| Full name: T-box transcription factor 20 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 7p14.2 | ||
| Entrez ID: 57057 | HGNC ID: HGNC:11598 | Ensembl Gene: ENSG00000164532 | OMIM ID: 606061 |
| Drug and gene relationship at DGIdb | |||
Expression of TBX20:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TBX20 | 57057 | 1564945_at | 0.0590 | 0.7586 | |
| GSE26886 | TBX20 | 57057 | 1564945_at | 0.2868 | 0.0046 | |
| GSE45670 | TBX20 | 57057 | 1564945_at | -0.0690 | 0.3601 | |
| GSE53622 | TBX20 | 57057 | 61589 | 1.8737 | 0.0000 | |
| GSE53624 | TBX20 | 57057 | 61589 | 2.2959 | 0.0000 | |
| GSE63941 | TBX20 | 57057 | 1564945_at | 0.2410 | 0.1431 | |
| GSE77861 | TBX20 | 57057 | 1564945_at | -0.0728 | 0.4740 | |
| GSE97050 | TBX20 | 57057 | A_24_P211849 | 0.0827 | 0.6757 | |
| TCGA | TBX20 | 57057 | RNAseq | 1.6802 | 0.1289 |
Upregulated datasets: 2; Downregulated datasets: 0.
Survival by TBX20 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TBX20:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TBX20 | 57057 | 16 | 0 | 14 | |
| GSE20123 | TBX20 | 57057 | 16 | 0 | 14 | |
| GSE43470 | TBX20 | 57057 | 4 | 0 | 39 | |
| GSE46452 | TBX20 | 57057 | 11 | 1 | 47 | |
| GSE47630 | TBX20 | 57057 | 8 | 1 | 31 | |
| GSE54993 | TBX20 | 57057 | 0 | 7 | 63 | |
| GSE54994 | TBX20 | 57057 | 20 | 2 | 31 | |
| GSE60625 | TBX20 | 57057 | 0 | 0 | 11 | |
| GSE74703 | TBX20 | 57057 | 4 | 0 | 32 | |
| GSE74704 | TBX20 | 57057 | 10 | 0 | 10 | |
| TCGA | TBX20 | 57057 | 55 | 6 | 35 |
Total number of gains: 144; Total number of losses: 17; Total Number of normals: 327.
Somatic mutations of TBX20:
Generating mutation plots.
Highly correlated genes for TBX20:
Showing top 20/156 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TBX20 | SNRNP25 | 0.717001 | 3 | 0 | 3 |
| TBX20 | SFT2D3 | 0.715643 | 3 | 0 | 3 |
| TBX20 | TRAPPC5 | 0.705414 | 3 | 0 | 3 |
| TBX20 | TRAF7 | 0.696985 | 3 | 0 | 3 |
| TBX20 | ARAP1 | 0.694826 | 3 | 0 | 3 |
| TBX20 | TMEM41A | 0.690504 | 3 | 0 | 3 |
| TBX20 | LRTOMT | 0.686372 | 4 | 0 | 4 |
| TBX20 | ZNF771 | 0.683452 | 3 | 0 | 3 |
| TBX20 | STEAP1 | 0.678775 | 3 | 0 | 3 |
| TBX20 | USP5 | 0.669465 | 4 | 0 | 3 |
| TBX20 | SIX6 | 0.66896 | 3 | 0 | 3 |
| TBX20 | NIPA1 | 0.668244 | 3 | 0 | 3 |
| TBX20 | ASB7 | 0.66665 | 3 | 0 | 3 |
| TBX20 | C9orf116 | 0.664644 | 3 | 0 | 3 |
| TBX20 | NF2 | 0.662892 | 4 | 0 | 4 |
| TBX20 | MED19 | 0.66217 | 3 | 0 | 3 |
| TBX20 | GPN1 | 0.647995 | 4 | 0 | 3 |
| TBX20 | HOXA7 | 0.646333 | 4 | 0 | 3 |
| TBX20 | SORBS3 | 0.645265 | 3 | 0 | 3 |
| TBX20 | SLC39A3 | 0.644875 | 3 | 0 | 3 |
For details and further investigation, click here
