| Full name: cystatin 8 | Alias Symbol: CRES|CTES5 | ||
| Type: protein-coding gene | Cytoband: 20p11.21 | ||
| Entrez ID: 10047 | HGNC ID: HGNC:2480 | Ensembl Gene: ENSG00000125815 | OMIM ID: 608683 |
| Drug and gene relationship at DGIdb | |||
Expression of CST8:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CST8 | 10047 | 220627_at | -0.0609 | 0.8769 | |
| GSE20347 | CST8 | 10047 | 220627_at | -0.0896 | 0.1186 | |
| GSE23400 | CST8 | 10047 | 220627_at | -0.2560 | 0.0000 | |
| GSE26886 | CST8 | 10047 | 220627_at | -0.0866 | 0.5289 | |
| GSE29001 | CST8 | 10047 | 220627_at | -0.0967 | 0.5530 | |
| GSE38129 | CST8 | 10047 | 220627_at | -0.1620 | 0.0167 | |
| GSE45670 | CST8 | 10047 | 220627_at | 0.0358 | 0.7362 | |
| GSE53622 | CST8 | 10047 | 68831 | 0.0160 | 0.9167 | |
| GSE53624 | CST8 | 10047 | 68831 | 0.2831 | 0.1280 | |
| GSE63941 | CST8 | 10047 | 220627_at | 0.2369 | 0.2006 | |
| GSE77861 | CST8 | 10047 | 220627_at | -0.1036 | 0.3095 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by CST8 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CST8:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CST8 | 10047 | 12 | 2 | 16 | |
| GSE20123 | CST8 | 10047 | 12 | 2 | 16 | |
| GSE43470 | CST8 | 10047 | 12 | 1 | 30 | |
| GSE46452 | CST8 | 10047 | 27 | 1 | 31 | |
| GSE47630 | CST8 | 10047 | 17 | 4 | 19 | |
| GSE54993 | CST8 | 10047 | 0 | 17 | 53 | |
| GSE54994 | CST8 | 10047 | 26 | 2 | 25 | |
| GSE60625 | CST8 | 10047 | 0 | 0 | 11 | |
| GSE74703 | CST8 | 10047 | 10 | 1 | 25 | |
| GSE74704 | CST8 | 10047 | 7 | 1 | 12 | |
| TCGA | CST8 | 10047 | 43 | 10 | 43 |
Total number of gains: 166; Total number of losses: 41; Total Number of normals: 281.
Somatic mutations of CST8:
Generating mutation plots.
Highly correlated genes for CST8:
Showing top 20/1166 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CST8 | SLC17A3 | 0.738019 | 3 | 0 | 3 |
| CST8 | OPRK1 | 0.722948 | 3 | 0 | 3 |
| CST8 | OTOR | 0.720596 | 4 | 0 | 4 |
| CST8 | GRIN1 | 0.71223 | 4 | 0 | 4 |
| CST8 | LINC00943 | 0.711871 | 3 | 0 | 3 |
| CST8 | IFNA4 | 0.710896 | 4 | 0 | 4 |
| CST8 | MRPL41 | 0.710409 | 3 | 0 | 3 |
| CST8 | TGM4 | 0.708068 | 6 | 0 | 6 |
| CST8 | NTNG1 | 0.70697 | 3 | 0 | 3 |
| CST8 | FSCN3 | 0.701065 | 4 | 0 | 4 |
| CST8 | NAT2 | 0.698539 | 4 | 0 | 3 |
| CST8 | RNF17 | 0.698193 | 3 | 0 | 3 |
| CST8 | PHOX2A | 0.69594 | 4 | 0 | 4 |
| CST8 | PRTN3 | 0.695115 | 3 | 0 | 3 |
| CST8 | HTR1A | 0.694618 | 4 | 0 | 4 |
| CST8 | SPIN2A | 0.692788 | 4 | 0 | 4 |
| CST8 | FRAS1 | 0.689246 | 3 | 0 | 3 |
| CST8 | CALCB | 0.688052 | 3 | 0 | 3 |
| CST8 | DAGLA | 0.68801 | 4 | 0 | 4 |
| CST8 | TAS2R1 | 0.686625 | 3 | 0 | 3 |
For details and further investigation, click here
