| Full name: leukotriene B4 receptor | Alias Symbol: BLTR|P2Y7|LTB4R1 | ||
| Type: protein-coding gene | Cytoband: 14q12 | ||
| Entrez ID: 1241 | HGNC ID: HGNC:6713 | Ensembl Gene: ENSG00000213903 | OMIM ID: 601531 |
| Drug and gene relationship at DGIdb | |||
Expression of LTB4R:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | LTB4R | 1241 | 216388_s_at | 0.1166 | 0.9592 | |
| GSE20347 | LTB4R | 1241 | 210128_s_at | -0.1746 | 0.5759 | |
| GSE23400 | LTB4R | 1241 | 216388_s_at | -0.0124 | 0.9078 | |
| GSE26886 | LTB4R | 1241 | 236172_at | -0.6790 | 0.1543 | |
| GSE29001 | LTB4R | 1241 | 210128_s_at | -0.1645 | 0.7627 | |
| GSE38129 | LTB4R | 1241 | 210128_s_at | 0.1867 | 0.5549 | |
| GSE45670 | LTB4R | 1241 | 236172_at | 0.3901 | 0.1789 | |
| GSE53622 | LTB4R | 1241 | 97945 | -0.1835 | 0.1897 | |
| GSE53624 | LTB4R | 1241 | 97945 | -0.1867 | 0.0443 | |
| GSE63941 | LTB4R | 1241 | 216388_s_at | 0.6893 | 0.1683 | |
| GSE77861 | LTB4R | 1241 | 210128_s_at | 0.5132 | 0.0917 | |
| GSE97050 | LTB4R | 1241 | A_23_P151791 | 0.1635 | 0.5033 | |
| SRP007169 | LTB4R | 1241 | RNAseq | -1.1440 | 0.0080 | |
| SRP008496 | LTB4R | 1241 | RNAseq | -0.8890 | 0.0099 | |
| SRP064894 | LTB4R | 1241 | RNAseq | 0.0731 | 0.8274 | |
| SRP133303 | LTB4R | 1241 | RNAseq | -0.2339 | 0.4479 | |
| SRP159526 | LTB4R | 1241 | RNAseq | -0.6938 | 0.0699 | |
| SRP193095 | LTB4R | 1241 | RNAseq | -0.0605 | 0.8563 | |
| SRP219564 | LTB4R | 1241 | RNAseq | -1.1051 | 0.1623 | |
| TCGA | LTB4R | 1241 | RNAseq | 0.8033 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by LTB4R expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of LTB4R:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | LTB4R | 1241 | 8 | 3 | 19 | |
| GSE20123 | LTB4R | 1241 | 8 | 3 | 19 | |
| GSE43470 | LTB4R | 1241 | 8 | 2 | 33 | |
| GSE46452 | LTB4R | 1241 | 16 | 2 | 41 | |
| GSE47630 | LTB4R | 1241 | 11 | 10 | 19 | |
| GSE54993 | LTB4R | 1241 | 3 | 11 | 56 | |
| GSE54994 | LTB4R | 1241 | 18 | 5 | 30 | |
| GSE60625 | LTB4R | 1241 | 0 | 2 | 9 | |
| GSE74703 | LTB4R | 1241 | 7 | 2 | 27 | |
| GSE74704 | LTB4R | 1241 | 3 | 2 | 15 | |
| TCGA | LTB4R | 1241 | 27 | 12 | 57 |
Total number of gains: 109; Total number of losses: 54; Total Number of normals: 325.
Somatic mutations of LTB4R:
Generating mutation plots.
Highly correlated genes for LTB4R:
Showing top 20/208 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| LTB4R | GPR39 | 0.731813 | 3 | 0 | 3 |
| LTB4R | TCHH | 0.727654 | 3 | 0 | 3 |
| LTB4R | PDCL | 0.717815 | 3 | 0 | 3 |
| LTB4R | PSMB5 | 0.696059 | 4 | 0 | 3 |
| LTB4R | PICK1 | 0.69298 | 3 | 0 | 3 |
| LTB4R | TTC5 | 0.692832 | 3 | 0 | 3 |
| LTB4R | CCDC142 | 0.683943 | 3 | 0 | 3 |
| LTB4R | GTF2IRD2 | 0.680358 | 3 | 0 | 3 |
| LTB4R | TUT1 | 0.678357 | 4 | 0 | 3 |
| LTB4R | ZNF821 | 0.670003 | 5 | 0 | 4 |
| LTB4R | PGLYRP1 | 0.667884 | 3 | 0 | 3 |
| LTB4R | KIFC2 | 0.654071 | 4 | 0 | 4 |
| LTB4R | TFAP2E | 0.651345 | 4 | 0 | 3 |
| LTB4R | TSPAN10 | 0.651125 | 4 | 0 | 3 |
| LTB4R | MATK | 0.649686 | 4 | 0 | 4 |
| LTB4R | C19orf81 | 0.642076 | 3 | 0 | 3 |
| LTB4R | DCD | 0.641593 | 4 | 0 | 3 |
| LTB4R | RUNDC3A | 0.641267 | 4 | 0 | 3 |
| LTB4R | BCL11B | 0.636082 | 8 | 0 | 7 |
| LTB4R | FOLR3 | 0.634646 | 4 | 0 | 3 |
For details and further investigation, click here
