ZNF493

 

Full name: zinc finger protein 493 Alias Symbol: FLJ36504
Type: protein-coding gene Cytoband: 19p12
Entrez ID: 284443 HGNC ID: HGNC:23708 Ensembl Gene: ENSG00000196268 OMIM ID: 
Drug and gene relationship at DGIdb

 

Expression of ZNF493:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 ZNF493 284443 1558486_at -0.5228 0.5441
GSE20347 ZNF493 284443 211064_at -0.2880 0.0661
GSE23400 ZNF493 284443 211064_at -0.1245 0.0009
GSE26886 ZNF493 284443 240155_x_at -1.6353 0.0016
GSE29001 ZNF493 284443 211064_at -0.8187 0.0104
GSE38129 ZNF493 284443 211064_at -0.3571 0.0057
GSE45670 ZNF493 284443 240155_x_at -0.9385 0.0040
GSE53622 ZNF493 284443 5357 -0.5417 0.0000
GSE53624 ZNF493 284443 5357 -0.5045 0.0000
GSE63941 ZNF493 284443 1558486_at -0.0699 0.9601
GSE77861 ZNF493 284443 240155_x_at -0.5786 0.1578
GSE97050 ZNF493 284443 A_24_P332862 -0.1806 0.5852
SRP007169 ZNF493 284443 RNAseq -1.6087 0.0005
SRP008496 ZNF493 284443 RNAseq -1.3054 0.0001
SRP064894 ZNF493 284443 RNAseq -0.7708 0.0017
SRP133303 ZNF493 284443 RNAseq -0.4833 0.0205
SRP159526 ZNF493 284443 RNAseq -0.7495 0.1467
SRP193095 ZNF493 284443 RNAseq -0.8342 0.0000
SRP219564 ZNF493 284443 RNAseq -0.5717 0.1753
TCGA ZNF493 284443 RNAseq -0.9923 0.0000

Upregulated datasets: 0; Downregulated datasets: 3.  


 

Survival by ZNF493 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  


Copy number change of ZNF493:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 ZNF493 284443 4 5 21
GSE20123 ZNF493 284443 4 3 23
GSE43470 ZNF493 284443 2 6 35
GSE46452 ZNF493 284443 47 1 11
GSE47630 ZNF493 284443 7 7 26
GSE54993 ZNF493 284443 17 3 50
GSE54994 ZNF493 284443 6 13 34
GSE60625 ZNF493 284443 9 0 2
GSE74703 ZNF493 284443 2 4 30
GSE74704 ZNF493 284443 1 3 16
TCGA ZNF493 284443 17 13 66

Total number of gains: 116; Total number of losses: 58; Total Number of normals: 314.  


 

Somatic mutations of ZNF493:

 

Generating mutation plots.

 

Highly correlated genes for ZNF493:

 

Showing top 20/735 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
ZNF493ZNF7290.755154303
ZNF493ZNF7760.713001303
ZNF493PEX11B0.706268404
ZNF493ZNF6760.700755303
ZNF493PSMD6-AS20.699388303
ZNF493ZNF6750.693521808
ZNF493ZNF6810.692372505
ZNF493ANKHD10.690114303
ZNF493PPP1R110.677474303
ZNF493EPG50.674215504
ZNF493PRR15L0.673801404
ZNF493ZNF920.670785605
ZNF493USP46-AS10.669786303
ZNF493ZNF930.66547711010
ZNF493KIAA11430.664075303
ZNF493ZNF7380.662268807
ZNF493HDHD20.660916504
ZNF493CEP440.660851303
ZNF493SARM10.660759505
ZNF493ZNF4390.659013605

For details and further investigation, click here