| Full name: peptidoglycan recognition protein 3 | Alias Symbol: PGRPIA|PGLYRPIalpha|PGRP-Ialpha | ||
| Type: protein-coding gene | Cytoband: 1q21.3 | ||
| Entrez ID: 114771 | HGNC ID: HGNC:30014 | Ensembl Gene: ENSG00000159527 | OMIM ID: 608197 |
| Drug and gene relationship at DGIdb | |||
Expression of PGLYRP3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PGLYRP3 | 114771 | 1553059_at | -0.6857 | 0.3587 | |
| GSE26886 | PGLYRP3 | 114771 | 1553059_at | 0.0088 | 0.9294 | |
| GSE45670 | PGLYRP3 | 114771 | 1553059_at | 0.1497 | 0.1595 | |
| GSE53622 | PGLYRP3 | 114771 | 120434 | -1.6476 | 0.0002 | |
| GSE53624 | PGLYRP3 | 114771 | 120434 | -2.1477 | 0.0000 | |
| GSE63941 | PGLYRP3 | 114771 | 1553059_at | 0.0407 | 0.7606 | |
| GSE77861 | PGLYRP3 | 114771 | 1553059_at | -0.1611 | 0.4084 | |
| GSE97050 | PGLYRP3 | 114771 | A_23_P96899 | -0.0342 | 0.9699 | |
| SRP007169 | PGLYRP3 | 114771 | RNAseq | -3.3465 | 0.0000 | |
| SRP008496 | PGLYRP3 | 114771 | RNAseq | -2.7995 | 0.0000 | |
| SRP064894 | PGLYRP3 | 114771 | RNAseq | -2.2286 | 0.0000 | |
| SRP133303 | PGLYRP3 | 114771 | RNAseq | -2.2106 | 0.0000 | |
| SRP159526 | PGLYRP3 | 114771 | RNAseq | -1.1830 | 0.2716 | |
| TCGA | PGLYRP3 | 114771 | RNAseq | 1.2378 | 0.0018 |
Upregulated datasets: 1; Downregulated datasets: 6.
Survival by PGLYRP3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PGLYRP3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PGLYRP3 | 114771 | 14 | 0 | 16 | |
| GSE20123 | PGLYRP3 | 114771 | 14 | 0 | 16 | |
| GSE43470 | PGLYRP3 | 114771 | 6 | 2 | 35 | |
| GSE46452 | PGLYRP3 | 114771 | 2 | 1 | 56 | |
| GSE47630 | PGLYRP3 | 114771 | 15 | 0 | 25 | |
| GSE54993 | PGLYRP3 | 114771 | 0 | 4 | 66 | |
| GSE54994 | PGLYRP3 | 114771 | 16 | 0 | 37 | |
| GSE60625 | PGLYRP3 | 114771 | 0 | 0 | 11 | |
| GSE74703 | PGLYRP3 | 114771 | 6 | 1 | 29 | |
| GSE74704 | PGLYRP3 | 114771 | 7 | 0 | 13 | |
| TCGA | PGLYRP3 | 114771 | 39 | 2 | 55 |
Total number of gains: 119; Total number of losses: 10; Total Number of normals: 359.
Somatic mutations of PGLYRP3:
Generating mutation plots.
Highly correlated genes for PGLYRP3:
Showing top 20/559 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PGLYRP3 | ZNF750 | 0.890226 | 3 | 0 | 3 |
| PGLYRP3 | SPRR2D | 0.853937 | 3 | 0 | 3 |
| PGLYRP3 | SPRR2B | 0.835317 | 3 | 0 | 3 |
| PGLYRP3 | SPRR2E | 0.831027 | 3 | 0 | 3 |
| PGLYRP3 | SPRR2F | 0.82052 | 3 | 0 | 3 |
| PGLYRP3 | TMPRSS11D | 0.815517 | 4 | 0 | 4 |
| PGLYRP3 | SPRR2A | 0.81522 | 3 | 0 | 3 |
| PGLYRP3 | TGM1 | 0.80123 | 4 | 0 | 4 |
| PGLYRP3 | KLK11 | 0.798277 | 4 | 0 | 4 |
| PGLYRP3 | GRHL1 | 0.789882 | 4 | 0 | 4 |
| PGLYRP3 | SPRR1A | 0.787169 | 4 | 0 | 4 |
| PGLYRP3 | LY6D | 0.787145 | 3 | 0 | 3 |
| PGLYRP3 | CEACAM6 | 0.787045 | 3 | 0 | 3 |
| PGLYRP3 | NMU | 0.779156 | 3 | 0 | 3 |
| PGLYRP3 | SLPI | 0.779141 | 4 | 0 | 4 |
| PGLYRP3 | KLF5 | 0.775968 | 3 | 0 | 3 |
| PGLYRP3 | KRT75 | 0.76996 | 3 | 0 | 3 |
| PGLYRP3 | LCN2 | 0.768888 | 4 | 0 | 4 |
| PGLYRP3 | ARAP2 | 0.767478 | 3 | 0 | 3 |
| PGLYRP3 | TMEM40 | 0.765644 | 4 | 0 | 4 |
For details and further investigation, click here
