COX7B2

 

Full name: cytochrome c oxidase subunit 7B2 Alias Symbol: 
Type: protein-coding gene Cytoband: 4p12
Entrez ID: 170712 HGNC ID: HGNC:24381 Ensembl Gene: ENSG00000170516 OMIM ID: 609811
Drug and gene relationship at DGIdb

 

Expression of COX7B2:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 COX7B2 170712 231265_at 0.9956 0.6433
GSE26886 COX7B2 170712 231265_at 0.3500 0.1531
GSE45670 COX7B2 170712 231265_at 0.2878 0.1684
GSE53622 COX7B2 170712 25582 0.6063 0.0100
GSE53624 COX7B2 170712 25582 0.8846 0.0030
GSE63941 COX7B2 170712 231265_at 0.2201 0.1539
GSE77861 COX7B2 170712 231265_at -0.0335 0.7287
TCGA COX7B2 170712 RNAseq 4.5693 0.0346

Upregulated datasets: 1; Downregulated datasets: 0.  

 

Survival by COX7B2 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of COX7B2:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 COX7B2 170712 1 15 14
GSE20123 COX7B2 170712 1 15 14
GSE43470 COX7B2 170712 0 14 29
GSE46452 COX7B2 170712 1 37 21
GSE47630 COX7B2 170712 1 18 21
GSE54993 COX7B2 170712 7 0 63
GSE54994 COX7B2 170712 4 9 40
GSE60625 COX7B2 170712 0 0 11
GSE74703 COX7B2 170712 0 12 24
GSE74704 COX7B2 170712 0 9 11
TCGA COX7B2 170712 15 34 47

Total number of gains: 30; Total number of losses: 163; Total Number of normals: 295.  

 

Somatic mutations of COX7B2:

 

Generating mutation plots.

 

Highly correlated genes for COX7B2:

 

Showing all 12 correlated genes with mean PCC>0.5.

Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
COX7B2CHST90.674793303
COX7B2INPP5B0.658993303
COX7B2THAP70.623159303
COX7B2TIMM130.619636303
COX7B2LINC013050.619146503
COX7B2TBCCD10.59023303
COX7B2PXN-AS10.586654403
COX7B2TRIM280.575216303
COX7B2TBX200.573083303
COX7B2EPHA1-AS10.551333403
COX7B2IGFBP10.537692303
COX7B2WDHD10.514997403

For details and further investigation, click here