| Full name: keratin 77 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 12q13.13 | ||
| Entrez ID: 374454 | HGNC ID: HGNC:20411 | Ensembl Gene: ENSG00000189182 | OMIM ID: 611158 |
| Drug and gene relationship at DGIdb | |||
Expression of KRT77:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | KRT77 | 374454 | 237120_at | -0.0646 | 0.8520 | |
| GSE26886 | KRT77 | 374454 | 237120_at | -0.0508 | 0.8636 | |
| GSE45670 | KRT77 | 374454 | 237120_at | 0.2000 | 0.6061 | |
| GSE53622 | KRT77 | 374454 | 14477 | -0.2493 | 0.0034 | |
| GSE53624 | KRT77 | 374454 | 14477 | -0.2402 | 0.0049 | |
| GSE63941 | KRT77 | 374454 | 237120_at | -0.0776 | 0.6462 | |
| GSE77861 | KRT77 | 374454 | 237120_at | 0.0860 | 0.5083 | |
| GSE97050 | KRT77 | 374454 | A_33_P3315288 | -0.2201 | 0.4511 | |
| TCGA | KRT77 | 374454 | RNAseq | 1.8828 | 0.0177 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by KRT77 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of KRT77:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | KRT77 | 374454 | 8 | 1 | 21 | |
| GSE20123 | KRT77 | 374454 | 8 | 1 | 21 | |
| GSE43470 | KRT77 | 374454 | 3 | 0 | 40 | |
| GSE46452 | KRT77 | 374454 | 7 | 1 | 51 | |
| GSE47630 | KRT77 | 374454 | 10 | 2 | 28 | |
| GSE54993 | KRT77 | 374454 | 0 | 5 | 65 | |
| GSE54994 | KRT77 | 374454 | 5 | 1 | 47 | |
| GSE60625 | KRT77 | 374454 | 0 | 0 | 11 | |
| GSE74703 | KRT77 | 374454 | 3 | 0 | 33 | |
| GSE74704 | KRT77 | 374454 | 5 | 1 | 14 | |
| TCGA | KRT77 | 374454 | 13 | 11 | 72 |
Total number of gains: 62; Total number of losses: 23; Total Number of normals: 403.
Somatic mutations of KRT77:
Generating mutation plots.
Highly correlated genes for KRT77:
Showing top 20/117 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| KRT77 | GDF7 | 0.819146 | 3 | 0 | 3 |
| KRT77 | PRSS38 | 0.809269 | 3 | 0 | 3 |
| KRT77 | YY2 | 0.809103 | 3 | 0 | 3 |
| KRT77 | KCNJ13 | 0.807145 | 3 | 0 | 3 |
| KRT77 | OTOG | 0.802718 | 3 | 0 | 3 |
| KRT77 | KRTAP6-1 | 0.790425 | 3 | 0 | 3 |
| KRT77 | PAX6 | 0.77864 | 3 | 0 | 3 |
| KRT77 | INSC | 0.775616 | 3 | 0 | 3 |
| KRT77 | OR10AD1 | 0.77458 | 3 | 0 | 3 |
| KRT77 | TSSK3 | 0.773076 | 3 | 0 | 3 |
| KRT77 | ESPNL | 0.770801 | 3 | 0 | 3 |
| KRT77 | NOBOX | 0.769279 | 3 | 0 | 3 |
| KRT77 | KCNQ4 | 0.768223 | 3 | 0 | 3 |
| KRT77 | OR2B11 | 0.766771 | 3 | 0 | 3 |
| KRT77 | TXNDC2 | 0.763349 | 3 | 0 | 3 |
| KRT77 | PROCA1 | 0.751529 | 3 | 0 | 3 |
| KRT77 | SPN | 0.751183 | 3 | 0 | 3 |
| KRT77 | CCDC81 | 0.748052 | 3 | 0 | 3 |
| KRT77 | OR1F1 | 0.747223 | 3 | 0 | 3 |
| KRT77 | RNF180 | 0.743275 | 3 | 0 | 3 |
For details and further investigation, click here
