| Full name: ST3 beta-galactoside alpha-2,3-sialyltransferase 3 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 1p34.1 | ||
| Entrez ID: 6487 | HGNC ID: HGNC:10866 | Ensembl Gene: ENSG00000126091 | OMIM ID: 606494 |
| Drug and gene relationship at DGIdb | |||
Expression of ST3GAL3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ST3GAL3 | 6487 | 1555181_a_at | -0.4666 | 0.0571 | |
| GSE26886 | ST3GAL3 | 6487 | 1555181_a_at | -0.4501 | 0.0027 | |
| GSE45670 | ST3GAL3 | 6487 | 1555181_a_at | -0.3282 | 0.0127 | |
| GSE53622 | ST3GAL3 | 6487 | 81412 | -1.1101 | 0.0000 | |
| GSE53624 | ST3GAL3 | 6487 | 81412 | -0.8355 | 0.0000 | |
| GSE63941 | ST3GAL3 | 6487 | 1555181_a_at | 0.2165 | 0.1780 | |
| GSE77861 | ST3GAL3 | 6487 | 1555181_a_at | -0.4903 | 0.0004 | |
| GSE97050 | ST3GAL3 | 6487 | A_23_P200999 | -0.3159 | 0.2608 | |
| SRP007169 | ST3GAL3 | 6487 | RNAseq | 1.7594 | 0.0037 | |
| SRP008496 | ST3GAL3 | 6487 | RNAseq | 2.2038 | 0.0000 | |
| SRP064894 | ST3GAL3 | 6487 | RNAseq | 0.8879 | 0.0040 | |
| SRP133303 | ST3GAL3 | 6487 | RNAseq | 0.8632 | 0.0011 | |
| SRP159526 | ST3GAL3 | 6487 | RNAseq | 1.3544 | 0.0000 | |
| SRP193095 | ST3GAL3 | 6487 | RNAseq | 1.7292 | 0.0000 | |
| TCGA | ST3GAL3 | 6487 | RNAseq | -0.0434 | 0.6618 |
Upregulated datasets: 4; Downregulated datasets: 1.
Survival by ST3GAL3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ST3GAL3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ST3GAL3 | 6487 | 4 | 3 | 23 | |
| GSE20123 | ST3GAL3 | 6487 | 4 | 2 | 24 | |
| GSE43470 | ST3GAL3 | 6487 | 7 | 2 | 34 | |
| GSE46452 | ST3GAL3 | 6487 | 3 | 1 | 55 | |
| GSE47630 | ST3GAL3 | 6487 | 9 | 3 | 28 | |
| GSE54993 | ST3GAL3 | 6487 | 0 | 2 | 68 | |
| GSE54994 | ST3GAL3 | 6487 | 14 | 2 | 37 | |
| GSE60625 | ST3GAL3 | 6487 | 0 | 0 | 11 | |
| GSE74703 | ST3GAL3 | 6487 | 6 | 1 | 29 | |
| GSE74704 | ST3GAL3 | 6487 | 2 | 0 | 18 | |
| TCGA | ST3GAL3 | 6487 | 15 | 17 | 64 |
Total number of gains: 64; Total number of losses: 33; Total Number of normals: 391.
Somatic mutations of ST3GAL3:
Generating mutation plots.
Highly correlated genes for ST3GAL3:
Showing top 20/998 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ST3GAL3 | SNORA68 | 0.791127 | 4 | 0 | 4 |
| ST3GAL3 | SUMF1 | 0.786478 | 3 | 0 | 3 |
| ST3GAL3 | TMPRSS11A | 0.765445 | 3 | 0 | 3 |
| ST3GAL3 | SFTA2 | 0.758091 | 4 | 0 | 4 |
| ST3GAL3 | C19orf57 | 0.752492 | 3 | 0 | 3 |
| ST3GAL3 | NCCRP1 | 0.746252 | 3 | 0 | 3 |
| ST3GAL3 | MFSD2B | 0.74255 | 3 | 0 | 3 |
| ST3GAL3 | FAM163B | 0.73431 | 3 | 0 | 3 |
| ST3GAL3 | OTOP3 | 0.732737 | 3 | 0 | 3 |
| ST3GAL3 | PRSS27 | 0.732531 | 7 | 0 | 7 |
| ST3GAL3 | TTC9 | 0.727332 | 6 | 0 | 6 |
| ST3GAL3 | COX6A2 | 0.725127 | 3 | 0 | 3 |
| ST3GAL3 | HLA-DQB2 | 0.72445 | 4 | 0 | 4 |
| ST3GAL3 | KRTAP20-1 | 0.721782 | 3 | 0 | 3 |
| ST3GAL3 | SCNN1B | 0.721203 | 7 | 0 | 7 |
| ST3GAL3 | MMEL1 | 0.721188 | 4 | 0 | 3 |
| ST3GAL3 | HCG22 | 0.720873 | 6 | 0 | 6 |
| ST3GAL3 | LINC00092 | 0.718431 | 4 | 0 | 4 |
| ST3GAL3 | EPS8L2 | 0.717297 | 7 | 0 | 7 |
| ST3GAL3 | RNF222 | 0.717205 | 3 | 0 | 3 |
For details and further investigation, click here
