C2orf80

 

Full name: chromosome 2 open reading frame 80 Alias Symbol: LOC389073|GONDA1
Type: protein-coding gene Cytoband: 2q33.3
Entrez ID: 389073 HGNC ID: HGNC:34352 Ensembl Gene: ENSG00000188674 OMIM ID: 615536
Drug and gene relationship at DGIdb

 

Expression of C2orf80:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 C2orf80 389073 241998_at 0.0185 0.9367
GSE26886 C2orf80 389073 241998_at 0.0051 0.9684
GSE45670 C2orf80 389073 241998_at 0.1042 0.1344
GSE53622 C2orf80 389073 93392 -0.1113 0.5281
GSE53624 C2orf80 389073 93392 0.4587 0.0002
GSE63941 C2orf80 389073 241998_at 0.1129 0.4064
GSE77861 C2orf80 389073 241998_at -0.0913 0.2433

Upregulated datasets: 0; Downregulated datasets: 0.  

 

Survival by C2orf80 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of C2orf80:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 C2orf80 389073 3 10 17
GSE20123 C2orf80 389073 3 10 17
GSE43470 C2orf80 389073 2 4 37
GSE46452 C2orf80 389073 0 5 54
GSE47630 C2orf80 389073 4 5 31
GSE54993 C2orf80 389073 0 3 67
GSE54994 C2orf80 389073 9 9 35
GSE60625 C2orf80 389073 0 3 8
GSE74703 C2orf80 389073 2 3 31
GSE74704 C2orf80 389073 2 5 13
TCGA C2orf80 389073 15 20 61

Total number of gains: 40; Total number of losses: 77; Total Number of normals: 371.  

 

Somatic mutations of C2orf80:

 

Generating mutation plots.

 

Highly correlated genes for C2orf80:

 

Showing all 15 correlated genes with mean PCC>0.5.

Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
C2orf80SRD5A20.685513303
C2orf80ZBP10.681562303
C2orf80TSHR0.659786303
C2orf80BRWD30.619718303
C2orf80REXO10.615527404
C2orf80GLYCTK0.610962303
C2orf80ANKLE10.605673303
C2orf80CR1L0.590917303
C2orf80LMAN1L0.582392303
C2orf80FAM71E20.572994403
C2orf80HPN0.556675303
C2orf80TTLL90.555049303
C2orf80FAM71E10.53752403
C2orf80HIVEP30.525217303
C2orf80HAMP0.51957503

For details and further investigation, click here