| Full name: haloacid dehalogenase like hydrolase domain containing 2 | Alias Symbol: DKFZP564D1378 | ||
| Type: protein-coding gene | Cytoband: 18q21.1 | ||
| Entrez ID: 84064 | HGNC ID: HGNC:25364 | Ensembl Gene: ENSG00000167220 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of HDHD2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | HDHD2 | 84064 | 223155_at | -0.6448 | 0.1010 | |
| GSE26886 | HDHD2 | 84064 | 223155_at | -1.4387 | 0.0000 | |
| GSE45670 | HDHD2 | 84064 | 223155_at | -0.3677 | 0.0581 | |
| GSE63941 | HDHD2 | 84064 | 223155_at | -1.2624 | 0.0394 | |
| GSE77861 | HDHD2 | 84064 | 223155_at | -0.9125 | 0.0275 | |
| GSE97050 | HDHD2 | 84064 | A_23_P153098 | -0.5467 | 0.1313 | |
| SRP007169 | HDHD2 | 84064 | RNAseq | -0.1515 | 0.7662 | |
| SRP008496 | HDHD2 | 84064 | RNAseq | 0.4914 | 0.2539 | |
| SRP064894 | HDHD2 | 84064 | RNAseq | -0.4025 | 0.0008 | |
| SRP133303 | HDHD2 | 84064 | RNAseq | -0.4297 | 0.0222 | |
| SRP159526 | HDHD2 | 84064 | RNAseq | -0.5044 | 0.0768 | |
| SRP193095 | HDHD2 | 84064 | RNAseq | -0.6197 | 0.0000 | |
| SRP219564 | HDHD2 | 84064 | RNAseq | -0.6064 | 0.0636 | |
| TCGA | HDHD2 | 84064 | RNAseq | -0.2873 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 2.
Survival by HDHD2 expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of HDHD2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | HDHD2 | 84064 | 1 | 8 | 21 | |
| GSE20123 | HDHD2 | 84064 | 1 | 8 | 21 | |
| GSE43470 | HDHD2 | 84064 | 0 | 5 | 38 | |
| GSE46452 | HDHD2 | 84064 | 1 | 26 | 32 | |
| GSE47630 | HDHD2 | 84064 | 5 | 20 | 15 | |
| GSE54993 | HDHD2 | 84064 | 8 | 1 | 61 | |
| GSE54994 | HDHD2 | 84064 | 2 | 15 | 36 | |
| GSE60625 | HDHD2 | 84064 | 0 | 4 | 7 | |
| GSE74703 | HDHD2 | 84064 | 0 | 4 | 32 | |
| GSE74704 | HDHD2 | 84064 | 0 | 6 | 14 | |
| TCGA | HDHD2 | 84064 | 15 | 39 | 42 |
Total number of gains: 33; Total number of losses: 136; Total Number of normals: 319.
Somatic mutations of HDHD2:
Generating mutation plots.
Highly correlated genes for HDHD2:
Showing top 20/1178 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| HDHD2 | FBXO9 | 0.858795 | 4 | 0 | 4 |
| HDHD2 | RAB27B | 0.858043 | 3 | 0 | 3 |
| HDHD2 | SUCLG1 | 0.847301 | 3 | 0 | 3 |
| HDHD2 | DENND2D | 0.843792 | 3 | 0 | 3 |
| HDHD2 | GPD1L | 0.834678 | 5 | 0 | 5 |
| HDHD2 | GRHPR | 0.826441 | 3 | 0 | 3 |
| HDHD2 | CD2AP | 0.826252 | 3 | 0 | 3 |
| HDHD2 | ZNF33B | 0.824512 | 3 | 0 | 3 |
| HDHD2 | TAB3 | 0.82229 | 4 | 0 | 4 |
| HDHD2 | TAF9B | 0.820231 | 3 | 0 | 3 |
| HDHD2 | RAB11A | 0.819471 | 4 | 0 | 4 |
| HDHD2 | COBLL1 | 0.819079 | 4 | 0 | 4 |
| HDHD2 | RHBDF1 | 0.813911 | 3 | 0 | 3 |
| HDHD2 | RNF141 | 0.812907 | 4 | 0 | 4 |
| HDHD2 | MTA3 | 0.808925 | 3 | 0 | 3 |
| HDHD2 | INPP1 | 0.808074 | 4 | 0 | 4 |
| HDHD2 | ETFA | 0.80604 | 3 | 0 | 3 |
| HDHD2 | SUCLG2 | 0.805462 | 5 | 0 | 5 |
| HDHD2 | ALAS1 | 0.805276 | 3 | 0 | 3 |
| HDHD2 | ZNF654 | 0.805257 | 4 | 0 | 4 |
For details and further investigation, click here
