| Full name: ubiquitin conjugating enzyme E2 J2 | Alias Symbol: Ubc6p|NCUBE2 | ||
| Type: protein-coding gene | Cytoband: 1p36.33 | ||
| Entrez ID: 118424 | HGNC ID: HGNC:19268 | Ensembl Gene: ENSG00000160087 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
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Expression of UBE2J2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | UBE2J2 | 118424 | 225209_s_at | 0.3729 | 0.3296 | |
| GSE26886 | UBE2J2 | 118424 | 225209_s_at | 0.4324 | 0.0117 | |
| GSE45670 | UBE2J2 | 118424 | 225209_s_at | 0.3025 | 0.0082 | |
| GSE53622 | UBE2J2 | 118424 | 60443 | -0.0194 | 0.8179 | |
| GSE53624 | UBE2J2 | 118424 | 60443 | -0.0226 | 0.7486 | |
| GSE63941 | UBE2J2 | 118424 | 225209_s_at | 0.0947 | 0.7896 | |
| GSE77861 | UBE2J2 | 118424 | 225209_s_at | 0.0717 | 0.6774 | |
| GSE97050 | UBE2J2 | 118424 | A_33_P3310696 | 0.5480 | 0.1316 | |
| SRP007169 | UBE2J2 | 118424 | RNAseq | -1.0181 | 0.0028 | |
| SRP008496 | UBE2J2 | 118424 | RNAseq | -0.7116 | 0.0015 | |
| SRP064894 | UBE2J2 | 118424 | RNAseq | 0.4216 | 0.0791 | |
| SRP133303 | UBE2J2 | 118424 | RNAseq | 0.2238 | 0.1610 | |
| SRP159526 | UBE2J2 | 118424 | RNAseq | 0.1701 | 0.5621 | |
| SRP193095 | UBE2J2 | 118424 | RNAseq | 0.1333 | 0.1535 | |
| SRP219564 | UBE2J2 | 118424 | RNAseq | -0.0386 | 0.9041 | |
| TCGA | UBE2J2 | 118424 | RNAseq | 0.0549 | 0.2839 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by UBE2J2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of UBE2J2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | UBE2J2 | 118424 | 3 | 7 | 20 | |
| GSE20123 | UBE2J2 | 118424 | 3 | 6 | 21 | |
| GSE43470 | UBE2J2 | 118424 | 3 | 5 | 35 | |
| GSE46452 | UBE2J2 | 118424 | 7 | 1 | 51 | |
| GSE47630 | UBE2J2 | 118424 | 8 | 4 | 28 | |
| GSE54993 | UBE2J2 | 118424 | 2 | 2 | 66 | |
| GSE54994 | UBE2J2 | 118424 | 15 | 2 | 36 | |
| GSE60625 | UBE2J2 | 118424 | 0 | 0 | 11 | |
| GSE74703 | UBE2J2 | 118424 | 3 | 3 | 30 | |
| GSE74704 | UBE2J2 | 118424 | 3 | 0 | 17 | |
| TCGA | UBE2J2 | 118424 | 14 | 20 | 62 |
Total number of gains: 61; Total number of losses: 50; Total Number of normals: 377.
Somatic mutations of UBE2J2:
Generating mutation plots.
Highly correlated genes for UBE2J2:
Showing top 20/672 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| UBE2J2 | RRBP1 | 0.808261 | 3 | 0 | 3 |
| UBE2J2 | ACTL6A | 0.795443 | 3 | 0 | 3 |
| UBE2J2 | TMEM44 | 0.771325 | 3 | 0 | 3 |
| UBE2J2 | POGLUT1 | 0.75937 | 3 | 0 | 3 |
| UBE2J2 | MRPS30 | 0.752907 | 3 | 0 | 3 |
| UBE2J2 | TRAP1 | 0.750765 | 3 | 0 | 3 |
| UBE2J2 | SMARCD1 | 0.746202 | 3 | 0 | 3 |
| UBE2J2 | NADSYN1 | 0.741877 | 3 | 0 | 3 |
| UBE2J2 | TDG | 0.734904 | 3 | 0 | 3 |
| UBE2J2 | MKI67 | 0.733563 | 3 | 0 | 3 |
| UBE2J2 | SND1 | 0.731646 | 3 | 0 | 3 |
| UBE2J2 | PRPF4 | 0.731332 | 3 | 0 | 3 |
| UBE2J2 | CASP2 | 0.726855 | 3 | 0 | 3 |
| UBE2J2 | VMA21 | 0.725209 | 3 | 0 | 3 |
| UBE2J2 | NCLN | 0.724058 | 3 | 0 | 3 |
| UBE2J2 | ABCF1 | 0.717436 | 3 | 0 | 3 |
| UBE2J2 | BCL2L1 | 0.715121 | 4 | 0 | 3 |
| UBE2J2 | WRN | 0.712962 | 3 | 0 | 3 |
| UBE2J2 | STARD3 | 0.712484 | 3 | 0 | 3 |
| UBE2J2 | NPHP4 | 0.711146 | 5 | 0 | 5 |
For details and further investigation, click here
