SLC16A3

 

Full name: solute carrier family 16 member 3 Alias Symbol: MCT3|MCT4
Type: protein-coding gene Cytoband: 17q25.3
Entrez ID: 9123 HGNC ID: HGNC:10924 Ensembl Gene: ENSG00000141526 OMIM ID: 603877
Drug and gene relationship at DGIdb

 

Expression of SLC16A3:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE53622 SLC16A3 9123 27166 0.5314 0.0000
GSE53624 SLC16A3 9123 27166 0.5216 0.0000
GSE97050 SLC16A3 9123 A_23_P158725 0.7068 0.1529
SRP007169 SLC16A3 9123 RNAseq 0.5760 0.2938
SRP008496 SLC16A3 9123 RNAseq 0.2245 0.4994
SRP064894 SLC16A3 9123 RNAseq 0.9376 0.0011
SRP133303 SLC16A3 9123 RNAseq 1.2660 0.0000
SRP159526 SLC16A3 9123 RNAseq 0.0198 0.9445
SRP193095 SLC16A3 9123 RNAseq 0.5290 0.0443
SRP219564 SLC16A3 9123 RNAseq 0.9631 0.0596
TCGA SLC16A3 9123 RNAseq 0.3683 0.0000

Upregulated datasets: 1; Downregulated datasets: 0.  

 

Survival by SLC16A3 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of SLC16A3:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 SLC16A3 9123 4 5 21
GSE20123 SLC16A3 9123 4 5 21
GSE43470 SLC16A3 9123 3 5 35
GSE46452 SLC16A3 9123 34 0 25
GSE47630 SLC16A3 9123 9 2 29
GSE54993 SLC16A3 9123 2 5 63
GSE54994 SLC16A3 9123 10 6 37
GSE60625 SLC16A3 9123 6 0 5
GSE74703 SLC16A3 9123 3 3 30
GSE74704 SLC16A3 9123 4 4 12
TCGA SLC16A3 9123 24 13 59

Total number of gains: 103; Total number of losses: 48; Total Number of normals: 337.  

 

Somatic mutations of SLC16A3:

 

Generating mutation plots.

 

Highly correlated genes for SLC16A3:

 

Showing all 9 correlated genes with mean PCC>0.5.

Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
SLC16A3LIMK10.676089303
SLC16A3ITGB40.667733303
SLC16A3UBTD10.667542303
SLC16A3TMEM1890.666188303
SLC16A3PDP10.657194303
SLC16A3NAGS0.651608303
SLC16A3LMF20.623201303
SLC16A3C16orf740.600358303
SLC16A3PIEZO10.563615303

For details and further investigation, click here