| Full name: post-GPI attachment to proteins 3 | Alias Symbol: MGC9753|CAB2|PP1498|PER1 | ||
| Type: protein-coding gene | Cytoband: 17q21.2 | ||
| Entrez ID: 93210 | HGNC ID: HGNC:23719 | Ensembl Gene: ENSG00000161395 | OMIM ID: 611801 |
| Drug and gene relationship at DGIdb | |||
Expression of PGAP3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PGAP3 | 93210 | 55616_at | -0.1746 | 0.8036 | |
| GSE20347 | PGAP3 | 93210 | 55616_at | -0.7545 | 0.0000 | |
| GSE23400 | PGAP3 | 93210 | 55616_at | -0.3060 | 0.0021 | |
| GSE26886 | PGAP3 | 93210 | 55616_at | -0.4993 | 0.0141 | |
| GSE29001 | PGAP3 | 93210 | 55616_at | -0.8052 | 0.0014 | |
| GSE38129 | PGAP3 | 93210 | 55616_at | -0.5512 | 0.0001 | |
| GSE45670 | PGAP3 | 93210 | 55616_at | -0.4974 | 0.0166 | |
| GSE53622 | PGAP3 | 93210 | 135783 | -0.5841 | 0.0000 | |
| GSE53624 | PGAP3 | 93210 | 135783 | -1.0369 | 0.0000 | |
| GSE63941 | PGAP3 | 93210 | 55616_at | -0.1718 | 0.8926 | |
| GSE77861 | PGAP3 | 93210 | 55616_at | -0.4709 | 0.0937 | |
| GSE97050 | PGAP3 | 93210 | A_24_P275828 | -0.1802 | 0.3389 | |
| SRP064894 | PGAP3 | 93210 | RNAseq | -0.3487 | 0.1977 | |
| SRP133303 | PGAP3 | 93210 | RNAseq | -0.9850 | 0.0000 | |
| SRP159526 | PGAP3 | 93210 | RNAseq | -0.8916 | 0.0012 | |
| SRP193095 | PGAP3 | 93210 | RNAseq | -0.9691 | 0.0000 | |
| SRP219564 | PGAP3 | 93210 | RNAseq | -0.1360 | 0.7676 | |
| TCGA | PGAP3 | 93210 | RNAseq | -0.1549 | 0.0304 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by PGAP3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PGAP3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PGAP3 | 93210 | 9 | 1 | 20 | |
| GSE20123 | PGAP3 | 93210 | 9 | 1 | 20 | |
| GSE43470 | PGAP3 | 93210 | 1 | 1 | 41 | |
| GSE46452 | PGAP3 | 93210 | 34 | 0 | 25 | |
| GSE47630 | PGAP3 | 93210 | 8 | 1 | 31 | |
| GSE54993 | PGAP3 | 93210 | 3 | 4 | 63 | |
| GSE54994 | PGAP3 | 93210 | 9 | 5 | 39 | |
| GSE60625 | PGAP3 | 93210 | 4 | 0 | 7 | |
| GSE74703 | PGAP3 | 93210 | 1 | 0 | 35 | |
| GSE74704 | PGAP3 | 93210 | 5 | 1 | 14 | |
| TCGA | PGAP3 | 93210 | 23 | 8 | 65 |
Total number of gains: 106; Total number of losses: 22; Total Number of normals: 360.
Somatic mutations of PGAP3:
Generating mutation plots.
Highly correlated genes for PGAP3:
Showing top 20/1161 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PGAP3 | ERBB2 | 0.803736 | 13 | 0 | 13 |
| PGAP3 | NCCRP1 | 0.772014 | 3 | 0 | 3 |
| PGAP3 | TPRN | 0.760892 | 6 | 0 | 6 |
| PGAP3 | CYP3A7 | 0.735803 | 3 | 0 | 3 |
| PGAP3 | VSIG10L | 0.722381 | 6 | 0 | 6 |
| PGAP3 | IQCF1 | 0.721505 | 4 | 0 | 4 |
| PGAP3 | MFSD2B | 0.7096 | 3 | 0 | 3 |
| PGAP3 | KIAA1671 | 0.706538 | 4 | 0 | 4 |
| PGAP3 | FAM3B | 0.705695 | 7 | 0 | 7 |
| PGAP3 | EPS8L2 | 0.704718 | 11 | 0 | 9 |
| PGAP3 | LRRC26 | 0.699858 | 3 | 0 | 3 |
| PGAP3 | SLC9A9 | 0.698391 | 5 | 0 | 5 |
| PGAP3 | PPL | 0.696089 | 9 | 0 | 9 |
| PGAP3 | KRTAP20-1 | 0.691108 | 3 | 0 | 3 |
| PGAP3 | AIF1L | 0.68979 | 6 | 0 | 6 |
| PGAP3 | MORN3 | 0.68865 | 4 | 0 | 4 |
| PGAP3 | ERBB3 | 0.687687 | 11 | 0 | 10 |
| PGAP3 | MUC22 | 0.686809 | 3 | 0 | 3 |
| PGAP3 | NANOS2 | 0.68413 | 4 | 0 | 4 |
| PGAP3 | EPS8L1 | 0.683142 | 11 | 0 | 9 |
For details and further investigation, click here
