TBCCD1

 

Full name: TBCC domain containing 1 Alias Symbol: FLJ10560
Type: protein-coding gene Cytoband: 3q27.3
Entrez ID: 55171 HGNC ID: HGNC:25546 Ensembl Gene: ENSG00000113838 OMIM ID: 
Drug and gene relationship at DGIdb

 

Expression of TBCCD1:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 TBCCD1 55171 206451_at 0.5604 0.2492
GSE20347 TBCCD1 55171 206451_at 0.8092 0.0000
GSE23400 TBCCD1 55171 206451_at 0.5215 0.0000
GSE26886 TBCCD1 55171 206451_at 0.9394 0.0000
GSE29001 TBCCD1 55171 206451_at 0.6416 0.0097
GSE38129 TBCCD1 55171 206451_at 0.9296 0.0000
GSE45670 TBCCD1 55171 206451_at 0.7971 0.0001
GSE53622 TBCCD1 55171 35417 0.5791 0.0000
GSE53624 TBCCD1 55171 35417 0.4560 0.0000
GSE63941 TBCCD1 55171 206451_at 1.0920 0.0806
GSE77861 TBCCD1 55171 206451_at 0.3839 0.0212
GSE97050 TBCCD1 55171 A_23_P121345 0.4368 0.1421
SRP007169 TBCCD1 55171 RNAseq 1.0102 0.0098
SRP008496 TBCCD1 55171 RNAseq 1.1137 0.0000
SRP064894 TBCCD1 55171 RNAseq 0.7434 0.0000
SRP133303 TBCCD1 55171 RNAseq 0.8846 0.0000
SRP159526 TBCCD1 55171 RNAseq 1.0089 0.0001
SRP193095 TBCCD1 55171 RNAseq 0.3884 0.0000
SRP219564 TBCCD1 55171 RNAseq 0.4420 0.2722
TCGA TBCCD1 55171 RNAseq 0.2228 0.0003

Upregulated datasets: 3; Downregulated datasets: 0.  

 

Survival by TBCCD1 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of TBCCD1:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 TBCCD1 55171 24 0 6
GSE20123 TBCCD1 55171 24 0 6
GSE43470 TBCCD1 55171 23 0 20
GSE46452 TBCCD1 55171 19 1 39
GSE47630 TBCCD1 55171 27 2 11
GSE54993 TBCCD1 55171 1 19 50
GSE54994 TBCCD1 55171 40 0 13
GSE60625 TBCCD1 55171 0 6 5
GSE74703 TBCCD1 55171 20 0 16
GSE74704 TBCCD1 55171 16 0 4
TCGA TBCCD1 55171 77 0 19

Total number of gains: 271; Total number of losses: 28; Total Number of normals: 189.  

 

Somatic mutations of TBCCD1:

 

Generating mutation plots.

 

Highly correlated genes for TBCCD1:

 

Showing top 20/801 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
TBCCD1ACTL6A0.77905411011
TBCCD1POLR2H0.75293910010
TBCCD1ALG30.746707808
TBCCD1OAZ10.720393606
TBCCD1RFC40.71680112011
TBCCD1ATR0.71306310010
TBCCD1PSMD20.7084651009
TBCCD1ABCF30.706195807
TBCCD1RASGEF1A0.701832303
TBCCD1TBL1XR10.701414909
TBCCD1G2E30.69085404
TBCCD1ECT20.68567612010
TBCCD1OIP50.68536808
TBCCD1DNAJB110.684949605
TBCCD1RPL39L0.68459810010
TBCCD1ATP2C10.678838908
TBCCD1RUVBL10.67738811011
TBCCD1B3GNT50.675314404
TBCCD1CDR2L0.669352404
TBCCD1NOB10.669326303

For details and further investigation, click here