| Full name: chromosome 16 open reading frame 74 | Alias Symbol: MGC17624 | ||
| Type: protein-coding gene | Cytoband: 16q24.1 | ||
| Entrez ID: 404550 | HGNC ID: HGNC:23362 | Ensembl Gene: ENSG00000154102 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of C16orf74:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | C16orf74 | 404550 | 227806_at | 1.3671 | 0.0642 | |
| GSE26886 | C16orf74 | 404550 | 227806_at | 0.9165 | 0.0000 | |
| GSE45670 | C16orf74 | 404550 | 227806_at | 0.7545 | 0.0034 | |
| GSE53622 | C16orf74 | 404550 | 8063 | 1.6562 | 0.0000 | |
| GSE53624 | C16orf74 | 404550 | 8063 | 2.1152 | 0.0000 | |
| GSE63941 | C16orf74 | 404550 | 227806_at | 0.7976 | 0.1699 | |
| GSE77861 | C16orf74 | 404550 | 227806_at | 0.3486 | 0.0791 | |
| GSE97050 | C16orf74 | 404550 | A_24_P289178 | 0.5499 | 0.1267 | |
| SRP007169 | C16orf74 | 404550 | RNAseq | 2.3385 | 0.0007 | |
| SRP064894 | C16orf74 | 404550 | RNAseq | 2.2298 | 0.0000 | |
| SRP133303 | C16orf74 | 404550 | RNAseq | 1.9291 | 0.0000 | |
| SRP159526 | C16orf74 | 404550 | RNAseq | 2.1274 | 0.0001 | |
| SRP193095 | C16orf74 | 404550 | RNAseq | 2.3580 | 0.0000 | |
| SRP219564 | C16orf74 | 404550 | RNAseq | 2.1969 | 0.0000 | |
| TCGA | C16orf74 | 404550 | RNAseq | 1.1299 | 0.0000 |
Upregulated datasets: 9; Downregulated datasets: 0.
Survival by C16orf74 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of C16orf74:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | C16orf74 | 404550 | 4 | 4 | 22 | |
| GSE20123 | C16orf74 | 404550 | 4 | 4 | 22 | |
| GSE43470 | C16orf74 | 404550 | 2 | 10 | 31 | |
| GSE46452 | C16orf74 | 404550 | 37 | 2 | 20 | |
| GSE47630 | C16orf74 | 404550 | 11 | 9 | 20 | |
| GSE54993 | C16orf74 | 404550 | 3 | 4 | 63 | |
| GSE54994 | C16orf74 | 404550 | 9 | 10 | 34 | |
| GSE60625 | C16orf74 | 404550 | 4 | 0 | 7 | |
| GSE74703 | C16orf74 | 404550 | 1 | 7 | 28 | |
| GSE74704 | C16orf74 | 404550 | 3 | 2 | 15 | |
| TCGA | C16orf74 | 404550 | 26 | 17 | 53 |
Total number of gains: 104; Total number of losses: 69; Total Number of normals: 315.
Somatic mutations of C16orf74:
Generating mutation plots.
Highly correlated genes for C16orf74:
Showing top 20/1586 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| C16orf74 | STC2 | 0.784878 | 7 | 0 | 7 |
| C16orf74 | EFNB1 | 0.761617 | 5 | 0 | 5 |
| C16orf74 | DKC1 | 0.758768 | 3 | 0 | 3 |
| C16orf74 | USB1 | 0.757888 | 6 | 0 | 6 |
| C16orf74 | GPRIN1 | 0.748245 | 5 | 0 | 5 |
| C16orf74 | GALNS | 0.741116 | 6 | 0 | 6 |
| C16orf74 | GINS4 | 0.740567 | 4 | 0 | 4 |
| C16orf74 | HOMER3 | 0.738157 | 6 | 0 | 6 |
| C16orf74 | FAM89A | 0.736619 | 3 | 0 | 3 |
| C16orf74 | DLX2 | 0.73612 | 3 | 0 | 3 |
| C16orf74 | WDR54 | 0.732998 | 7 | 0 | 7 |
| C16orf74 | AUP1 | 0.728077 | 7 | 0 | 7 |
| C16orf74 | STEAP1B | 0.726252 | 4 | 0 | 4 |
| C16orf74 | PTRH2 | 0.713361 | 7 | 0 | 6 |
| C16orf74 | NTMT1 | 0.712364 | 6 | 0 | 6 |
| C16orf74 | UBA5 | 0.711367 | 3 | 0 | 3 |
| C16orf74 | TMEM223 | 0.710963 | 5 | 0 | 5 |
| C16orf74 | RPL39L | 0.706975 | 7 | 0 | 7 |
| C16orf74 | XPR1 | 0.705436 | 7 | 0 | 6 |
| C16orf74 | KIAA0930 | 0.704258 | 7 | 0 | 7 |
For details and further investigation, click here
