| Full name: corin, serine peptidase | Alias Symbol: PRSC|CRN|ATC2|Lrp4|TMPRSS10 | ||
| Type: protein-coding gene | Cytoband: 4p12 | ||
| Entrez ID: 10699 | HGNC ID: HGNC:19012 | Ensembl Gene: ENSG00000145244 | OMIM ID: 605236 |
| Drug and gene relationship at DGIdb | |||
Expression of CORIN:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CORIN | 10699 | 239261_s_at | 0.0008 | 0.9987 | |
| GSE20347 | CORIN | 10699 | 220356_at | 0.1180 | 0.2501 | |
| GSE23400 | CORIN | 10699 | 220356_at | 0.0371 | 0.2591 | |
| GSE26886 | CORIN | 10699 | 239261_s_at | -0.2250 | 0.2521 | |
| GSE29001 | CORIN | 10699 | 220356_at | 0.0046 | 0.9791 | |
| GSE38129 | CORIN | 10699 | 220356_at | 0.1005 | 0.5697 | |
| GSE45670 | CORIN | 10699 | 239261_s_at | 0.0553 | 0.6451 | |
| GSE53622 | CORIN | 10699 | 22806 | 0.2392 | 0.0062 | |
| GSE53624 | CORIN | 10699 | 22806 | 0.2685 | 0.0003 | |
| GSE63941 | CORIN | 10699 | 239261_s_at | -0.8078 | 0.0022 | |
| GSE77861 | CORIN | 10699 | 239261_s_at | -0.1493 | 0.2132 | |
| GSE97050 | CORIN | 10699 | A_23_P81131 | -0.1536 | 0.5721 | |
| SRP007169 | CORIN | 10699 | RNAseq | 2.0803 | 0.0166 | |
| SRP133303 | CORIN | 10699 | RNAseq | 1.3108 | 0.0009 | |
| SRP159526 | CORIN | 10699 | RNAseq | -0.1573 | 0.7757 | |
| SRP219564 | CORIN | 10699 | RNAseq | -0.0893 | 0.8504 | |
| TCGA | CORIN | 10699 | RNAseq | 0.0362 | 0.8840 |
Upregulated datasets: 2; Downregulated datasets: 0.
Survival by CORIN expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CORIN:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CORIN | 10699 | 1 | 15 | 14 | |
| GSE20123 | CORIN | 10699 | 1 | 15 | 14 | |
| GSE43470 | CORIN | 10699 | 0 | 13 | 30 | |
| GSE46452 | CORIN | 10699 | 1 | 37 | 21 | |
| GSE47630 | CORIN | 10699 | 1 | 18 | 21 | |
| GSE54993 | CORIN | 10699 | 7 | 0 | 63 | |
| GSE54994 | CORIN | 10699 | 4 | 9 | 40 | |
| GSE60625 | CORIN | 10699 | 0 | 0 | 11 | |
| GSE74703 | CORIN | 10699 | 0 | 11 | 25 | |
| GSE74704 | CORIN | 10699 | 0 | 9 | 11 | |
| TCGA | CORIN | 10699 | 16 | 33 | 47 |
Total number of gains: 31; Total number of losses: 160; Total Number of normals: 297.
Somatic mutations of CORIN:
Generating mutation plots.
Highly correlated genes for CORIN:
Showing top 20/59 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CORIN | ARX | 0.714418 | 3 | 0 | 3 |
| CORIN | CCDC173 | 0.685988 | 3 | 0 | 3 |
| CORIN | TMEM105 | 0.672496 | 3 | 0 | 3 |
| CORIN | ST3GAL3 | 0.655891 | 3 | 0 | 3 |
| CORIN | TTTY11 | 0.649034 | 3 | 0 | 3 |
| CORIN | SPRN | 0.648602 | 4 | 0 | 3 |
| CORIN | ISM1-AS1 | 0.645189 | 3 | 0 | 3 |
| CORIN | FNDC7 | 0.635921 | 3 | 0 | 3 |
| CORIN | ZBTB46-AS1 | 0.633311 | 3 | 0 | 3 |
| CORIN | LEMD1-AS1 | 0.627914 | 3 | 0 | 3 |
| CORIN | CST8 | 0.615258 | 5 | 0 | 5 |
| CORIN | ZNF582-AS1 | 0.609224 | 3 | 0 | 3 |
| CORIN | DRICH1 | 0.608624 | 3 | 0 | 3 |
| CORIN | SLC25A53 | 0.602409 | 3 | 0 | 3 |
| CORIN | SUN5 | 0.601904 | 3 | 0 | 3 |
| CORIN | CNTN6 | 0.59625 | 3 | 0 | 3 |
| CORIN | TMEM175 | 0.595842 | 3 | 0 | 3 |
| CORIN | IQCF1 | 0.592139 | 3 | 0 | 3 |
| CORIN | LCNL1 | 0.590149 | 4 | 0 | 4 |
| CORIN | C9orf50 | 0.579826 | 3 | 0 | 3 |
For details and further investigation, click here
