| Full name: hes family bHLH transcription factor 3 | Alias Symbol: bHLHb43 | ||
| Type: protein-coding gene | Cytoband: 1p36.31 | ||
| Entrez ID: 390992 | HGNC ID: HGNC:26226 | Ensembl Gene: ENSG00000173673 | OMIM ID: 609971 |
Expression of HES3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE53622 | HES3 | 390992 | 71064 | 0.2793 | 0.0011 | |
| GSE53624 | HES3 | 390992 | 71064 | 0.0092 | 0.9448 | |
| GSE97050 | HES3 | 390992 | A_33_P3379896 | -0.0805 | 0.6770 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by HES3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of HES3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | HES3 | 390992 | 3 | 6 | 21 | |
| GSE20123 | HES3 | 390992 | 3 | 5 | 22 | |
| GSE43470 | HES3 | 390992 | 6 | 5 | 32 | |
| GSE46452 | HES3 | 390992 | 7 | 1 | 51 | |
| GSE47630 | HES3 | 390992 | 8 | 4 | 28 | |
| GSE54993 | HES3 | 390992 | 3 | 2 | 65 | |
| GSE54994 | HES3 | 390992 | 14 | 3 | 36 | |
| GSE60625 | HES3 | 390992 | 0 | 0 | 11 | |
| GSE74703 | HES3 | 390992 | 5 | 3 | 28 | |
| GSE74704 | HES3 | 390992 | 3 | 0 | 17 | |
| TCGA | HES3 | 390992 | 12 | 22 | 62 |
Total number of gains: 64; Total number of losses: 51; Total Number of normals: 373.
Somatic mutations of HES3:
Generating mutation plots.
Highly correlated genes for HES3:
Showing all 16 correlated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| HES3 | CDC6 | 0.660777 | 3 | 0 | 3 |
| HES3 | KRT35 | 0.654403 | 3 | 0 | 3 |
| HES3 | PKLR | 0.637399 | 3 | 0 | 3 |
| HES3 | SLC6A18 | 0.633325 | 3 | 0 | 3 |
| HES3 | HMX3 | 0.624893 | 3 | 0 | 3 |
| HES3 | C2CD4D | 0.623999 | 3 | 0 | 3 |
| HES3 | SNED1 | 0.622834 | 3 | 0 | 3 |
| HES3 | TRIM46 | 0.621146 | 3 | 0 | 3 |
| HES3 | NTNG2 | 0.61371 | 3 | 0 | 3 |
| HES3 | KLRG2 | 0.602281 | 3 | 0 | 3 |
| HES3 | PRDM13 | 0.586399 | 3 | 0 | 3 |
| HES3 | FAM131A | 0.580909 | 3 | 0 | 3 |
| HES3 | TAS2R30 | 0.578557 | 3 | 0 | 3 |
| HES3 | LTK | 0.56159 | 3 | 0 | 3 |
| HES3 | ZNF692 | 0.532585 | 3 | 0 | 3 |
| HES3 | GNB3 | 0.52773 | 3 | 0 | 3 |
For details and further investigation, click here
