| Full name: pannexin 2 | Alias Symbol: hPANX2|PX2 | ||
| Type: protein-coding gene | Cytoband: 22q13.33 | ||
| Entrez ID: 56666 | HGNC ID: HGNC:8600 | Ensembl Gene: ENSG00000073150 | OMIM ID: 608421 |
| Drug and gene relationship at DGIdb | |||
Expression of PANX2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PANX2 | 56666 | 1552944_a_at | 0.0972 | 0.7999 | |
| GSE26886 | PANX2 | 56666 | 1552944_a_at | 0.1931 | 0.0965 | |
| GSE45670 | PANX2 | 56666 | 1552944_a_at | 0.1068 | 0.1981 | |
| GSE53622 | PANX2 | 56666 | 38620 | 0.2097 | 0.0134 | |
| GSE53624 | PANX2 | 56666 | 38620 | -0.1143 | 0.2010 | |
| GSE63941 | PANX2 | 56666 | 1552944_a_at | 0.6150 | 0.0075 | |
| GSE77861 | PANX2 | 56666 | 1552944_a_at | 0.1267 | 0.2559 | |
| GSE97050 | PANX2 | 56666 | A_24_P160202 | 0.1506 | 0.5089 | |
| SRP007169 | PANX2 | 56666 | RNAseq | 0.0289 | 0.9607 | |
| SRP064894 | PANX2 | 56666 | RNAseq | 0.4365 | 0.3509 | |
| SRP133303 | PANX2 | 56666 | RNAseq | 1.7218 | 0.0013 | |
| SRP159526 | PANX2 | 56666 | RNAseq | 1.8743 | 0.0004 | |
| SRP219564 | PANX2 | 56666 | RNAseq | 1.2385 | 0.1706 | |
| TCGA | PANX2 | 56666 | RNAseq | 1.6001 | 0.0000 |
Upregulated datasets: 3; Downregulated datasets: 0.
Survival by PANX2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PANX2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PANX2 | 56666 | 3 | 8 | 19 | |
| GSE20123 | PANX2 | 56666 | 3 | 8 | 19 | |
| GSE43470 | PANX2 | 56666 | 2 | 8 | 33 | |
| GSE46452 | PANX2 | 56666 | 31 | 2 | 26 | |
| GSE47630 | PANX2 | 56666 | 9 | 4 | 27 | |
| GSE54993 | PANX2 | 56666 | 4 | 6 | 60 | |
| GSE54994 | PANX2 | 56666 | 11 | 8 | 34 | |
| GSE60625 | PANX2 | 56666 | 5 | 0 | 6 | |
| GSE74703 | PANX2 | 56666 | 2 | 6 | 28 | |
| GSE74704 | PANX2 | 56666 | 1 | 4 | 15 | |
| TCGA | PANX2 | 56666 | 26 | 16 | 54 |
Total number of gains: 97; Total number of losses: 70; Total Number of normals: 321.
Somatic mutations of PANX2:
Generating mutation plots.
Highly correlated genes for PANX2:
Showing top 20/543 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PANX2 | KCTD19 | 0.82076 | 3 | 0 | 3 |
| PANX2 | SPACA3 | 0.760681 | 3 | 0 | 3 |
| PANX2 | STRC | 0.756932 | 3 | 0 | 3 |
| PANX2 | PRR7-AS1 | 0.739683 | 3 | 0 | 3 |
| PANX2 | ALPL | 0.736126 | 5 | 0 | 4 |
| PANX2 | IRF3 | 0.731909 | 3 | 0 | 3 |
| PANX2 | PTPRN | 0.731908 | 3 | 0 | 3 |
| PANX2 | C19orf44 | 0.717411 | 3 | 0 | 3 |
| PANX2 | ITIH3 | 0.706393 | 3 | 0 | 3 |
| PANX2 | FCER2 | 0.706239 | 3 | 0 | 3 |
| PANX2 | C9orf153 | 0.70394 | 3 | 0 | 3 |
| PANX2 | CNOT3 | 0.703721 | 5 | 0 | 5 |
| PANX2 | TMEM235 | 0.703418 | 4 | 0 | 4 |
| PANX2 | CSH1 | 0.702161 | 4 | 0 | 3 |
| PANX2 | OSGIN1 | 0.701858 | 5 | 0 | 5 |
| PANX2 | GPR35 | 0.701242 | 5 | 0 | 5 |
| PANX2 | SLC22A31 | 0.700631 | 3 | 0 | 3 |
| PANX2 | RIMBP2 | 0.69123 | 4 | 0 | 4 |
| PANX2 | GABRB3 | 0.687234 | 3 | 0 | 3 |
| PANX2 | IL17RC | 0.679301 | 3 | 0 | 3 |
For details and further investigation, click here
