_at | -0.2624 | 0.6318 | |
| GSE77861 | ZADH2 | 284273 | 1554239_s_at | -0.0598 | 0.7649 | |
| GSE97050 | ZADH2 | 284273 | A_24_P22746 | -0.1939 | 0.3530 | |
| SRP007169 | ZADH2 | 284273 | RNAseq | -0.9319 | 0.0087 | |
| SRP008496 | ZADH2 | 284273 | RNAseq | -0.7499 | 0.0079 | |
| SRP064894 | ZADH2 | 284273 | RNAseq | -0.4283 | 0.0083 | |
| SRP133303 | ZADH2 | 284273 | RNAseq | -0.5408 | 0.0000 | |
| SRP159526 | ZADH2 | 284273 | RNAseq | -0.2962 | 0.1463 | |
| SRP193095 | ZADH2 | 284273 | RNAseq | -0.4280 | 0.0001 | |
| SRP219564 | ZADH2 | 284273 | RNAseq | -0.5302 | 0.0650 | |
| TCGA | ZADH2 | 284273 | RNAseq | -0.1906 | 0.0005 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by ZADH2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ZADH2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ZADH2 | 284273 | 0 | 11 | 19 | |
| GSE20123 | ZADH2 | 284273 | 0 | 11 | 19 | |
| GSE43470 | ZADH2 | 284273 | 0 | 8 | 35 | |
| GSE46452 | ZADH2 | 284273 | 1 | 26 | 32 | |
| GSE47630 | ZADH2 | 284273 | 5 | 22 | 13 | |
| GSE54993 | ZADH2 | 284273 | 9 | 0 | 61 | |
| GSE54994 | ZADH2 | 284273 | 1 | 18 | 34 | |
| GSE60625 | ZADH2 | 284273 | 0 | 4 | 7 | |
| GSE74703 | ZADH2 | 284273 | 0 | 7 | 29 | |
| GSE74704 | ZADH2 | 284273 | 0 | 9 | 11 | |
| TCGA | ZADH2 | 284273 | 7 | 47 | 42 |
Total number of gains: 23; Total number of losses: 163; Total Number of normals: 302.
Somatic mutations of ZADH2:
Generating mutation plots.
Highly correlated genes for ZADH2:
Showing top 20/142 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ZADH2 | SETDB2 | 0.76166 | 3 | 0 | 3 |
| ZADH2 | RPS6 | 0.690492 | 3 | 0 | 3 |
| ZADH2 | BTBD10 | 0.676444 | 3 | 0 | 3 |
| ZADH2 | BCDIN3D | 0.668467 | 3 | 0 | 3 |
| ZADH2 | DEPTOR | 0.665927 | 3 | 0 | 3 |
| ZADH2 | OARD1 | 0.660129 | 4 | 0 | 3 |
| ZADH2 | KDM4C | 0.654809 | 5 | 0 | 5 |
| ZADH2 | RNF20 | 0.646407 | 3 | 0 | 3 |
| ZADH2 | RP2 | 0.642296 | 3 | 0 | 3 |
| ZADH2 | HECTD1 | 0.641508 | 3 | 0 | 3 |
| ZADH2 | TJP2 | 0.64115 | 5 | 0 | 4 |
| ZADH2 | FBXO34 | 0.641062 | 4 | 0 | 3 |
| ZADH2 | SNX24 | 0.637723 | 4 | 0 | 4 |
| ZADH2 | JADE1 | 0.634422 | 4 | 0 | 4 |
| ZADH2 | UBXN6 | 0.631633 | 3 | 0 | 3 |
| ZADH2 | NICN1 | 0.630981 | 4 | 0 | 3 |
| ZADH2 | AP4B1 | 0.629241 | 5 | 0 | 4 |
| ZADH2 | HEIH | 0.623424 | 4 | 0 | 3 |
| ZADH2 | ATP8A1 | 0.62224 | 4 | 0 | 3 |
| ZADH2 | SPRY3 | 0.617325 | 3 | 0 | 3 |
For details and further investigation, click here
