| Full name: pyroglutamylated RFamide peptide | Alias Symbol: 26RFa|P518 | ||
| Type: protein-coding gene | Cytoband: 9q34.12 | ||
| Entrez ID: 347148 | HGNC ID: HGNC:29982 | Ensembl Gene: ENSG00000188710 | OMIM ID: 609795 |
| Drug and gene relationship at DGIdb | |||
Expression of QRFP:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE53622 | QRFP | 347148 | 38822 | 0.1630 | 0.0287 | |
| GSE53624 | QRFP | 347148 | 38822 | 0.1210 | 0.2463 | |
| GSE97050 | QRFP | 347148 | A_33_P3272080 | -0.1667 | 0.4522 | |
| SRP133303 | QRFP | 347148 | RNAseq | -1.5837 | 0.0000 | |
| TCGA | QRFP | 347148 | RNAseq | -1.0979 | 0.0091 |
Upregulated datasets: 0; Downregulated datasets: 2.
Survival by QRFP expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of QRFP:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | QRFP | 347148 | 6 | 9 | 15 | |
| GSE20123 | QRFP | 347148 | 6 | 9 | 15 | |
| GSE43470 | QRFP | 347148 | 5 | 7 | 31 | |
| GSE46452 | QRFP | 347148 | 6 | 13 | 40 | |
| GSE47630 | QRFP | 347148 | 3 | 16 | 21 | |
| GSE54993 | QRFP | 347148 | 3 | 3 | 64 | |
| GSE54994 | QRFP | 347148 | 12 | 9 | 32 | |
| GSE60625 | QRFP | 347148 | 0 | 0 | 11 | |
| GSE74703 | QRFP | 347148 | 5 | 5 | 26 | |
| GSE74704 | QRFP | 347148 | 3 | 7 | 10 | |
| TCGA | QRFP | 347148 | 27 | 26 | 43 |
Total number of gains: 76; Total number of losses: 104; Total Number of normals: 308.
Somatic mutations of QRFP:
Generating mutation plots.
Highly correlated genes for QRFP:
Showing top 20/22 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| QRFP | PKLR | 0.768401 | 3 | 0 | 3 |
| QRFP | SPACA3 | 0.762656 | 3 | 0 | 3 |
| QRFP | PTAFR | 0.761269 | 3 | 0 | 3 |
| QRFP | NPPB | 0.756333 | 3 | 0 | 3 |
| QRFP | GH1 | 0.75413 | 3 | 0 | 3 |
| QRFP | KRT35 | 0.75146 | 3 | 0 | 3 |
| QRFP | NTNG2 | 0.745815 | 3 | 0 | 3 |
| QRFP | ZNF329 | 0.738187 | 3 | 0 | 3 |
| QRFP | C19orf44 | 0.722878 | 3 | 0 | 3 |
| QRFP | C2CD4D | 0.720694 | 3 | 0 | 3 |
| QRFP | CELF5 | 0.718137 | 3 | 0 | 3 |
| QRFP | HMX3 | 0.707154 | 3 | 0 | 3 |
| QRFP | ANKRD33 | 0.701381 | 3 | 0 | 3 |
| QRFP | TRIM46 | 0.700287 | 3 | 0 | 3 |
| QRFP | SLC4A1 | 0.689745 | 3 | 0 | 3 |
| QRFP | PRDM13 | 0.676781 | 3 | 0 | 3 |
| QRFP | PRR7 | 0.674945 | 3 | 0 | 3 |
| QRFP | RAX2 | 0.672723 | 3 | 0 | 3 |
| QRFP | ZAN | 0.661415 | 3 | 0 | 3 |
| QRFP | EXOG | 0.647183 | 3 | 0 | 3 |
For details and further investigation, click here
