| Full name: activation induced cytidine deaminase | Alias Symbol: HIGM2|CDA2|ARP2|AID | ||
| Type: protein-coding gene | Cytoband: 12p13.31 | ||
| Entrez ID: 57379 | HGNC ID: HGNC:13203 | Ensembl Gene: ENSG00000111732 | OMIM ID: 605257 |
| Drug and gene relationship at DGIdb | |||
Expression of AICDA:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | AICDA | 57379 | 224499_s_at | 0.2203 | 0.6928 | |
| GSE20347 | AICDA | 57379 | 219841_at | 0.0258 | 0.7042 | |
| GSE23400 | AICDA | 57379 | 219841_at | -0.0895 | 0.0339 | |
| GSE26886 | AICDA | 57379 | 224499_s_at | 0.0701 | 0.5499 | |
| GSE29001 | AICDA | 57379 | 219841_at | -0.0651 | 0.6604 | |
| GSE38129 | AICDA | 57379 | 219841_at | -0.1096 | 0.0838 | |
| GSE45670 | AICDA | 57379 | 224499_s_at | 0.0445 | 0.7940 | |
| GSE53622 | AICDA | 57379 | 24025 | -0.0744 | 0.4041 | |
| GSE53624 | AICDA | 57379 | 24025 | -0.2671 | 0.0018 | |
| GSE63941 | AICDA | 57379 | 219841_at | -0.0323 | 0.8327 | |
| GSE77861 | AICDA | 57379 | 219841_at | -0.0507 | 0.5607 | |
| GSE97050 | AICDA | 57379 | A_23_P36641 | 0.1935 | 0.4389 | |
| SRP133303 | AICDA | 57379 | RNAseq | 0.2887 | 0.1174 | |
| SRP159526 | AICDA | 57379 | RNAseq | -1.4823 | 0.0723 | |
| SRP193095 | AICDA | 57379 | RNAseq | -0.1838 | 0.3241 | |
| SRP219564 | AICDA | 57379 | RNAseq | 0.4658 | 0.3073 | |
| TCGA | AICDA | 57379 | RNAseq | 1.0948 | 0.2744 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by AICDA expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of AICDA:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | AICDA | 57379 | 6 | 3 | 21 | |
| GSE20123 | AICDA | 57379 | 6 | 3 | 21 | |
| GSE43470 | AICDA | 57379 | 7 | 3 | 33 | |
| GSE46452 | AICDA | 57379 | 10 | 1 | 48 | |
| GSE47630 | AICDA | 57379 | 12 | 2 | 26 | |
| GSE54993 | AICDA | 57379 | 1 | 10 | 59 | |
| GSE54994 | AICDA | 57379 | 9 | 2 | 42 | |
| GSE60625 | AICDA | 57379 | 0 | 1 | 10 | |
| GSE74703 | AICDA | 57379 | 7 | 2 | 27 | |
| GSE74704 | AICDA | 57379 | 4 | 2 | 14 | |
| TCGA | AICDA | 57379 | 40 | 6 | 50 |
Total number of gains: 102; Total number of losses: 35; Total Number of normals: 351.
Somatic mutations of AICDA:
Generating mutation plots.
Highly correlated genes for AICDA:
Showing top 20/467 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| AICDA | OBSL1 | 0.817269 | 3 | 0 | 3 |
| AICDA | PAX3 | 0.794674 | 3 | 0 | 3 |
| AICDA | CPN1 | 0.761702 | 3 | 0 | 3 |
| AICDA | TULP2 | 0.759332 | 3 | 0 | 3 |
| AICDA | MAGEA8 | 0.758133 | 3 | 0 | 3 |
| AICDA | MYOD1 | 0.757087 | 3 | 0 | 3 |
| AICDA | MYBPH | 0.748077 | 3 | 0 | 3 |
| AICDA | SERINC5 | 0.746549 | 3 | 0 | 3 |
| AICDA | THPO | 0.73782 | 3 | 0 | 3 |
| AICDA | F2 | 0.73662 | 3 | 0 | 3 |
| AICDA | SLC22A7 | 0.733025 | 3 | 0 | 3 |
| AICDA | CLEC4M | 0.728887 | 3 | 0 | 3 |
| AICDA | FOLH1 | 0.728442 | 4 | 0 | 4 |
| AICDA | HRG | 0.727159 | 4 | 0 | 4 |
| AICDA | SV2C | 0.726569 | 3 | 0 | 3 |
| AICDA | CDX2 | 0.722003 | 3 | 0 | 3 |
| AICDA | CHTF8 | 0.71966 | 3 | 0 | 3 |
| AICDA | CALCR | 0.714686 | 4 | 0 | 4 |
| AICDA | SRPK3 | 0.714348 | 4 | 0 | 3 |
| AICDA | LIPI | 0.714249 | 3 | 0 | 3 |
For details and further investigation, click here
