SMCO3

 

Full name: single-pass membrane protein with coiled-coil domains 3 Alias Symbol: LOC440087
Type: protein-coding gene Cytoband: 12p12.3
Entrez ID: 440087 HGNC ID: HGNC:34401 Ensembl Gene: ENSG00000179256 OMIM ID: 
Drug and gene relationship at DGIdb

 

Expression of SMCO3:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 SMCO3 440087 237484_at -0.0348 0.8991
GSE26886 SMCO3 440087 237484_at 0.1629 0.1116
GSE45670 SMCO3 440087 237484_at -0.0122 0.9179
GSE53622 SMCO3 440087 17325 -0.0212 0.8591
GSE53624 SMCO3 440087 17325 0.2473 0.0084
GSE63941 SMCO3 440087 237484_at -0.6059 0.0385
GSE77861 SMCO3 440087 237484_at -0.1075 0.3415

Upregulated datasets: 0; Downregulated datasets: 0.  

 

Survival by SMCO3 expression:

 

GSE53622GSE53624

 

Note: Click image to view full size file.  

Copy number change of SMCO3:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 SMCO3 440087 6 2 22
GSE20123 SMCO3 440087 6 2 22
GSE43470 SMCO3 440087 9 4 30
GSE46452 SMCO3 440087 10 1 48
GSE47630 SMCO3 440087 14 1 25
GSE54993 SMCO3 440087 1 9 60
GSE54994 SMCO3 440087 10 2 41
GSE60625 SMCO3 440087 0 1 10
GSE74703 SMCO3 440087 9 3 24
GSE74704 SMCO3 440087 4 1 15
TCGA SMCO3 440087 41 5 50

Total number of gains: 110; Total number of losses: 31; Total Number of normals: 347.  

 

Somatic mutations of SMCO3:

 

Generating mutation plots.

 

Highly correlated genes for SMCO3:

 

Showing all 11 correlated genes with mean PCC>0.5.

Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
SMCO3ADCY80.650248303
SMCO3MSMO10.638999303
SMCO3RPS6KA2-AS10.623553303
SMCO3INS0.613709303
SMCO3METRNL0.609191303
SMCO3CCL70.601805303
SMCO3ATP1A30.601188303
SMCO3VWCE0.576897303
SMCO3SPATA90.572502403
SMCO3CBLN20.567067303
SMCO3TNNI30.538819303

For details and further investigation, click here