| Full name: F-box and WD repeat domain containing 9 | Alias Symbol: MGC10870|Fbw9|MEC-15 | ||
| Type: protein-coding gene | Cytoband: 19p13.13 | ||
| Entrez ID: 84261 | HGNC ID: HGNC:28136 | Ensembl Gene: ENSG00000132004 | OMIM ID: 609074 |
| Drug and gene relationship at DGIdb | |||
Expression of FBXW9:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | FBXW9 | 84261 | 223419_at | 0.1482 | 0.8780 | |
| GSE26886 | FBXW9 | 84261 | 223419_at | 0.4922 | 0.0015 | |
| GSE45670 | FBXW9 | 84261 | 223419_at | 0.1261 | 0.2360 | |
| GSE53622 | FBXW9 | 84261 | 46263 | -0.1523 | 0.0617 | |
| GSE53624 | FBXW9 | 84261 | 46263 | 0.0771 | 0.4274 | |
| GSE63941 | FBXW9 | 84261 | 223419_at | 0.3588 | 0.3985 | |
| GSE77861 | FBXW9 | 84261 | 223419_at | -0.0731 | 0.6067 | |
| GSE97050 | FBXW9 | 84261 | A_23_P16214 | -0.1834 | 0.4885 | |
| SRP007169 | FBXW9 | 84261 | RNAseq | -0.6265 | 0.1099 | |
| SRP008496 | FBXW9 | 84261 | RNAseq | -0.5443 | 0.0343 | |
| SRP064894 | FBXW9 | 84261 | RNAseq | 0.5589 | 0.0669 | |
| SRP133303 | FBXW9 | 84261 | RNAseq | -0.1082 | 0.4991 | |
| SRP159526 | FBXW9 | 84261 | RNAseq | -0.0212 | 0.9469 | |
| SRP193095 | FBXW9 | 84261 | RNAseq | -0.2904 | 0.0216 | |
| SRP219564 | FBXW9 | 84261 | RNAseq | 0.5905 | 0.1935 | |
| TCGA | FBXW9 | 84261 | RNAseq | 0.2667 | 0.0013 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by FBXW9 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of FBXW9:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | FBXW9 | 84261 | 4 | 2 | 24 | |
| GSE20123 | FBXW9 | 84261 | 3 | 1 | 26 | |
| GSE43470 | FBXW9 | 84261 | 2 | 6 | 35 | |
| GSE46452 | FBXW9 | 84261 | 47 | 1 | 11 | |
| GSE47630 | FBXW9 | 84261 | 4 | 7 | 29 | |
| GSE54993 | FBXW9 | 84261 | 16 | 3 | 51 | |
| GSE54994 | FBXW9 | 84261 | 6 | 13 | 34 | |
| GSE60625 | FBXW9 | 84261 | 9 | 0 | 2 | |
| GSE74703 | FBXW9 | 84261 | 2 | 4 | 30 | |
| GSE74704 | FBXW9 | 84261 | 0 | 1 | 19 | |
| TCGA | FBXW9 | 84261 | 16 | 13 | 67 |
Total number of gains: 109; Total number of losses: 51; Total Number of normals: 328.
Somatic mutations of FBXW9:
Generating mutation plots.
Highly correlated genes for FBXW9:
Showing top 20/316 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| FBXW9 | PIN1 | 0.802841 | 4 | 0 | 4 |
| FBXW9 | MRI1 | 0.792592 | 3 | 0 | 3 |
| FBXW9 | MRPS18A | 0.780136 | 3 | 0 | 3 |
| FBXW9 | UBL5 | 0.770729 | 4 | 0 | 4 |
| FBXW9 | LSP1 | 0.754625 | 3 | 0 | 3 |
| FBXW9 | DNASE2 | 0.736662 | 4 | 0 | 4 |
| FBXW9 | UBE2NL | 0.733673 | 3 | 0 | 3 |
| FBXW9 | NACC1 | 0.727383 | 4 | 0 | 4 |
| FBXW9 | PLEKHJ1 | 0.715658 | 3 | 0 | 3 |
| FBXW9 | GCC1 | 0.711928 | 4 | 0 | 4 |
| FBXW9 | SMC3 | 0.711746 | 3 | 0 | 3 |
| FBXW9 | C12orf10 | 0.71093 | 3 | 0 | 3 |
| FBXW9 | C1orf50 | 0.707253 | 4 | 0 | 3 |
| FBXW9 | C1orf122 | 0.702661 | 4 | 0 | 3 |
| FBXW9 | TEX261 | 0.700531 | 3 | 0 | 3 |
| FBXW9 | CAMTA1 | 0.700501 | 3 | 0 | 3 |
| FBXW9 | JTB | 0.698538 | 3 | 0 | 3 |
| FBXW9 | PIGU | 0.697345 | 3 | 0 | 3 |
| FBXW9 | MPND | 0.696439 | 3 | 0 | 3 |
| FBXW9 | HCCS | 0.69597 | 4 | 0 | 3 |
For details and further investigation, click here
