| Full name: POU class 1 homeobox 1 | Alias Symbol: GHF-1|POU1F1a|PIT-1 | ||
| Type: protein-coding gene | Cytoband: 3p11.2 | ||
| Entrez ID: 5449 | HGNC ID: HGNC:9210 | Ensembl Gene: ENSG00000064835 | OMIM ID: 173110 |
| Drug and gene relationship at DGIdb | |||
Expression of POU1F1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | POU1F1 | 5449 | 207846_at | -0.0354 | 0.8774 | |
| GSE20347 | POU1F1 | 5449 | 207846_at | -0.0428 | 0.3228 | |
| GSE23400 | POU1F1 | 5449 | 207846_at | -0.0235 | 0.0519 | |
| GSE26886 | POU1F1 | 5449 | 207846_at | 0.0768 | 0.3671 | |
| GSE29001 | POU1F1 | 5449 | 207846_at | -0.0988 | 0.3437 | |
| GSE38129 | POU1F1 | 5449 | 207846_at | -0.0003 | 0.9943 | |
| GSE45670 | POU1F1 | 5449 | 207846_at | 0.1177 | 0.7669 | |
| GSE53622 | POU1F1 | 5449 | 7635 | 0.0097 | 0.8803 | |
| GSE53624 | POU1F1 | 5449 | 7635 | 0.0879 | 0.2332 | |
| GSE63941 | POU1F1 | 5449 | 207846_at | 0.0231 | 0.8469 | |
| GSE77861 | POU1F1 | 5449 | 207846_at | 0.0301 | 0.7303 | |
| GSE97050 | POU1F1 | 5449 | A_23_P155539 | 0.0247 | 0.9133 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by POU1F1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of POU1F1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | POU1F1 | 5449 | 3 | 16 | 11 | |
| GSE20123 | POU1F1 | 5449 | 3 | 16 | 11 | |
| GSE43470 | POU1F1 | 5449 | 2 | 20 | 21 | |
| GSE46452 | POU1F1 | 5449 | 3 | 16 | 40 | |
| GSE47630 | POU1F1 | 5449 | 4 | 18 | 18 | |
| GSE54993 | POU1F1 | 5449 | 4 | 3 | 63 | |
| GSE54994 | POU1F1 | 5449 | 3 | 27 | 23 | |
| GSE60625 | POU1F1 | 5449 | 0 | 6 | 5 | |
| GSE74703 | POU1F1 | 5449 | 2 | 18 | 16 | |
| GSE74704 | POU1F1 | 5449 | 2 | 11 | 7 | |
| TCGA | POU1F1 | 5449 | 3 | 71 | 22 |
Total number of gains: 29; Total number of losses: 222; Total Number of normals: 237.
Somatic mutations of POU1F1:
Generating mutation plots.
Highly correlated genes for POU1F1:
Showing top 20/246 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| POU1F1 | OR5A1 | 0.809491 | 3 | 0 | 3 |
| POU1F1 | SLC5A5 | 0.802313 | 3 | 0 | 3 |
| POU1F1 | TESC | 0.789178 | 3 | 0 | 3 |
| POU1F1 | PTPRCAP | 0.78313 | 3 | 0 | 3 |
| POU1F1 | OR10W1 | 0.773675 | 3 | 0 | 3 |
| POU1F1 | C1QL2 | 0.771906 | 3 | 0 | 3 |
| POU1F1 | ADH6 | 0.762666 | 3 | 0 | 3 |
| POU1F1 | GRID2 | 0.749909 | 3 | 0 | 3 |
| POU1F1 | BSX | 0.740245 | 3 | 0 | 3 |
| POU1F1 | WAS | 0.739314 | 4 | 0 | 4 |
| POU1F1 | MYO1A | 0.73675 | 3 | 0 | 3 |
| POU1F1 | DNAH6 | 0.733066 | 3 | 0 | 3 |
| POU1F1 | FAM71F1 | 0.732528 | 3 | 0 | 3 |
| POU1F1 | IL9R | 0.731569 | 3 | 0 | 3 |
| POU1F1 | ZNF182 | 0.728998 | 3 | 0 | 3 |
| POU1F1 | OR4D1 | 0.727198 | 3 | 0 | 3 |
| POU1F1 | TTLL9 | 0.724487 | 4 | 0 | 3 |
| POU1F1 | CCDC33 | 0.721257 | 3 | 0 | 3 |
| POU1F1 | KCNA7 | 0.719863 | 3 | 0 | 3 |
| POU1F1 | LMF1 | 0.71402 | 3 | 0 | 3 |
For details and further investigation, click here
