| Full name: sterile alpha and TIR motif containing 1 | Alias Symbol: SARM|SAMD2|KIAA0524 | ||
| Type: protein-coding gene | Cytoband: 17q11.2 | ||
| Entrez ID: 23098 | HGNC ID: HGNC:17074 | Ensembl Gene: ENSG00000004139 | OMIM ID: 607732 |
| Drug and gene relationship at DGIdb | |||
Expression of SARM1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SARM1 | 23098 | 213257_at | -0.1488 | 0.7831 | |
| GSE20347 | SARM1 | 23098 | 213257_at | -0.2524 | 0.0039 | |
| GSE23400 | SARM1 | 23098 | 213257_at | -0.2624 | 0.0000 | |
| GSE26886 | SARM1 | 23098 | 213257_at | 0.0340 | 0.8599 | |
| GSE29001 | SARM1 | 23098 | 213257_at | -0.4685 | 0.0016 | |
| GSE38129 | SARM1 | 23098 | 213257_at | -0.3457 | 0.0005 | |
| GSE45670 | SARM1 | 23098 | 213257_at | -0.3888 | 0.0034 | |
| GSE53622 | SARM1 | 23098 | 46142 | -0.1794 | 0.0161 | |
| GSE53624 | SARM1 | 23098 | 46142 | -0.1844 | 0.0536 | |
| GSE63941 | SARM1 | 23098 | 213257_at | -1.2059 | 0.0034 | |
| GSE77861 | SARM1 | 23098 | 213257_at | 0.0029 | 0.9829 | |
| GSE97050 | SARM1 | 23098 | A_24_P267293 | -0.1464 | 0.4290 | |
| SRP007169 | SARM1 | 23098 | RNAseq | 0.8809 | 0.2251 | |
| SRP064894 | SARM1 | 23098 | RNAseq | -0.4151 | 0.0763 | |
| SRP133303 | SARM1 | 23098 | RNAseq | -0.4895 | 0.0001 | |
| SRP159526 | SARM1 | 23098 | RNAseq | -0.0690 | 0.8313 | |
| SRP193095 | SARM1 | 23098 | RNAseq | -0.1883 | 0.1532 | |
| SRP219564 | SARM1 | 23098 | RNAseq | -0.1124 | 0.7484 | |
| TCGA | SARM1 | 23098 | RNAseq | -0.5614 | 0.0001 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by SARM1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SARM1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SARM1 | 23098 | 9 | 1 | 20 | |
| GSE20123 | SARM1 | 23098 | 9 | 1 | 20 | |
| GSE43470 | SARM1 | 23098 | 0 | 1 | 42 | |
| GSE46452 | SARM1 | 23098 | 33 | 1 | 25 | |
| GSE47630 | SARM1 | 23098 | 7 | 1 | 32 | |
| GSE54993 | SARM1 | 23098 | 2 | 3 | 65 | |
| GSE54994 | SARM1 | 23098 | 7 | 6 | 40 | |
| GSE60625 | SARM1 | 23098 | 4 | 0 | 7 | |
| GSE74703 | SARM1 | 23098 | 0 | 1 | 35 | |
| GSE74704 | SARM1 | 23098 | 7 | 1 | 12 | |
| TCGA | SARM1 | 23098 | 21 | 10 | 65 |
Total number of gains: 99; Total number of losses: 26; Total Number of normals: 363.
Somatic mutations of SARM1:
Generating mutation plots.
Highly correlated genes for SARM1:
Showing top 20/569 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SARM1 | UBE2R2 | 0.729751 | 3 | 0 | 3 |
| SARM1 | ZIK1 | 0.729462 | 3 | 0 | 3 |
| SARM1 | GNG2 | 0.696719 | 3 | 0 | 3 |
| SARM1 | LSP1 | 0.695929 | 3 | 0 | 3 |
| SARM1 | ZNF100 | 0.694184 | 3 | 0 | 3 |
| SARM1 | C19orf18 | 0.691573 | 3 | 0 | 3 |
| SARM1 | SLAIN1 | 0.687371 | 4 | 0 | 4 |
| SARM1 | SMARCC2 | 0.675618 | 4 | 0 | 4 |
| SARM1 | SCARB2 | 0.672694 | 3 | 0 | 3 |
| SARM1 | ZNF578 | 0.671419 | 3 | 0 | 3 |
| SARM1 | TTN | 0.671183 | 3 | 0 | 3 |
| SARM1 | MYBPC3 | 0.667355 | 3 | 0 | 3 |
| SARM1 | QRICH1 | 0.661865 | 3 | 0 | 3 |
| SARM1 | CABLES1 | 0.661622 | 3 | 0 | 3 |
| SARM1 | ZNF493 | 0.660759 | 5 | 0 | 5 |
| SARM1 | CYP2C19 | 0.659354 | 3 | 0 | 3 |
| SARM1 | ANKRD65 | 0.657511 | 3 | 0 | 3 |
| SARM1 | NFIA | 0.65507 | 3 | 0 | 3 |
| SARM1 | COPS7A | 0.653561 | 3 | 0 | 3 |
| SARM1 | MLLT6 | 0.649104 | 4 | 0 | 3 |
For details and further investigation, click here
