THTPA

 

Full name: thiamine triphosphatase Alias Symbol: THTPASE
Type: protein-coding gene Cytoband: 14q11.2
Entrez ID: 79178 HGNC ID: HGNC:18987 Ensembl Gene: ENSG00000259431 OMIM ID: 611612
Drug and gene relationship at DGIdb

 

Expression of THTPA:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 THTPA 79178 218540_at -0.3176 0.3905
GSE20347 THTPA 79178 218540_at -0.0215 0.9162
GSE23400 THTPA 79178 218540_at 0.0721 0.2321
GSE26886 THTPA 79178 218540_at -0.3778 0.1014
GSE29001 THTPA 79178 218540_at 0.0259 0.8936
GSE38129 THTPA 79178 218540_at -0.2703 0.0517
GSE45670 THTPA 79178 218540_at 0.0772 0.7566
GSE63941 THTPA 79178 218540_at 0.6374 0.3185
GSE77861 THTPA 79178 218540_at 0.0451 0.7315
GSE97050 THTPA 79178 A_23_P54041 0.0169 0.9539
SRP007169 THTPA 79178 RNAseq 1.2969 0.1607
SRP064894 THTPA 79178 RNAseq 0.1577 0.5410
SRP133303 THTPA 79178 RNAseq -0.2400 0.2549
SRP159526 THTPA 79178 RNAseq 0.4087 0.1716
SRP193095 THTPA 79178 RNAseq 0.0933 0.4787
SRP219564 THTPA 79178 RNAseq -0.7136 0.1410
TCGA THTPA 79178 RNAseq -0.1909 0.0142

Upregulated datasets: 0; Downregulated datasets: 0.  

 

Survival by THTPA expression:

 

TCGA

 

Note: Click image to view full size file.  

Copy number change of THTPA:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 THTPA 79178 8 1 21
GSE20123 THTPA 79178 8 1 21
GSE43470 THTPA 79178 7 2 34
GSE46452 THTPA 79178 17 2 40
GSE47630 THTPA 79178 11 10 19
GSE54993 THTPA 79178 3 11 56
GSE54994 THTPA 79178 18 5 30
GSE60625 THTPA 79178 0 2 9
GSE74703 THTPA 79178 6 2 28
GSE74704 THTPA 79178 3 1 16
TCGA THTPA 79178 27 14 55

Total number of gains: 108; Total number of losses: 51; Total Number of normals: 329.  

 

Somatic mutations of THTPA:

 

Generating mutation plots.

 

Highly correlated genes for THTPA:

 

Showing all 8 correlated genes with mean PCC>0.5.

Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
THTPASDR39U10.591289503
THTPAPPP1R3E0.569072403
THTPADAD10.548103604
THTPAVEGFB0.532353303
THTPASPOP0.522398503
THTPAPABPN10.516088703
THTPARBM230.512766904
THTPABCL2L20.502501703

For details and further investigation, click here