| Full name: ankyrin repeat and KH domain containing 1 | Alias Symbol: MASK|FLJ20288|FLJ11979|FLJ10042|FLJ14127|KIAA1085|MASK1 | ||
| Type: protein-coding gene | Cytoband: 5q31.3 | ||
| Entrez ID: 54882 | HGNC ID: HGNC:24714 | Ensembl Gene: ENSG00000131503 | OMIM ID: 610500 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
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Expression of ANKHD1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ANKHD1 | 54882 | 229457_at | -0.2469 | 0.8462 | |
| GSE26886 | ANKHD1 | 54882 | 229457_at | -0.4611 | 0.0525 | |
| GSE45670 | ANKHD1 | 54882 | 229457_at | -0.2487 | 0.1455 | |
| GSE63941 | ANKHD1 | 54882 | 229457_at | -0.8319 | 0.0006 | |
| GSE77861 | ANKHD1 | 54882 | 229457_at | -0.0904 | 0.4313 | |
| GSE97050 | ANKHD1 | 54882 | A_23_P92642 | -0.1230 | 0.5260 | |
| SRP007169 | ANKHD1 | 54882 | RNAseq | -0.1761 | 0.6445 | |
| SRP008496 | ANKHD1 | 54882 | RNAseq | 0.0466 | 0.8403 | |
| SRP064894 | ANKHD1 | 54882 | RNAseq | -0.3981 | 0.0094 | |
| SRP133303 | ANKHD1 | 54882 | RNAseq | 0.1235 | 0.6233 | |
| SRP159526 | ANKHD1 | 54882 | RNAseq | -0.1822 | 0.6509 | |
| SRP193095 | ANKHD1 | 54882 | RNAseq | -0.2787 | 0.0297 | |
| SRP219564 | ANKHD1 | 54882 | RNAseq | -0.1773 | 0.6729 | |
| TCGA | ANKHD1 | 54882 | RNAseq | -0.0282 | 0.5064 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by ANKHD1 expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of ANKHD1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ANKHD1 | 54882 | 3 | 11 | 16 | |
| GSE20123 | ANKHD1 | 54882 | 4 | 11 | 15 | |
| GSE43470 | ANKHD1 | 54882 | 2 | 10 | 31 | |
| GSE46452 | ANKHD1 | 54882 | 0 | 27 | 32 | |
| GSE47630 | ANKHD1 | 54882 | 0 | 20 | 20 | |
| GSE54993 | ANKHD1 | 54882 | 9 | 1 | 60 | |
| GSE54994 | ANKHD1 | 54882 | 2 | 14 | 37 | |
| GSE60625 | ANKHD1 | 54882 | 0 | 0 | 11 | |
| GSE74703 | ANKHD1 | 54882 | 2 | 7 | 27 | |
| GSE74704 | ANKHD1 | 54882 | 3 | 5 | 12 | |
| TCGA | ANKHD1 | 54882 | 4 | 37 | 55 |
Total number of gains: 29; Total number of losses: 143; Total Number of normals: 316.
Somatic mutations of ANKHD1:
Generating mutation plots.
Highly correlated genes for ANKHD1:
Showing top 20/348 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ANKHD1 | LIMS1 | 0.86948 | 3 | 0 | 3 |
| ANKHD1 | ZBED6 | 0.777225 | 3 | 0 | 3 |
| ANKHD1 | PGGT1B | 0.775637 | 3 | 0 | 3 |
| ANKHD1 | SNRNP200 | 0.773548 | 3 | 0 | 3 |
| ANKHD1 | NBR1 | 0.772423 | 3 | 0 | 3 |
| ANKHD1 | SLC17A5 | 0.771464 | 3 | 0 | 3 |
| ANKHD1 | IL33 | 0.765872 | 3 | 0 | 3 |
| ANKHD1 | SLTM | 0.758658 | 3 | 0 | 3 |
| ANKHD1 | ZNF426 | 0.754458 | 3 | 0 | 3 |
| ANKHD1 | SS18 | 0.750475 | 3 | 0 | 3 |
| ANKHD1 | DYNC1I2 | 0.748121 | 3 | 0 | 3 |
| ANKHD1 | SPATA5L1 | 0.74643 | 3 | 0 | 3 |
| ANKHD1 | DPY19L3 | 0.744218 | 3 | 0 | 3 |
| ANKHD1 | AVIL | 0.744186 | 3 | 0 | 3 |
| ANKHD1 | AKAP9 | 0.742289 | 3 | 0 | 3 |
| ANKHD1 | MTPN | 0.741027 | 4 | 0 | 4 |
| ANKHD1 | TBRG1 | 0.740783 | 3 | 0 | 3 |
| ANKHD1 | FBXO8 | 0.737182 | 3 | 0 | 3 |
| ANKHD1 | SCYL2 | 0.73367 | 3 | 0 | 3 |
| ANKHD1 | ATG12 | 0.732422 | 4 | 0 | 4 |
For details and further investigation, click here
