| Full name: proline rich 7, synaptic | Alias Symbol: MGC10772 | ||
| Type: protein-coding gene | Cytoband: 5q35.3 | ||
| Entrez ID: 80758 | HGNC ID: HGNC:28130 | Ensembl Gene: ENSG00000131188 | OMIM ID: 618306 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of PRR7:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PRR7 | 80758 | 219742_at | 0.7123 | 0.1039 | |
| GSE20347 | PRR7 | 80758 | 219742_at | 0.3191 | 0.0035 | |
| GSE23400 | PRR7 | 80758 | 219742_at | 0.3055 | 0.0000 | |
| GSE26886 | PRR7 | 80758 | 219742_at | 0.5393 | 0.0001 | |
| GSE29001 | PRR7 | 80758 | 219742_at | 0.0718 | 0.6337 | |
| GSE38129 | PRR7 | 80758 | 219742_at | 0.5738 | 0.0000 | |
| GSE45670 | PRR7 | 80758 | 219742_at | 0.3891 | 0.0446 | |
| GSE53622 | PRR7 | 80758 | 41567 | 0.0659 | 0.2376 | |
| GSE53624 | PRR7 | 80758 | 41567 | 0.0789 | 0.1403 | |
| GSE63941 | PRR7 | 80758 | 219742_at | 0.8573 | 0.1307 | |
| GSE77861 | PRR7 | 80758 | 219742_at | 0.3848 | 0.0401 | |
| GSE97050 | PRR7 | 80758 | A_23_P30464 | 0.1602 | 0.4636 | |
| SRP007169 | PRR7 | 80758 | RNAseq | 0.4115 | 0.5403 | |
| SRP133303 | PRR7 | 80758 | RNAseq | 0.6675 | 0.0593 | |
| SRP159526 | PRR7 | 80758 | RNAseq | 1.3075 | 0.0002 | |
| SRP219564 | PRR7 | 80758 | RNAseq | 1.0384 | 0.0700 | |
| TCGA | PRR7 | 80758 | RNAseq | 0.9567 | 0.0000 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by PRR7 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PRR7:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PRR7 | 80758 | 2 | 13 | 15 | |
| GSE20123 | PRR7 | 80758 | 2 | 13 | 15 | |
| GSE43470 | PRR7 | 80758 | 1 | 11 | 31 | |
| GSE46452 | PRR7 | 80758 | 0 | 27 | 32 | |
| GSE47630 | PRR7 | 80758 | 1 | 20 | 19 | |
| GSE54993 | PRR7 | 80758 | 10 | 2 | 58 | |
| GSE54994 | PRR7 | 80758 | 2 | 17 | 34 | |
| GSE60625 | PRR7 | 80758 | 1 | 0 | 10 | |
| GSE74703 | PRR7 | 80758 | 1 | 7 | 28 | |
| GSE74704 | PRR7 | 80758 | 1 | 6 | 13 | |
| TCGA | PRR7 | 80758 | 8 | 34 | 54 |
Total number of gains: 29; Total number of losses: 150; Total Number of normals: 309.
Somatic mutations of PRR7:
Generating mutation plots.
Highly correlated genes for PRR7:
Showing top 20/661 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PRR7 | IGSF8 | 0.768103 | 3 | 0 | 3 |
| PRR7 | ARVCF | 0.756051 | 3 | 0 | 3 |
| PRR7 | EVX1 | 0.745152 | 4 | 0 | 4 |
| PRR7 | C2CD4D | 0.741461 | 3 | 0 | 3 |
| PRR7 | KCNH3 | 0.733061 | 3 | 0 | 3 |
| PRR7 | STRC | 0.732013 | 3 | 0 | 3 |
| PRR7 | THAP3 | 0.722992 | 3 | 0 | 3 |
| PRR7 | MUCL1 | 0.711547 | 3 | 0 | 3 |
| PRR7 | VAV2 | 0.707889 | 5 | 0 | 4 |
| PRR7 | SBNO2 | 0.707794 | 4 | 0 | 3 |
| PRR7 | LIM2 | 0.703495 | 3 | 0 | 3 |
| PRR7 | ZDHHC8 | 0.701342 | 4 | 0 | 3 |
| PRR7 | MRGBP | 0.69874 | 8 | 0 | 8 |
| PRR7 | CD72 | 0.698496 | 3 | 0 | 3 |
| PRR7 | FGFR4 | 0.692115 | 3 | 0 | 3 |
| PRR7 | C19orf71 | 0.689498 | 3 | 0 | 3 |
| PRR7 | SLC22A31 | 0.688485 | 3 | 0 | 3 |
| PRR7 | WDR66 | 0.68766 | 4 | 0 | 3 |
| PRR7 | AIFM3 | 0.686693 | 4 | 0 | 3 |
| PRR7 | ELOVL3 | 0.682712 | 4 | 0 | 4 |
For details and further investigation, click here
