LIPI

 

Full name: lipase I Alias Symbol: PRED5|LPDL|CT17|mPA-PLA1beta|PLA1C
Type: protein-coding gene Cytoband: 21q11.2
Entrez ID: 149998 HGNC ID: HGNC:18821 Ensembl Gene: ENSG00000188992 OMIM ID: 609252
Drug and gene relationship at DGIdb

 

Expression of LIPI:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 LIPI 149998 242178_at 0.0204 0.9363
GSE26886 LIPI 149998 242178_at -0.0872 0.3984
GSE45670 LIPI 149998 242178_at 0.0622 0.4594
GSE63941 LIPI 149998 242178_at 0.0668 0.5515
GSE77861 LIPI 149998 242178_at -0.0505 0.5515
GSE97050 LIPI 149998 A_23_P6201 -0.0182 0.9469
TCGA LIPI 149998 RNAseq 0.8783 0.2351

Upregulated datasets: 0; Downregulated datasets: 0.  

 

Survival by LIPI expression:

 

TCGA

 

Note: Click image to view full size file.  

Copy number change of LIPI:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 LIPI 149998 3 9 18
GSE20123 LIPI 149998 3 9 18
GSE43470 LIPI 149998 2 11 30
GSE46452 LIPI 149998 1 22 36
GSE47630 LIPI 149998 6 17 17
GSE54993 LIPI 149998 9 1 60
GSE54994 LIPI 149998 3 10 40
GSE60625 LIPI 149998 0 0 11
GSE74703 LIPI 149998 2 8 26
GSE74704 LIPI 149998 3 6 11
TCGA LIPI 149998 14 40 42

Total number of gains: 46; Total number of losses: 133; Total Number of normals: 309.  

 

Somatic mutations of LIPI:

 

Generating mutation plots.

 

Highly correlated genes for LIPI:

 

Showing all 11 correlated genes with mean PCC>0.5.

Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
LIPIAICDA0.714249303
LIPICALCA0.675022303
LIPIPGLYRP30.626633303
LIPIFCAMR0.62193303
LIPISLC22A160.598693303
LIPIPOU1F10.588172403
LIPICCR30.581981403
LIPISIRPD0.576055403
LIPILUZP40.547955303
LIPIFGA0.542097403
LIPISIGLEC50.505733403

For details and further investigation, click here