| Full name: THAP domain containing 7 | Alias Symbol: MGC10963 | ||
| Type: protein-coding gene | Cytoband: 22q11.21 | ||
| Entrez ID: 80764 | HGNC ID: HGNC:23190 | Ensembl Gene: ENSG00000184436 | OMIM ID: 609518 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
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Expression of THAP7:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | THAP7 | 80764 | 218492_s_at | 0.4432 | 0.3687 | |
| GSE20347 | THAP7 | 80764 | 218492_s_at | 0.1436 | 0.1864 | |
| GSE23400 | THAP7 | 80764 | 218492_s_at | 0.0577 | 0.3055 | |
| GSE26886 | THAP7 | 80764 | 218492_s_at | 0.3574 | 0.0423 | |
| GSE29001 | THAP7 | 80764 | 218492_s_at | 0.0793 | 0.5867 | |
| GSE38129 | THAP7 | 80764 | 218492_s_at | 0.2863 | 0.0689 | |
| GSE45670 | THAP7 | 80764 | 218492_s_at | 0.4230 | 0.1658 | |
| GSE53622 | THAP7 | 80764 | 35044 | 0.3306 | 0.0000 | |
| GSE53624 | THAP7 | 80764 | 35044 | 0.3404 | 0.0000 | |
| GSE63941 | THAP7 | 80764 | 218492_s_at | 0.4479 | 0.3434 | |
| GSE77861 | THAP7 | 80764 | 218492_s_at | 0.1963 | 0.3459 | |
| GSE97050 | THAP7 | 80764 | A_23_P109410 | 0.0792 | 0.8053 | |
| SRP007169 | THAP7 | 80764 | RNAseq | 0.4624 | 0.2962 | |
| SRP008496 | THAP7 | 80764 | RNAseq | 0.6798 | 0.0422 | |
| SRP064894 | THAP7 | 80764 | RNAseq | 0.9754 | 0.0056 | |
| SRP133303 | THAP7 | 80764 | RNAseq | 0.0727 | 0.7099 | |
| SRP159526 | THAP7 | 80764 | RNAseq | 0.5804 | 0.0342 | |
| SRP193095 | THAP7 | 80764 | RNAseq | 0.3543 | 0.0133 | |
| SRP219564 | THAP7 | 80764 | RNAseq | 0.5445 | 0.1693 | |
| TCGA | THAP7 | 80764 | RNAseq | 0.0147 | 0.8215 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by THAP7 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of THAP7:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | THAP7 | 80764 | 6 | 7 | 17 | |
| GSE20123 | THAP7 | 80764 | 6 | 7 | 17 | |
| GSE43470 | THAP7 | 80764 | 3 | 7 | 33 | |
| GSE46452 | THAP7 | 80764 | 33 | 1 | 25 | |
| GSE47630 | THAP7 | 80764 | 8 | 5 | 27 | |
| GSE54993 | THAP7 | 80764 | 3 | 6 | 61 | |
| GSE54994 | THAP7 | 80764 | 11 | 7 | 35 | |
| GSE60625 | THAP7 | 80764 | 5 | 0 | 6 | |
| GSE74703 | THAP7 | 80764 | 3 | 5 | 28 | |
| GSE74704 | THAP7 | 80764 | 3 | 4 | 13 | |
| TCGA | THAP7 | 80764 | 27 | 17 | 52 |
Total number of gains: 108; Total number of losses: 66; Total Number of normals: 314.
Somatic mutations of THAP7:
Generating mutation plots.
Highly correlated genes for THAP7:
Showing top 20/693 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| THAP7 | SOX13 | 0.767174 | 3 | 0 | 3 |
| THAP7 | MID1IP1 | 0.76708 | 3 | 0 | 3 |
| THAP7 | SNAPIN | 0.747671 | 3 | 0 | 3 |
| THAP7 | ZNF322 | 0.746338 | 3 | 0 | 3 |
| THAP7 | ADCK1 | 0.728835 | 3 | 0 | 3 |
| THAP7 | SMARCC1 | 0.728281 | 3 | 0 | 3 |
| THAP7 | UBP1 | 0.719149 | 3 | 0 | 3 |
| THAP7 | NACC1 | 0.713577 | 4 | 0 | 4 |
| THAP7 | URM1 | 0.712673 | 3 | 0 | 3 |
| THAP7 | TBC1D25 | 0.712457 | 3 | 0 | 3 |
| THAP7 | COMMD7 | 0.708148 | 4 | 0 | 4 |
| THAP7 | ZNF518B | 0.703327 | 3 | 0 | 3 |
| THAP7 | MRPL11 | 0.702756 | 3 | 0 | 3 |
| THAP7 | SPHK2 | 0.702421 | 3 | 0 | 3 |
| THAP7 | ZGPAT | 0.702103 | 3 | 0 | 3 |
| THAP7 | CERS5 | 0.701282 | 3 | 0 | 3 |
| THAP7 | ZNF740 | 0.700009 | 4 | 0 | 4 |
| THAP7 | ZNF628 | 0.690866 | 4 | 0 | 4 |
| THAP7 | SPSB2 | 0.690732 | 6 | 0 | 6 |
| THAP7 | NTPCR | 0.689233 | 3 | 0 | 3 |
For details and further investigation, click here
