| Full name: keratin 35 | Alias Symbol: Ha-5 | ||
| Type: protein-coding gene | Cytoband: 17q21.2 | ||
| Entrez ID: 3886 | HGNC ID: HGNC:6453 | Ensembl Gene: ENSG00000197079 | OMIM ID: 602764 |
| Drug and gene relationship at DGIdb | |||
Expression of KRT35:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | KRT35 | 3886 | 216921_s_at | -0.1239 | 0.5431 | |
| GSE20347 | KRT35 | 3886 | 216921_s_at | -0.0300 | 0.6619 | |
| GSE23400 | KRT35 | 3886 | 216921_s_at | -0.1517 | 0.0001 | |
| GSE26886 | KRT35 | 3886 | 216921_s_at | 0.2139 | 0.0202 | |
| GSE29001 | KRT35 | 3886 | 216921_s_at | -0.1798 | 0.2731 | |
| GSE38129 | KRT35 | 3886 | 216921_s_at | -0.0683 | 0.2589 | |
| GSE45670 | KRT35 | 3886 | 216921_s_at | 0.0328 | 0.7091 | |
| GSE53622 | KRT35 | 3886 | 71950 | 0.3334 | 0.0001 | |
| GSE53624 | KRT35 | 3886 | 71950 | 0.0636 | 0.6353 | |
| GSE63941 | KRT35 | 3886 | 216921_s_at | -0.0264 | 0.8584 | |
| GSE77861 | KRT35 | 3886 | 216921_s_at | -0.0890 | 0.2211 | |
| GSE97050 | KRT35 | 3886 | A_23_P78201 | 0.3580 | 0.2272 | |
| SRP133303 | KRT35 | 3886 | RNAseq | -4.7885 | 0.0000 | |
| SRP159526 | KRT35 | 3886 | RNAseq | -6.8155 | 0.0000 | |
| TCGA | KRT35 | 3886 | RNAseq | 1.3888 | 0.2839 |
Upregulated datasets: 0; Downregulated datasets: 2.
Survival by KRT35 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of KRT35:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | KRT35 | 3886 | 6 | 2 | 22 | |
| GSE20123 | KRT35 | 3886 | 6 | 2 | 22 | |
| GSE43470 | KRT35 | 3886 | 1 | 2 | 40 | |
| GSE46452 | KRT35 | 3886 | 34 | 0 | 25 | |
| GSE47630 | KRT35 | 3886 | 8 | 1 | 31 | |
| GSE54993 | KRT35 | 3886 | 3 | 4 | 63 | |
| GSE54994 | KRT35 | 3886 | 8 | 5 | 40 | |
| GSE60625 | KRT35 | 3886 | 4 | 0 | 7 | |
| GSE74703 | KRT35 | 3886 | 1 | 1 | 34 | |
| GSE74704 | KRT35 | 3886 | 4 | 1 | 15 | |
| TCGA | KRT35 | 3886 | 23 | 7 | 66 |
Total number of gains: 98; Total number of losses: 25; Total Number of normals: 365.
Somatic mutations of KRT35:
Generating mutation plots.
Highly correlated genes for KRT35:
Showing top 20/943 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| KRT35 | OR5A1 | 0.789121 | 3 | 0 | 3 |
| KRT35 | OR2T1 | 0.783995 | 3 | 0 | 3 |
| KRT35 | KRT74 | 0.772387 | 4 | 0 | 4 |
| KRT35 | DEFB121 | 0.771433 | 3 | 0 | 3 |
| KRT35 | GALR2 | 0.768997 | 3 | 0 | 3 |
| KRT35 | TSKS | 0.758643 | 3 | 0 | 3 |
| KRT35 | DMC1 | 0.755436 | 3 | 0 | 3 |
| KRT35 | OR2T27 | 0.754905 | 3 | 0 | 3 |
| KRT35 | MRGPRG | 0.754185 | 3 | 0 | 3 |
| KRT35 | QRFP | 0.75146 | 3 | 0 | 3 |
| KRT35 | YY2 | 0.751287 | 3 | 0 | 3 |
| KRT35 | RASL10A | 0.748142 | 3 | 0 | 3 |
| KRT35 | KRTAP9-9 | 0.746414 | 3 | 0 | 3 |
| KRT35 | CDHR2 | 0.743199 | 5 | 0 | 4 |
| KRT35 | FMR1NB | 0.741336 | 3 | 0 | 3 |
| KRT35 | PLA2G2C | 0.737772 | 3 | 0 | 3 |
| KRT35 | MS4A18 | 0.736792 | 3 | 0 | 3 |
| KRT35 | DCDC1 | 0.731144 | 3 | 0 | 3 |
| KRT35 | FUT9 | 0.728927 | 3 | 0 | 3 |
| KRT35 | TAS2R30 | 0.72784 | 3 | 0 | 3 |
For details and further investigation, click here
