| Full name: splicing factor 3b subunit 5 | Alias Symbol: SF3b10|MGC3133|Ysf3 | ||
| Type: protein-coding gene | Cytoband: 6q24.2 | ||
| Entrez ID: 83443 | HGNC ID: HGNC:21083 | Ensembl Gene: ENSG00000169976 | OMIM ID: 617847 |
| Drug and gene relationship at DGIdb | |||
Expression of SF3B5:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SF3B5 | 83443 | 221263_s_at | 0.1318 | 0.7999 | |
| GSE20347 | SF3B5 | 83443 | 221263_s_at | -0.1067 | 0.5942 | |
| GSE23400 | SF3B5 | 83443 | 221263_s_at | 0.0798 | 0.2983 | |
| GSE26886 | SF3B5 | 83443 | 221263_s_at | 0.4101 | 0.0318 | |
| GSE29001 | SF3B5 | 83443 | 221263_s_at | -0.1369 | 0.7279 | |
| GSE38129 | SF3B5 | 83443 | 221263_s_at | 0.1077 | 0.4451 | |
| GSE45670 | SF3B5 | 83443 | 221263_s_at | 0.0015 | 0.9903 | |
| GSE53622 | SF3B5 | 83443 | 148214 | -0.1815 | 0.0278 | |
| GSE53624 | SF3B5 | 83443 | 148214 | 0.0342 | 0.6639 | |
| GSE63941 | SF3B5 | 83443 | 221263_s_at | 0.4751 | 0.1643 | |
| GSE77861 | SF3B5 | 83443 | 221263_s_at | -0.1824 | 0.6190 | |
| GSE97050 | SF3B5 | 83443 | A_23_P19576 | 0.1176 | 0.5849 | |
| SRP007169 | SF3B5 | 83443 | RNAseq | -0.3139 | 0.4299 | |
| SRP008496 | SF3B5 | 83443 | RNAseq | -0.0833 | 0.7813 | |
| SRP064894 | SF3B5 | 83443 | RNAseq | 0.1800 | 0.5797 | |
| SRP133303 | SF3B5 | 83443 | RNAseq | 0.0774 | 0.5558 | |
| SRP159526 | SF3B5 | 83443 | RNAseq | 0.0748 | 0.6968 | |
| SRP193095 | SF3B5 | 83443 | RNAseq | -0.6556 | 0.0000 | |
| SRP219564 | SF3B5 | 83443 | RNAseq | -0.1958 | 0.5339 | |
| TCGA | SF3B5 | 83443 | RNAseq | 0.0267 | 0.6297 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by SF3B5 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SF3B5:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SF3B5 | 83443 | 2 | 4 | 24 | |
| GSE20123 | SF3B5 | 83443 | 2 | 3 | 25 | |
| GSE43470 | SF3B5 | 83443 | 5 | 0 | 38 | |
| GSE46452 | SF3B5 | 83443 | 3 | 10 | 46 | |
| GSE47630 | SF3B5 | 83443 | 9 | 4 | 27 | |
| GSE54993 | SF3B5 | 83443 | 3 | 2 | 65 | |
| GSE54994 | SF3B5 | 83443 | 8 | 8 | 37 | |
| GSE60625 | SF3B5 | 83443 | 0 | 1 | 10 | |
| GSE74703 | SF3B5 | 83443 | 4 | 0 | 32 | |
| GSE74704 | SF3B5 | 83443 | 0 | 1 | 19 | |
| TCGA | SF3B5 | 83443 | 12 | 19 | 65 |
Total number of gains: 48; Total number of losses: 52; Total Number of normals: 388.
Somatic mutations of SF3B5:
Generating mutation plots.
Highly correlated genes for SF3B5:
Showing top 20/325 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SF3B5 | NAIF1 | 0.740085 | 3 | 0 | 3 |
| SF3B5 | ZNF41 | 0.690746 | 3 | 0 | 3 |
| SF3B5 | FBXW9 | 0.687389 | 5 | 0 | 5 |
| SF3B5 | EIF2S3 | 0.684267 | 3 | 0 | 3 |
| SF3B5 | ZKSCAN4 | 0.678814 | 3 | 0 | 3 |
| SF3B5 | RPP38 | 0.675169 | 3 | 0 | 3 |
| SF3B5 | CHID1 | 0.669187 | 3 | 0 | 3 |
| SF3B5 | VAMP7 | 0.663415 | 4 | 0 | 4 |
| SF3B5 | VRK3 | 0.649478 | 4 | 0 | 4 |
| SF3B5 | ZBTB22 | 0.646835 | 3 | 0 | 3 |
| SF3B5 | UBE2J2 | 0.640646 | 5 | 0 | 5 |
| SF3B5 | GOLGA7 | 0.637558 | 3 | 0 | 3 |
| SF3B5 | BEX5 | 0.634774 | 4 | 0 | 3 |
| SF3B5 | CLPP | 0.631213 | 9 | 0 | 7 |
| SF3B5 | CCDC97 | 0.630959 | 3 | 0 | 3 |
| SF3B5 | VGLL4 | 0.629827 | 3 | 0 | 3 |
| SF3B5 | MAD2L2 | 0.62938 | 3 | 0 | 3 |
| SF3B5 | TRAPPC2L | 0.624286 | 8 | 0 | 6 |
| SF3B5 | C12orf10 | 0.619175 | 8 | 0 | 6 |
| SF3B5 | PIN1 | 0.616315 | 7 | 0 | 6 |
For details and further investigation, click here
