| Full name: ATPase Na+/K+ transporting subunit alpha 3 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 19q13.2 | ||
| Entrez ID: 478 | HGNC ID: HGNC:801 | Ensembl Gene: ENSG00000105409 | OMIM ID: 182350 |
| Drug and gene relationship at DGIdb | |||
ATP1A3 involved pathways:
Expression of ATP1A3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ATP1A3 | 478 | 214432_at | 0.0288 | 0.9229 | |
| GSE20347 | ATP1A3 | 478 | 214432_at | -0.1218 | 0.0751 | |
| GSE23400 | ATP1A3 | 478 | 214432_at | -0.1788 | 0.0001 | |
| GSE26886 | ATP1A3 | 478 | 214432_at | 0.3178 | 0.0470 | |
| GSE29001 | ATP1A3 | 478 | 214432_at | -0.1614 | 0.2704 | |
| GSE38129 | ATP1A3 | 478 | 214432_at | -0.1171 | 0.1669 | |
| GSE45670 | ATP1A3 | 478 | 214432_at | -0.0933 | 0.4034 | |
| GSE53622 | ATP1A3 | 478 | 66056 | -0.0131 | 0.9096 | |
| GSE53624 | ATP1A3 | 478 | 66056 | 0.2984 | 0.0000 | |
| GSE63941 | ATP1A3 | 478 | 214432_at | 0.5069 | 0.0305 | |
| GSE77861 | ATP1A3 | 478 | 214432_at | -0.1505 | 0.2211 | |
| GSE97050 | ATP1A3 | 478 | A_33_P3283669 | 0.0816 | 0.6767 | |
| SRP159526 | ATP1A3 | 478 | RNAseq | 0.8883 | 0.3684 | |
| TCGA | ATP1A3 | 478 | RNAseq | -0.6407 | 0.1130 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by ATP1A3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ATP1A3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ATP1A3 | 478 | 4 | 4 | 22 | |
| GSE20123 | ATP1A3 | 478 | 4 | 3 | 23 | |
| GSE43470 | ATP1A3 | 478 | 3 | 11 | 29 | |
| GSE46452 | ATP1A3 | 478 | 47 | 1 | 11 | |
| GSE47630 | ATP1A3 | 478 | 8 | 6 | 26 | |
| GSE54993 | ATP1A3 | 478 | 17 | 4 | 49 | |
| GSE54994 | ATP1A3 | 478 | 7 | 12 | 34 | |
| GSE60625 | ATP1A3 | 478 | 9 | 0 | 2 | |
| GSE74703 | ATP1A3 | 478 | 3 | 7 | 26 | |
| GSE74704 | ATP1A3 | 478 | 4 | 1 | 15 | |
| TCGA | ATP1A3 | 478 | 14 | 15 | 67 |
Total number of gains: 120; Total number of losses: 64; Total Number of normals: 304.
Somatic mutations of ATP1A3:
Generating mutation plots.
Highly correlated genes for ATP1A3:
Showing top 20/581 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ATP1A3 | MAP1LC3B2 | 0.749787 | 3 | 0 | 3 |
| ATP1A3 | GGN | 0.687082 | 4 | 0 | 4 |
| ATP1A3 | PLIN4 | 0.683725 | 3 | 0 | 3 |
| ATP1A3 | NSMF | 0.678967 | 3 | 0 | 3 |
| ATP1A3 | DIS3L2 | 0.678526 | 3 | 0 | 3 |
| ATP1A3 | LINC01136 | 0.671445 | 3 | 0 | 3 |
| ATP1A3 | RHAG | 0.669985 | 6 | 0 | 6 |
| ATP1A3 | MIOX | 0.669375 | 4 | 0 | 3 |
| ATP1A3 | CNTF | 0.661746 | 3 | 0 | 3 |
| ATP1A3 | SMTNL2 | 0.659374 | 3 | 0 | 3 |
| ATP1A3 | KRT76 | 0.658389 | 4 | 0 | 4 |
| ATP1A3 | ZNF414 | 0.654925 | 3 | 0 | 3 |
| ATP1A3 | SFMBT1 | 0.652495 | 4 | 0 | 3 |
| ATP1A3 | SHOX | 0.652463 | 4 | 0 | 4 |
| ATP1A3 | TMPRSS6 | 0.650647 | 4 | 0 | 3 |
| ATP1A3 | TSSK2 | 0.648238 | 5 | 0 | 4 |
| ATP1A3 | GCNT4 | 0.645123 | 3 | 0 | 3 |
| ATP1A3 | CA8 | 0.642134 | 4 | 0 | 3 |
| ATP1A3 | ATG10 | 0.642052 | 5 | 0 | 4 |
| ATP1A3 | GNG3 | 0.641654 | 4 | 0 | 4 |
For details and further investigation, click here
