| Full name: RAB40B, member RAS oncogene family | Alias Symbol: SEC4L|RAR | ||
| Type: protein-coding gene | Cytoband: 17q25.3 | ||
| Entrez ID: 10966 | HGNC ID: HGNC:18284 | Ensembl Gene: ENSG00000141542 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of RAB40B:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | RAB40B | 10966 | 204547_at | 0.2947 | 0.8162 | |
| GSE20347 | RAB40B | 10966 | 204547_at | 0.4258 | 0.0650 | |
| GSE23400 | RAB40B | 10966 | 204547_at | 0.4126 | 0.0009 | |
| GSE26886 | RAB40B | 10966 | 204547_at | 1.1254 | 0.0001 | |
| GSE29001 | RAB40B | 10966 | 204547_at | 0.1456 | 0.7754 | |
| GSE38129 | RAB40B | 10966 | 204547_at | 0.3840 | 0.0505 | |
| GSE45670 | RAB40B | 10966 | 204547_at | -0.2225 | 0.5667 | |
| GSE53622 | RAB40B | 10966 | 37006 | -0.1649 | 0.0440 | |
| GSE53624 | RAB40B | 10966 | 37006 | -0.9421 | 0.0000 | |
| GSE63941 | RAB40B | 10966 | 204547_at | -1.0085 | 0.2780 | |
| GSE77861 | RAB40B | 10966 | 217597_x_at | -0.1568 | 0.4493 | |
| GSE97050 | RAB40B | 10966 | A_23_P129801 | -0.1531 | 0.5540 | |
| SRP007169 | RAB40B | 10966 | RNAseq | 0.7404 | 0.2269 | |
| SRP008496 | RAB40B | 10966 | RNAseq | 0.4548 | 0.2622 | |
| SRP064894 | RAB40B | 10966 | RNAseq | -0.0603 | 0.7897 | |
| SRP133303 | RAB40B | 10966 | RNAseq | -0.0851 | 0.6654 | |
| SRP159526 | RAB40B | 10966 | RNAseq | 0.6991 | 0.0047 | |
| SRP193095 | RAB40B | 10966 | RNAseq | -0.1089 | 0.5114 | |
| SRP219564 | RAB40B | 10966 | RNAseq | -0.2385 | 0.5813 | |
| TCGA | RAB40B | 10966 | RNAseq | -0.0775 | 0.4001 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by RAB40B expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of RAB40B:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | RAB40B | 10966 | 4 | 5 | 21 | |
| GSE20123 | RAB40B | 10966 | 4 | 5 | 21 | |
| GSE43470 | RAB40B | 10966 | 3 | 5 | 35 | |
| GSE46452 | RAB40B | 10966 | 34 | 0 | 25 | |
| GSE47630 | RAB40B | 10966 | 9 | 2 | 29 | |
| GSE54993 | RAB40B | 10966 | 2 | 5 | 63 | |
| GSE54994 | RAB40B | 10966 | 10 | 6 | 37 | |
| GSE60625 | RAB40B | 10966 | 6 | 0 | 5 | |
| GSE74703 | RAB40B | 10966 | 3 | 3 | 30 | |
| GSE74704 | RAB40B | 10966 | 4 | 4 | 12 | |
| TCGA | RAB40B | 10966 | 25 | 15 | 56 |
Total number of gains: 104; Total number of losses: 50; Total Number of normals: 334.
Somatic mutations of RAB40B:
Generating mutation plots.
Highly correlated genes for RAB40B:
Showing top 20/125 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| RAB40B | ZNF14 | 0.838519 | 3 | 0 | 3 |
| RAB40B | ABCA2 | 0.787721 | 3 | 0 | 3 |
| RAB40B | TDGF1 | 0.760804 | 3 | 0 | 3 |
| RAB40B | KIRREL2 | 0.759046 | 3 | 0 | 3 |
| RAB40B | POLL | 0.750457 | 3 | 0 | 3 |
| RAB40B | TTC32 | 0.750361 | 3 | 0 | 3 |
| RAB40B | CCDC130 | 0.744919 | 3 | 0 | 3 |
| RAB40B | MAP7D2 | 0.740883 | 3 | 0 | 3 |
| RAB40B | MIIP | 0.721154 | 3 | 0 | 3 |
| RAB40B | KLHL14 | 0.71463 | 3 | 0 | 3 |
| RAB40B | SRRM3 | 0.712601 | 3 | 0 | 3 |
| RAB40B | ITGA2B | 0.710199 | 4 | 0 | 3 |
| RAB40B | KRTAP6-1 | 0.708158 | 3 | 0 | 3 |
| RAB40B | COPS7B | 0.707442 | 3 | 0 | 3 |
| RAB40B | BRD1 | 0.707242 | 4 | 0 | 3 |
| RAB40B | SLC39A5 | 0.700695 | 4 | 0 | 4 |
| RAB40B | OR13G1 | 0.690307 | 3 | 0 | 3 |
| RAB40B | S1PR4 | 0.688098 | 3 | 0 | 3 |
| RAB40B | PHOSPHO1 | 0.686085 | 4 | 0 | 4 |
| RAB40B | PTPRR | 0.685405 | 3 | 0 | 3 |
For details and further investigation, click here
