EML5

 

Full name: EMAP like 5 Alias Symbol: HuEMAP-2|EMAP-2
Type: protein-coding gene Cytoband: 14q31.3
Entrez ID: 161436 HGNC ID: HGNC:18197 Ensembl Gene: ENSG00000165521 OMIM ID: 618119
Drug and gene relationship at DGIdb

 

Expression of EML5:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 EML5 161436 1568777_at 0.6317 0.4067
GSE26886 EML5 161436 1568777_at 0.3425 0.1235
GSE45670 EML5 161436 1568777_at 0.4715 0.2312
GSE63941 EML5 161436 1568777_at -0.0390 0.9428
GSE77861 EML5 161436 1570393_at 0.0446 0.6619
GSE97050 EML5 161436 A_33_P3230558 0.0783 0.7528
SRP007169 EML5 161436 RNAseq 0.5350 0.4858
SRP008496 EML5 161436 RNAseq 1.6450 0.0335
SRP064894 EML5 161436 RNAseq 0.3224 0.5477
SRP133303 EML5 161436 RNAseq 0.5175 0.3502
SRP159526 EML5 161436 RNAseq 0.1051 0.8477
SRP193095 EML5 161436 RNAseq 0.0222 0.9343
SRP219564 EML5 161436 RNAseq -0.2976 0.6322
TCGA EML5 161436 RNAseq -0.1384 0.4976

Upregulated datasets: 1; Downregulated datasets: 0.  


 

Survival by EML5 expression:

 

TCGA

 

Note: Click image to view full size file.  


Copy number change of EML5:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 EML5 161436 7 4 19
GSE20123 EML5 161436 7 4 19
GSE43470 EML5 161436 7 3 33
GSE46452 EML5 161436 16 3 40
GSE47630 EML5 161436 11 8 21
GSE54993 EML5 161436 3 8 59
GSE54994 EML5 161436 19 4 30
GSE60625 EML5 161436 0 2 9
GSE74703 EML5 161436 6 3 27
GSE74704 EML5 161436 4 4 12
TCGA EML5 161436 30 21 45

Total number of gains: 110; Total number of losses: 64; Total Number of normals: 314.  


 

Somatic mutations of EML5:

 

Generating mutation plots.

 

Highly correlated genes for EML5:

 

Showing all 14 correlated genes with mean PCC>0.5.

Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
EML5L3HYPDH0.74242303
EML5GNG40.683313303
EML5DCAF170.664088303
EML5IKBKG0.625938303
EML5STON20.611319403
EML5SLC7A80.601714303
EML5WDR910.601299403
EML5TTPAL0.562592303
EML5EN10.560835503
EML5NR2E10.560668503
EML5IFNLR10.541581303
EML5LTB4R0.534473403
EML5CEACAM190.531418403
EML5SATB20.50532503

For details and further investigation, click here