| Full name: zinc finger protein 681 | Alias Symbol: FLJ31526 | ||
| Type: protein-coding gene | Cytoband: 19p12 | ||
| Entrez ID: 148213 | HGNC ID: HGNC:26457 | Ensembl Gene: ENSG00000196172 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of ZNF681:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ZNF681 | 148213 | 238962_at | -0.4358 | 0.5235 | |
| GSE26886 | ZNF681 | 148213 | 238962_at | -0.8545 | 0.0000 | |
| GSE45670 | ZNF681 | 148213 | 238962_at | -0.1875 | 0.5930 | |
| GSE53622 | ZNF681 | 148213 | 81211 | -1.2696 | 0.0000 | |
| GSE53624 | ZNF681 | 148213 | 81211 | -1.2752 | 0.0000 | |
| GSE63941 | ZNF681 | 148213 | 236672_at | -0.0005 | 0.9982 | |
| GSE77861 | ZNF681 | 148213 | 236672_at | -0.0560 | 0.6789 | |
| GSE97050 | ZNF681 | 148213 | A_32_P167904 | -0.0246 | 0.9323 | |
| SRP007169 | ZNF681 | 148213 | RNAseq | -0.9969 | 0.1544 | |
| SRP008496 | ZNF681 | 148213 | RNAseq | -1.0816 | 0.0261 | |
| SRP064894 | ZNF681 | 148213 | RNAseq | -0.7852 | 0.0048 | |
| SRP133303 | ZNF681 | 148213 | RNAseq | 0.0175 | 0.9563 | |
| SRP159526 | ZNF681 | 148213 | RNAseq | -0.3301 | 0.4985 | |
| SRP193095 | ZNF681 | 148213 | RNAseq | -1.0705 | 0.0000 | |
| SRP219564 | ZNF681 | 148213 | RNAseq | -0.9826 | 0.1723 | |
| TCGA | ZNF681 | 148213 | RNAseq | -0.4557 | 0.1466 |
Upregulated datasets: 0; Downregulated datasets: 4.
Survival by ZNF681 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ZNF681:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ZNF681 | 148213 | 6 | 4 | 20 | |
| GSE20123 | ZNF681 | 148213 | 6 | 3 | 21 | |
| GSE43470 | ZNF681 | 148213 | 2 | 5 | 36 | |
| GSE46452 | ZNF681 | 148213 | 47 | 1 | 11 | |
| GSE47630 | ZNF681 | 148213 | 7 | 7 | 26 | |
| GSE54993 | ZNF681 | 148213 | 17 | 3 | 50 | |
| GSE54994 | ZNF681 | 148213 | 6 | 13 | 34 | |
| GSE60625 | ZNF681 | 148213 | 9 | 0 | 2 | |
| GSE74703 | ZNF681 | 148213 | 2 | 3 | 31 | |
| GSE74704 | ZNF681 | 148213 | 3 | 3 | 14 | |
| TCGA | ZNF681 | 148213 | 15 | 17 | 64 |
Total number of gains: 120; Total number of losses: 59; Total Number of normals: 309.
Somatic mutations of ZNF681:
Generating mutation plots.
Highly correlated genes for ZNF681:
Showing top 20/527 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ZNF681 | LPIN2 | 0.834568 | 3 | 0 | 3 |
| ZNF681 | OSBPL8 | 0.806829 | 4 | 0 | 4 |
| ZNF681 | HMGN1 | 0.791369 | 3 | 0 | 3 |
| ZNF681 | CRYBG3 | 0.770528 | 3 | 0 | 3 |
| ZNF681 | DCAF10 | 0.754026 | 3 | 0 | 3 |
| ZNF681 | WASF2 | 0.748805 | 3 | 0 | 3 |
| ZNF681 | TOM1 | 0.741031 | 3 | 0 | 3 |
| ZNF681 | ZNF91 | 0.734941 | 7 | 0 | 6 |
| ZNF681 | ANO8 | 0.733418 | 3 | 0 | 3 |
| ZNF681 | ZNF726 | 0.732253 | 3 | 0 | 3 |
| ZNF681 | MLKL | 0.723462 | 3 | 0 | 3 |
| ZNF681 | TRIM38 | 0.722969 | 3 | 0 | 3 |
| ZNF681 | ZNF506 | 0.718399 | 4 | 0 | 3 |
| ZNF681 | ZNF100 | 0.717329 | 5 | 0 | 5 |
| ZNF681 | PRPF38A | 0.715828 | 3 | 0 | 3 |
| ZNF681 | ZNF790 | 0.712155 | 4 | 0 | 4 |
| ZNF681 | FAM166A | 0.71195 | 3 | 0 | 3 |
| ZNF681 | TSPAN5 | 0.711236 | 3 | 0 | 3 |
| ZNF681 | SHPRH | 0.708928 | 4 | 0 | 4 |
| ZNF681 | FGFR1OP | 0.708049 | 3 | 0 | 3 |
For details and further investigation, click here
