| Full name: piezo type mechanosensitive ion channel component 1 | Alias Symbol: KIAA0233 | ||
| Type: protein-coding gene | Cytoband: 16q24.3 | ||
| Entrez ID: 9780 | HGNC ID: HGNC:28993 | Ensembl Gene: ENSG00000103335 | OMIM ID: 611184 |
| Drug and gene relationship at DGIdb | |||
Expression of PIEZO1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PIEZO1 | 9780 | 202771_at | 0.8329 | 0.2460 | |
| GSE20347 | PIEZO1 | 9780 | 202771_at | 0.5752 | 0.0040 | |
| GSE23400 | PIEZO1 | 9780 | 202771_at | 0.3432 | 0.0005 | |
| GSE26886 | PIEZO1 | 9780 | 202771_at | 0.4377 | 0.1088 | |
| GSE29001 | PIEZO1 | 9780 | 202771_at | 0.3697 | 0.4229 | |
| GSE38129 | PIEZO1 | 9780 | 202771_at | 0.5306 | 0.0017 | |
| GSE45670 | PIEZO1 | 9780 | 202771_at | 0.3427 | 0.0923 | |
| GSE53622 | PIEZO1 | 9780 | 41799 | 0.3834 | 0.0001 | |
| GSE53624 | PIEZO1 | 9780 | 41799 | 0.4407 | 0.0000 | |
| GSE63941 | PIEZO1 | 9780 | 202771_at | -0.4319 | 0.4833 | |
| GSE77861 | PIEZO1 | 9780 | 202771_at | 0.9222 | 0.0006 | |
| GSE97050 | PIEZO1 | A_19_P00802413 | -0.0267 | 0.9214 | ||
| SRP007169 | PIEZO1 | 9780 | RNAseq | 0.1473 | 0.7958 | |
| SRP008496 | PIEZO1 | 9780 | RNAseq | 0.0811 | 0.7971 | |
| SRP064894 | PIEZO1 | 9780 | RNAseq | 0.3188 | 0.0913 | |
| SRP133303 | PIEZO1 | 9780 | RNAseq | 0.6381 | 0.0021 | |
| SRP159526 | PIEZO1 | 9780 | RNAseq | 0.1452 | 0.5202 | |
| SRP193095 | PIEZO1 | 9780 | RNAseq | 0.7482 | 0.0000 | |
| SRP219564 | PIEZO1 | 9780 | RNAseq | 0.1084 | 0.7262 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by PIEZO1 expression:
 |  |
| GSE53622 | GSE53624 |
Note: Click image to view full size file.
Copy number change of PIEZO1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PIEZO1 | 9780 | 4 | 3 | 23 | |
| GSE20123 | PIEZO1 | 9780 | 4 | 3 | 23 | |
| GSE43470 | PIEZO1 | 9780 | 1 | 13 | 29 | |
| GSE46452 | PIEZO1 | 9780 | 38 | 1 | 20 | |
| GSE47630 | PIEZO1 | 9780 | 11 | 9 | 20 | |
| GSE54993 | PIEZO1 | 9780 | 3 | 4 | 63 | |
| GSE54994 | PIEZO1 | 9780 | 9 | 11 | 33 | |
| GSE60625 | PIEZO1 | 9780 | 4 | 0 | 7 | |
| GSE74703 | PIEZO1 | 9780 | 1 | 9 | 26 | |
| GSE74704 | PIEZO1 | 9780 | 3 | 2 | 15 | |
| TCGA | PIEZO1 | 9780 | 28 | 15 | 53 |
Total number of gains: 106; Total number of losses: 70; Total Number of normals: 312.
Somatic mutations of PIEZO1:
Generating mutation plots.
Highly correlated genes for PIEZO1:
Showing top 20/823 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PIEZO1 | TNPO1 | 0.777813 | 4 | 0 | 4 |
| PIEZO1 | OSGEP | 0.762631 | 3 | 0 | 3 |
| PIEZO1 | RLIM | 0.760154 | 3 | 0 | 3 |
| PIEZO1 | A1BG | 0.748859 | 3 | 0 | 3 |
| PIEZO1 | NEDD1 | 0.73979 | 3 | 0 | 3 |
| PIEZO1 | FANCL | 0.735523 | 3 | 0 | 3 |
| PIEZO1 | IL6R | 0.72823 | 3 | 0 | 3 |
| PIEZO1 | CHD3 | 0.727968 | 3 | 0 | 3 |
| PIEZO1 | PRPSAP2 | 0.725495 | 3 | 0 | 3 |
| PIEZO1 | DNAH14 | 0.723923 | 4 | 0 | 3 |
| PIEZO1 | TMC8 | 0.720591 | 3 | 0 | 3 |
| PIEZO1 | TRADD | 0.719997 | 5 | 0 | 4 |
| PIEZO1 | NACC1 | 0.714919 | 3 | 0 | 3 |
| PIEZO1 | SIX5 | 0.713397 | 4 | 0 | 3 |
| PIEZO1 | NFATC4 | 0.711247 | 3 | 0 | 3 |
| PIEZO1 | ABCC1 | 0.709814 | 3 | 0 | 3 |
| PIEZO1 | FLVCR1 | 0.703324 | 3 | 0 | 3 |
| PIEZO1 | SLC25A37 | 0.702773 | 4 | 0 | 3 |
| PIEZO1 | MLXIP | 0.701939 | 4 | 0 | 4 |
| PIEZO1 | HAX1 | 0.700977 | 4 | 0 | 3 |
For details and further investigation, click here
