| Full name: chromosome 9 open reading frame 50 | Alias Symbol: FLJ35803 | ||
| Type: protein-coding gene | Cytoband: 9q34.11 | ||
| Entrez ID: 375759 | HGNC ID: HGNC:23677 | Ensembl Gene: ENSG00000179058 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of C9orf50:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | C9orf50 | 375759 | 230335_at | -0.0801 | 0.7935 | |
| GSE26886 | C9orf50 | 375759 | 230335_at | 0.1179 | 0.2760 | |
| GSE45670 | C9orf50 | 375759 | 230335_at | 0.0382 | 0.7414 | |
| GSE53622 | C9orf50 | 375759 | 80409 | 0.2885 | 0.0000 | |
| GSE53624 | C9orf50 | 375759 | 80409 | 0.5062 | 0.0000 | |
| GSE63941 | C9orf50 | 375759 | 230335_at | 0.0465 | 0.8190 | |
| GSE77861 | C9orf50 | 375759 | 230335_at | -0.1835 | 0.1521 | |
| GSE97050 | C9orf50 | 375759 | A_23_P406785 | -0.1672 | 0.5673 | |
| TCGA | C9orf50 | 375759 | RNAseq | -0.5376 | 0.3582 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by C9orf50 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of C9orf50:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | C9orf50 | 375759 | 6 | 9 | 15 | |
| GSE20123 | C9orf50 | 375759 | 6 | 9 | 15 | |
| GSE43470 | C9orf50 | 375759 | 5 | 8 | 30 | |
| GSE46452 | C9orf50 | 375759 | 6 | 13 | 40 | |
| GSE47630 | C9orf50 | 375759 | 3 | 16 | 21 | |
| GSE54993 | C9orf50 | 375759 | 3 | 3 | 64 | |
| GSE54994 | C9orf50 | 375759 | 12 | 9 | 32 | |
| GSE60625 | C9orf50 | 375759 | 0 | 0 | 11 | |
| GSE74703 | C9orf50 | 375759 | 5 | 6 | 25 | |
| GSE74704 | C9orf50 | 375759 | 3 | 7 | 10 | |
| TCGA | C9orf50 | 375759 | 27 | 26 | 43 |
Total number of gains: 76; Total number of losses: 106; Total Number of normals: 306.
Somatic mutations of C9orf50:
Generating mutation plots.
Highly correlated genes for C9orf50:
Showing top 20/227 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| C9orf50 | GJC2 | 0.727071 | 4 | 0 | 4 |
| C9orf50 | PLEKHA4 | 0.721595 | 3 | 0 | 3 |
| C9orf50 | GPR132 | 0.715866 | 3 | 0 | 3 |
| C9orf50 | CCR10 | 0.710626 | 4 | 0 | 4 |
| C9orf50 | ATP8B2 | 0.708274 | 4 | 0 | 4 |
| C9orf50 | TCL1B | 0.703221 | 3 | 0 | 3 |
| C9orf50 | NES | 0.699938 | 3 | 0 | 3 |
| C9orf50 | YTHDF3-AS1 | 0.698762 | 3 | 0 | 3 |
| C9orf50 | ARHGEF15 | 0.695956 | 3 | 0 | 3 |
| C9orf50 | OGG1 | 0.69337 | 3 | 0 | 3 |
| C9orf50 | ALPK3 | 0.692064 | 3 | 0 | 3 |
| C9orf50 | MAPRE3 | 0.690315 | 4 | 0 | 4 |
| C9orf50 | SYDE1 | 0.684231 | 3 | 0 | 3 |
| C9orf50 | MATN4 | 0.682307 | 4 | 0 | 4 |
| C9orf50 | EMP3 | 0.682141 | 3 | 0 | 3 |
| C9orf50 | IQCC | 0.67661 | 4 | 0 | 3 |
| C9orf50 | HKDC1 | 0.675343 | 4 | 0 | 3 |
| C9orf50 | KCNK2 | 0.673094 | 3 | 0 | 3 |
| C9orf50 | EFCAB13 | 0.671605 | 4 | 0 | 4 |
| C9orf50 | MYL2 | 0.670845 | 3 | 0 | 3 |
For details and further investigation, click here
