| Full name: meteorin like, glial cell differentiation regulator | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 17q25.3 | ||
| Entrez ID: 284207 | HGNC ID: HGNC:27584 | Ensembl Gene: ENSG00000176845 | OMIM ID: 616241 |
| Drug and gene relationship at DGIdb | |||
Expression of METRNL:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | METRNL | 284207 | 225955_at | -1.0049 | 0.3292 | |
| GSE26886 | METRNL | 284207 | 225955_at | -1.5360 | 0.0001 | |
| GSE45670 | METRNL | 284207 | 225955_at | -0.3640 | 0.1428 | |
| GSE53622 | METRNL | 284207 | 147517 | -1.2759 | 0.0000 | |
| GSE53624 | METRNL | 284207 | 147517 | -1.3610 | 0.0000 | |
| GSE63941 | METRNL | 284207 | 225955_at | -1.6948 | 0.0314 | |
| GSE77861 | METRNL | 284207 | 225955_at | -0.8158 | 0.0784 | |
| GSE97050 | METRNL | 284207 | A_23_P10591 | -0.0804 | 0.8408 | |
| SRP007169 | METRNL | 284207 | RNAseq | -3.4317 | 0.0000 | |
| SRP008496 | METRNL | 284207 | RNAseq | -2.9130 | 0.0000 | |
| SRP064894 | METRNL | 284207 | RNAseq | -0.8573 | 0.0062 | |
| SRP133303 | METRNL | 284207 | RNAseq | -1.1171 | 0.0000 | |
| SRP159526 | METRNL | 284207 | RNAseq | -2.1490 | 0.0000 | |
| SRP193095 | METRNL | 284207 | RNAseq | -1.5662 | 0.0000 | |
| SRP219564 | METRNL | 284207 | RNAseq | -0.9691 | 0.0412 | |
| TCGA | METRNL | 284207 | RNAseq | -0.0409 | 0.7065 |
Upregulated datasets: 0; Downregulated datasets: 9.
Survival by METRNL expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of METRNL:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | METRNL | 284207 | 4 | 5 | 21 | |
| GSE20123 | METRNL | 284207 | 4 | 5 | 21 | |
| GSE43470 | METRNL | 284207 | 3 | 5 | 35 | |
| GSE46452 | METRNL | 284207 | 34 | 0 | 25 | |
| GSE47630 | METRNL | 284207 | 9 | 2 | 29 | |
| GSE54993 | METRNL | 284207 | 2 | 5 | 63 | |
| GSE54994 | METRNL | 284207 | 10 | 6 | 37 | |
| GSE60625 | METRNL | 284207 | 6 | 0 | 5 | |
| GSE74703 | METRNL | 284207 | 3 | 3 | 30 | |
| GSE74704 | METRNL | 284207 | 4 | 4 | 12 | |
| TCGA | METRNL | 284207 | 24 | 14 | 58 |
Total number of gains: 103; Total number of losses: 49; Total Number of normals: 336.
Somatic mutations of METRNL:
Generating mutation plots.
Highly correlated genes for METRNL:
Showing top 20/1128 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| METRNL | MXD1 | 0.793047 | 7 | 0 | 7 |
| METRNL | PIM1 | 0.792016 | 7 | 0 | 7 |
| METRNL | SBSN | 0.78158 | 7 | 0 | 6 |
| METRNL | CYSRT1 | 0.769554 | 6 | 0 | 6 |
| METRNL | MALL | 0.768366 | 6 | 0 | 6 |
| METRNL | VSIG10L | 0.766667 | 6 | 0 | 6 |
| METRNL | ATG13 | 0.764749 | 3 | 0 | 3 |
| METRNL | SH3GL1 | 0.764106 | 7 | 0 | 7 |
| METRNL | ECM1 | 0.75459 | 7 | 0 | 7 |
| METRNL | SPNS2 | 0.754039 | 5 | 0 | 5 |
| METRNL | LYNX1 | 0.752117 | 6 | 0 | 6 |
| METRNL | TOM1 | 0.751337 | 8 | 0 | 7 |
| METRNL | SMIM5 | 0.748495 | 6 | 0 | 6 |
| METRNL | IL20RB | 0.74646 | 6 | 0 | 6 |
| METRNL | TMPRSS11E | 0.745701 | 6 | 0 | 6 |
| METRNL | CRCT1 | 0.736868 | 7 | 0 | 6 |
| METRNL | SLPI | 0.736573 | 7 | 0 | 6 |
| METRNL | PLIN3 | 0.734287 | 8 | 0 | 7 |
| METRNL | RAD21L1 | 0.731757 | 3 | 0 | 3 |
| METRNL | STRN | 0.731631 | 7 | 0 | 7 |
For details and further investigation, click here
