| Full name: zinc finger protein 443 | Alias Symbol: ZK1 | ||
| Type: protein-coding gene | Cytoband: 19p13.2 | ||
| Entrez ID: 10224 | HGNC ID: HGNC:20878 | Ensembl Gene: ENSG00000180855 | OMIM ID: 606697 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of ZNF443:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ZNF443 | 10224 | 205928_at | 0.0472 | 0.9572 | |
| GSE20347 | ZNF443 | 10224 | 205928_at | 0.0557 | 0.6865 | |
| GSE23400 | ZNF443 | 10224 | 205928_at | 0.1268 | 0.0058 | |
| GSE26886 | ZNF443 | 10224 | 205928_at | 0.0045 | 0.9918 | |
| GSE29001 | ZNF443 | 10224 | 205928_at | -0.0110 | 0.9785 | |
| GSE38129 | ZNF443 | 10224 | 205928_at | -0.0581 | 0.6125 | |
| GSE45670 | ZNF443 | 10224 | 205928_at | -0.0074 | 0.9735 | |
| GSE53622 | ZNF443 | 10224 | 91163 | -0.5163 | 0.0000 | |
| GSE53624 | ZNF443 | 10224 | 91163 | -0.6817 | 0.0000 | |
| GSE63941 | ZNF443 | 10224 | 205928_at | -0.6526 | 0.5476 | |
| GSE77861 | ZNF443 | 10224 | 205928_at | -0.0791 | 0.8310 | |
| GSE97050 | ZNF443 | 10224 | A_23_P67278 | -0.2408 | 0.2991 | |
| SRP007169 | ZNF443 | 10224 | RNAseq | 0.2253 | 0.7363 | |
| SRP064894 | ZNF443 | 10224 | RNAseq | -0.0959 | 0.7497 | |
| SRP133303 | ZNF443 | 10224 | RNAseq | -0.0035 | 0.9906 | |
| SRP159526 | ZNF443 | 10224 | RNAseq | -0.1563 | 0.6860 | |
| SRP193095 | ZNF443 | 10224 | RNAseq | -0.4689 | 0.0002 | |
| SRP219564 | ZNF443 | 10224 | RNAseq | -0.1863 | 0.7349 | |
| TCGA | ZNF443 | 10224 | RNAseq | -0.2310 | 0.1407 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by ZNF443 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ZNF443:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ZNF443 | 10224 | 4 | 2 | 24 | |
| GSE20123 | ZNF443 | 10224 | 3 | 1 | 26 | |
| GSE43470 | ZNF443 | 10224 | 2 | 6 | 35 | |
| GSE46452 | ZNF443 | 10224 | 47 | 1 | 11 | |
| GSE47630 | ZNF443 | 10224 | 4 | 7 | 29 | |
| GSE54993 | ZNF443 | 10224 | 16 | 3 | 51 | |
| GSE54994 | ZNF443 | 10224 | 6 | 13 | 34 | |
| GSE60625 | ZNF443 | 10224 | 9 | 0 | 2 | |
| GSE74703 | ZNF443 | 10224 | 2 | 4 | 30 | |
| GSE74704 | ZNF443 | 10224 | 0 | 1 | 19 | |
| TCGA | ZNF443 | 10224 | 15 | 14 | 67 |
Total number of gains: 108; Total number of losses: 52; Total Number of normals: 328.
Somatic mutations of ZNF443:
Generating mutation plots.
Highly correlated genes for ZNF443:
Showing top 20/111 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ZNF443 | SHPRH | 0.706177 | 5 | 0 | 4 |
| ZNF443 | C4orf3 | 0.701952 | 3 | 0 | 3 |
| ZNF443 | SH3BGRL2 | 0.686517 | 3 | 0 | 3 |
| ZNF443 | UBL3 | 0.657687 | 3 | 0 | 3 |
| ZNF443 | LINC00865 | 0.656973 | 3 | 0 | 3 |
| ZNF443 | ZNF708 | 0.656932 | 5 | 0 | 3 |
| ZNF443 | JADE3 | 0.650504 | 3 | 0 | 3 |
| ZNF443 | FAM76B | 0.646202 | 4 | 0 | 3 |
| ZNF443 | LUC7L2 | 0.641825 | 3 | 0 | 3 |
| ZNF443 | ZNF564 | 0.637887 | 5 | 0 | 5 |
| ZNF443 | SYNJ1 | 0.6263 | 3 | 0 | 3 |
| ZNF443 | TMPRSS2 | 0.619195 | 3 | 0 | 3 |
| ZNF443 | SPIN3 | 0.619036 | 3 | 0 | 3 |
| ZNF443 | ZNF738 | 0.616133 | 7 | 0 | 5 |
| ZNF443 | SIM2 | 0.612683 | 3 | 0 | 3 |
| ZNF443 | LPIN2 | 0.602419 | 3 | 0 | 3 |
| ZNF443 | RNF141 | 0.602033 | 3 | 0 | 3 |
| ZNF443 | CRISP2 | 0.601274 | 3 | 0 | 3 |
| ZNF443 | CIPC | 0.601237 | 3 | 0 | 3 |
| ZNF443 | SLC10A5 | 0.595338 | 3 | 0 | 3 |
For details and further investigation, click here
