HMX3

 

Full name: H6 family homeobox 3 Alias Symbol: NKX5-1
Type: protein-coding gene Cytoband: 10q26.13
Entrez ID: 340784 HGNC ID: HGNC:5019 Ensembl Gene: ENSG00000188620 OMIM ID: 613380
Drug and gene relationship at DGIdb

 

Expression of HMX3:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE53622 HMX3 340784 3875 0.1430 0.0500
GSE53624 HMX3 340784 3875 0.0227 0.7669
GSE97050 HMX3 340784 A_33_P3252146 0.1197 0.6097
TCGA HMX3 340784 RNAseq -1.0078 0.5013

Upregulated datasets: 0; Downregulated datasets: 0.  

 

Survival by HMX3 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of HMX3:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 HMX3 340784 1 6 23
GSE20123 HMX3 340784 1 6 23
GSE43470 HMX3 340784 0 9 34
GSE46452 HMX3 340784 0 11 48
GSE47630 HMX3 340784 2 14 24
GSE54993 HMX3 340784 8 1 61
GSE54994 HMX3 340784 1 9 43
GSE60625 HMX3 340784 0 0 11
GSE74703 HMX3 340784 0 6 30
GSE74704 HMX3 340784 1 2 17
TCGA HMX3 340784 4 27 65

Total number of gains: 18; Total number of losses: 91; Total Number of normals: 379.  

 

Somatic mutations of HMX3:

 

Generating mutation plots.

 

Highly correlated genes for HMX3:

 

Showing all 10 correlated genes with mean PCC>0.5.

Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
HMX3C2CD4D0.749977303
HMX3SNED10.736389303
HMX3CA60.723315303
HMX3PKLR0.721893303
HMX3QRFP0.707154303
HMX3KRT350.707055303
HMX3OR5A10.705901303
HMX3PRR70.675439303
HMX3HES30.624893303
HMX3PANX20.618184303

For details and further investigation, click here