| Full name: transmembrane protein 175 | Alias Symbol: MGC4618 | ||
| Type: protein-coding gene | Cytoband: 4p16.3 | ||
| Entrez ID: 84286 | HGNC ID: HGNC:28709 | Ensembl Gene: ENSG00000127419 | OMIM ID: 616660 |
| Drug and gene relationship at DGIdb | |||
Expression of TMEM175:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TMEM175 | 84286 | 223462_at | -0.0430 | 0.9073 | |
| GSE26886 | TMEM175 | 84286 | 223462_at | -0.3458 | 0.0087 | |
| GSE45670 | TMEM175 | 84286 | 223462_at | -0.0758 | 0.4154 | |
| GSE53622 | TMEM175 | 84286 | 20344 | -0.3466 | 0.0000 | |
| GSE53624 | TMEM175 | 84286 | 20344 | -0.3999 | 0.0000 | |
| GSE63941 | TMEM175 | 84286 | 223462_at | -0.0926 | 0.7211 | |
| GSE77861 | TMEM175 | 84286 | 223462_at | -0.1259 | 0.3673 | |
| GSE97050 | TMEM175 | 84286 | A_33_P3293266 | -0.1066 | 0.5726 | |
| SRP007169 | TMEM175 | 84286 | RNAseq | -0.7058 | 0.0995 | |
| SRP008496 | TMEM175 | 84286 | RNAseq | -1.1401 | 0.0007 | |
| SRP064894 | TMEM175 | 84286 | RNAseq | 0.4357 | 0.1259 | |
| SRP133303 | TMEM175 | 84286 | RNAseq | -0.3152 | 0.1365 | |
| SRP159526 | TMEM175 | 84286 | RNAseq | -0.3458 | 0.2951 | |
| SRP193095 | TMEM175 | 84286 | RNAseq | -0.1637 | 0.3213 | |
| SRP219564 | TMEM175 | 84286 | RNAseq | 0.1708 | 0.6233 | |
| TCGA | TMEM175 | 84286 | RNAseq | -0.2359 | 0.0006 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by TMEM175 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TMEM175:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TMEM175 | 84286 | 0 | 17 | 13 | |
| GSE20123 | TMEM175 | 84286 | 0 | 15 | 15 | |
| GSE43470 | TMEM175 | 84286 | 0 | 17 | 26 | |
| GSE46452 | TMEM175 | 84286 | 1 | 36 | 22 | |
| GSE47630 | TMEM175 | 84286 | 2 | 19 | 19 | |
| GSE54993 | TMEM175 | 84286 | 11 | 0 | 59 | |
| GSE54994 | TMEM175 | 84286 | 3 | 12 | 38 | |
| GSE60625 | TMEM175 | 84286 | 0 | 0 | 11 | |
| GSE74703 | TMEM175 | 84286 | 0 | 13 | 23 | |
| GSE74704 | TMEM175 | 84286 | 0 | 8 | 12 | |
| TCGA | TMEM175 | 84286 | 9 | 47 | 40 |
Total number of gains: 26; Total number of losses: 184; Total Number of normals: 278.
Somatic mutations of TMEM175:
Generating mutation plots.
Highly correlated genes for TMEM175:
Showing top 20/47 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TMEM175 | TBKBP1 | 0.700351 | 3 | 0 | 3 |
| TMEM175 | MVK | 0.685838 | 3 | 0 | 3 |
| TMEM175 | SEMA6C | 0.683107 | 3 | 0 | 3 |
| TMEM175 | KRTAP5-AS1 | 0.64864 | 3 | 0 | 3 |
| TMEM175 | CCDC153 | 0.623282 | 4 | 0 | 3 |
| TMEM175 | ARSF | 0.619818 | 3 | 0 | 3 |
| TMEM175 | CALCOCO1 | 0.611701 | 4 | 0 | 4 |
| TMEM175 | TEF | 0.6089 | 3 | 0 | 3 |
| TMEM175 | MAGI3 | 0.606379 | 3 | 0 | 3 |
| TMEM175 | ACADS | 0.600388 | 3 | 0 | 3 |
| TMEM175 | TOLLIP | 0.596418 | 3 | 0 | 3 |
| TMEM175 | CORIN | 0.595842 | 3 | 0 | 3 |
| TMEM175 | MOB2 | 0.595373 | 4 | 0 | 3 |
| TMEM175 | NRAP | 0.58489 | 3 | 0 | 3 |
| TMEM175 | FAM107A | 0.582385 | 4 | 0 | 3 |
| TMEM175 | CACFD1 | 0.581629 | 5 | 0 | 3 |
| TMEM175 | OPRD1 | 0.580921 | 4 | 0 | 3 |
| TMEM175 | CD40LG | 0.58092 | 4 | 0 | 3 |
| TMEM175 | NDUFC1 | 0.571324 | 4 | 0 | 3 |
| TMEM175 | CST3 | 0.564397 | 4 | 0 | 3 |
For details and further investigation, click here
