| Full name: zinc finger and BTB domain containing 22 | Alias Symbol: BING1|ZNF297A|fruitless|fru|ZBTB22A | ||
| Type: protein-coding gene | Cytoband: 6p21.3 | ||
| Entrez ID: 9278 | HGNC ID: HGNC:13085 | Ensembl Gene: ENSG00000236104 | OMIM ID: 611439 |
| Drug and gene relationship at DGIdb | |||
Expression of ZBTB22:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ZBTB22 | 9278 | 213081_at | 0.1196 | 0.7140 | |
| GSE20347 | ZBTB22 | 9278 | 213081_at | -0.0827 | 0.3628 | |
| GSE23400 | ZBTB22 | 9278 | 213081_at | -0.0306 | 0.4643 | |
| GSE26886 | ZBTB22 | 9278 | 213081_at | -0.0136 | 0.9189 | |
| GSE29001 | ZBTB22 | 9278 | 213081_at | -0.3415 | 0.0974 | |
| GSE38129 | ZBTB22 | 9278 | 213081_at | -0.0766 | 0.3025 | |
| GSE45670 | ZBTB22 | 9278 | 213081_at | -0.1027 | 0.3172 | |
| GSE53622 | ZBTB22 | 9278 | 32192 | -0.1826 | 0.0028 | |
| GSE53624 | ZBTB22 | 9278 | 32192 | 0.0519 | 0.3519 | |
| GSE63941 | ZBTB22 | 9278 | 213081_at | 0.1312 | 0.4544 | |
| GSE77861 | ZBTB22 | 9278 | 213081_at | -0.1122 | 0.3535 | |
| GSE97050 | ZBTB22 | 9278 | A_23_P111188 | -0.1856 | 0.5282 | |
| SRP007169 | ZBTB22 | 9278 | RNAseq | -0.6858 | 0.0957 | |
| SRP008496 | ZBTB22 | 9278 | RNAseq | -0.3878 | 0.2605 | |
| SRP064894 | ZBTB22 | 9278 | RNAseq | 0.0478 | 0.7997 | |
| SRP133303 | ZBTB22 | 9278 | RNAseq | -0.3167 | 0.1083 | |
| SRP159526 | ZBTB22 | 9278 | RNAseq | -0.1822 | 0.2529 | |
| SRP193095 | ZBTB22 | 9278 | RNAseq | -0.1503 | 0.1692 | |
| SRP219564 | ZBTB22 | 9278 | RNAseq | -0.0889 | 0.6926 | |
| TCGA | ZBTB22 | 9278 | RNAseq | 0.0173 | 0.7595 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by ZBTB22 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ZBTB22:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ZBTB22 | 9278 | 5 | 0 | 25 | |
| GSE20123 | ZBTB22 | 9278 | 5 | 0 | 25 | |
| GSE43470 | ZBTB22 | 9278 | 4 | 1 | 38 | |
| GSE46452 | ZBTB22 | 9278 | 2 | 9 | 48 | |
| GSE47630 | ZBTB22 | 9278 | 8 | 4 | 28 | |
| GSE54993 | ZBTB22 | 9278 | 3 | 1 | 66 | |
| GSE54994 | ZBTB22 | 9278 | 11 | 4 | 38 | |
| GSE60625 | ZBTB22 | 9278 | 1 | 0 | 10 | |
| GSE74703 | ZBTB22 | 9278 | 4 | 0 | 32 | |
| GSE74704 | ZBTB22 | 9278 | 2 | 0 | 18 | |
| TCGA | ZBTB22 | 9278 | 15 | 16 | 65 |
Total number of gains: 60; Total number of losses: 35; Total Number of normals: 393.
Somatic mutations of ZBTB22:
Generating mutation plots.
Highly correlated genes for ZBTB22:
Showing top 20/338 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ZBTB22 | CABIN1 | 0.824208 | 3 | 0 | 3 |
| ZBTB22 | ZNF784 | 0.804383 | 3 | 0 | 3 |
| ZBTB22 | TPSG1 | 0.794584 | 3 | 0 | 3 |
| ZBTB22 | ARAF | 0.764553 | 4 | 0 | 4 |
| ZBTB22 | C11orf49 | 0.758994 | 3 | 0 | 3 |
| ZBTB22 | ARRB1 | 0.753186 | 3 | 0 | 3 |
| ZBTB22 | GORASP1 | 0.753083 | 3 | 0 | 3 |
| ZBTB22 | GRWD1 | 0.753039 | 3 | 0 | 3 |
| ZBTB22 | CIDEC | 0.737952 | 4 | 0 | 4 |
| ZBTB22 | PRKACA | 0.730918 | 4 | 0 | 3 |
| ZBTB22 | NPFF | 0.72969 | 3 | 0 | 3 |
| ZBTB22 | ILK | 0.71611 | 3 | 0 | 3 |
| ZBTB22 | MUL1 | 0.708359 | 3 | 0 | 3 |
| ZBTB22 | KCTD13 | 0.702311 | 3 | 0 | 3 |
| ZBTB22 | DCP1A | 0.70028 | 3 | 0 | 3 |
| ZBTB22 | TSNARE1 | 0.699444 | 3 | 0 | 3 |
| ZBTB22 | DMWD | 0.695041 | 4 | 0 | 3 |
| ZBTB22 | NUCB1 | 0.690217 | 5 | 0 | 4 |
| ZBTB22 | SPTAN1 | 0.689573 | 3 | 0 | 3 |
| ZBTB22 | KCNAB2 | 0.684948 | 3 | 0 | 3 |
For details and further investigation, click here
