| Full name: lysine acetyltransferase 8 | Alias Symbol: MOF|FLJ14040|hMOF|ZC2HC8 | ||
| Type: protein-coding gene | Cytoband: 16p11.2 | ||
| Entrez ID: 84148 | HGNC ID: HGNC:17933 | Ensembl Gene: ENSG00000103510 | OMIM ID: 609912 |
| Related drugs: CHEMBL1215739... [more] | |||
Expression of KAT8:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | KAT8 | 84148 | 221820_s_at | -0.0547 | 0.9352 | |
| GSE20347 | KAT8 | 84148 | 221820_s_at | 0.0667 | 0.7014 | |
| GSE23400 | KAT8 | 84148 | 214885_at | -0.1168 | 0.0096 | |
| GSE26886 | KAT8 | 84148 | 221820_s_at | 0.8809 | 0.0000 | |
| GSE29001 | KAT8 | 84148 | 221820_s_at | 0.2457 | 0.3815 | |
| GSE38129 | KAT8 | 84148 | 221820_s_at | -0.0220 | 0.8645 | |
| GSE45670 | KAT8 | 84148 | 221820_s_at | -0.0806 | 0.5942 | |
| GSE53622 | KAT8 | 84148 | 82619 | 0.0349 | 0.5819 | |
| GSE53624 | KAT8 | 84148 | 82619 | 0.1370 | 0.0053 | |
| GSE63941 | KAT8 | 84148 | 221820_s_at | 1.0166 | 0.0384 | |
| GSE77861 | KAT8 | 84148 | 221820_s_at | 0.0783 | 0.7805 | |
| GSE97050 | KAT8 | 84148 | A_33_P3287745 | -0.2517 | 0.3590 | |
| SRP007169 | KAT8 | 84148 | RNAseq | 0.2013 | 0.5982 | |
| SRP008496 | KAT8 | 84148 | RNAseq | -0.0807 | 0.7437 | |
| SRP064894 | KAT8 | 84148 | RNAseq | 0.1510 | 0.4696 | |
| SRP133303 | KAT8 | 84148 | RNAseq | 0.0267 | 0.8614 | |
| SRP159526 | KAT8 | 84148 | RNAseq | 0.2726 | 0.2500 | |
| SRP193095 | KAT8 | 84148 | RNAseq | 0.1384 | 0.1096 | |
| SRP219564 | KAT8 | 84148 | RNAseq | 0.2455 | 0.3446 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by KAT8 expression:
 |  |
| GSE53622 | GSE53624 |
Note: Click image to view full size file.
Copy number change of KAT8:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | KAT8 | 84148 | 4 | 5 | 21 | |
| GSE20123 | KAT8 | 84148 | 4 | 4 | 22 | |
| GSE43470 | KAT8 | 84148 | 3 | 3 | 37 | |
| GSE46452 | KAT8 | 84148 | 38 | 1 | 20 | |
| GSE47630 | KAT8 | 84148 | 11 | 7 | 22 | |
| GSE54993 | KAT8 | 84148 | 2 | 5 | 63 | |
| GSE54994 | KAT8 | 84148 | 5 | 9 | 39 | |
| GSE60625 | KAT8 | 84148 | 4 | 0 | 7 | |
| GSE74703 | KAT8 | 84148 | 3 | 2 | 31 | |
| GSE74704 | KAT8 | 84148 | 3 | 2 | 15 | |
| TCGA | KAT8 | 84148 | 20 | 10 | 66 |
Total number of gains: 97; Total number of losses: 48; Total Number of normals: 343.
Somatic mutations of KAT8:
Generating mutation plots.
Highly correlated genes for KAT8:
Showing top 20/83 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| KAT8 | C7orf26 | 0.76403 | 3 | 0 | 3 |
| KAT8 | FOXJ1 | 0.735663 | 3 | 0 | 3 |
| KAT8 | GTF2IRD2 | 0.732839 | 3 | 0 | 3 |
| KAT8 | WDR72 | 0.711031 | 3 | 0 | 3 |
| KAT8 | LAMA5 | 0.67236 | 3 | 0 | 3 |
| KAT8 | TOE1 | 0.672187 | 4 | 0 | 3 |
| KAT8 | LRFN2 | 0.669498 | 3 | 0 | 3 |
| KAT8 | HSPBAP1 | 0.664089 | 4 | 0 | 3 |
| KAT8 | TMEM198 | 0.662815 | 3 | 0 | 3 |
| KAT8 | FBXL15 | 0.660612 | 4 | 0 | 3 |
| KAT8 | CLN3 | 0.653835 | 6 | 0 | 6 |
| KAT8 | TP53BP1 | 0.652644 | 3 | 0 | 3 |
| KAT8 | TNNC2 | 0.649305 | 3 | 0 | 3 |
| KAT8 | NUBP1 | 0.648994 | 6 | 0 | 5 |
| KAT8 | DCTPP1 | 0.648006 | 5 | 0 | 5 |
| KAT8 | ARFIP2 | 0.643544 | 5 | 0 | 4 |
| KAT8 | KXD1 | 0.64094 | 3 | 0 | 3 |
| KAT8 | CORT | 0.63263 | 3 | 0 | 3 |
| KAT8 | RPS6KL1 | 0.631779 | 3 | 0 | 3 |
| KAT8 | NMRAL1 | 0.631675 | 3 | 0 | 3 |
For details and further investigation, click here
