| Full name: BCL2 like 2 | Alias Symbol: KIAA0271|BCL-W|PPP1R51 | ||
| Type: protein-coding gene | Cytoband: 14q11.2 | ||
| Entrez ID: 599 | HGNC ID: HGNC:995 | Ensembl Gene: ENSG00000129473 | OMIM ID: 601931 |
| Drug and gene relationship at DGIdb | |||
Expression of BCL2L2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | BCL2L2 | 599 | 209311_at | -0.3606 | 0.6027 | |
| GSE20347 | BCL2L2 | 599 | 209311_at | -0.6106 | 0.0002 | |
| GSE23400 | BCL2L2 | 599 | 209311_at | -0.2810 | 0.0001 | |
| GSE26886 | BCL2L2 | 599 | 209311_at | -1.5129 | 0.0000 | |
| GSE29001 | BCL2L2 | 599 | 209311_at | -0.0472 | 0.8897 | |
| GSE38129 | BCL2L2 | 599 | 209311_at | -0.6918 | 0.0000 | |
| GSE45670 | BCL2L2 | 599 | 209311_at | -0.1877 | 0.2305 | |
| GSE53622 | BCL2L2 | 599 | 108998 | -0.5428 | 0.0000 | |
| GSE53624 | BCL2L2 | 599 | 108998 | -0.6001 | 0.0000 | |
| GSE63941 | BCL2L2 | 599 | 209311_at | -0.4063 | 0.4427 | |
| GSE77861 | BCL2L2 | 599 | 209311_at | -0.1359 | 0.7422 | |
| GSE97050 | BCL2L2 | 599 | A_23_P418373 | -0.4131 | 0.2465 | |
| SRP007169 | BCL2L2 | 599 | RNAseq | -0.6458 | 0.0934 | |
| SRP008496 | BCL2L2 | 599 | RNAseq | -0.6625 | 0.0126 | |
| SRP064894 | BCL2L2 | 599 | RNAseq | -0.2442 | 0.1915 | |
| SRP133303 | BCL2L2 | 599 | RNAseq | -0.1866 | 0.4297 | |
| SRP159526 | BCL2L2 | 599 | RNAseq | -0.5972 | 0.0794 | |
| SRP193095 | BCL2L2 | 599 | RNAseq | -0.4134 | 0.0051 | |
| SRP219564 | BCL2L2 | 599 | RNAseq | -0.7235 | 0.0184 | |
| TCGA | BCL2L2 | 599 | RNAseq | -0.2788 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by BCL2L2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of BCL2L2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | BCL2L2 | 599 | 9 | 1 | 20 | |
| GSE20123 | BCL2L2 | 599 | 9 | 1 | 20 | |
| GSE43470 | BCL2L2 | 599 | 7 | 2 | 34 | |
| GSE46452 | BCL2L2 | 599 | 17 | 2 | 40 | |
| GSE47630 | BCL2L2 | 599 | 11 | 10 | 19 | |
| GSE54993 | BCL2L2 | 599 | 3 | 11 | 56 | |
| GSE54994 | BCL2L2 | 599 | 18 | 5 | 30 | |
| GSE60625 | BCL2L2 | 599 | 0 | 2 | 9 | |
| GSE74703 | BCL2L2 | 599 | 6 | 2 | 28 | |
| GSE74704 | BCL2L2 | 599 | 4 | 1 | 15 | |
| TCGA | BCL2L2 | 599 | 27 | 14 | 55 |
Total number of gains: 111; Total number of losses: 51; Total Number of normals: 326.
Somatic mutations of BCL2L2:
Generating mutation plots.
Highly correlated genes for BCL2L2:
Showing top 20/319 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| BCL2L2 | HDAC3 | 0.725791 | 3 | 0 | 3 |
| BCL2L2 | ARFGEF2 | 0.679697 | 3 | 0 | 3 |
| BCL2L2 | PRPSAP1 | 0.658983 | 3 | 0 | 3 |
| BCL2L2 | C5orf24 | 0.647943 | 3 | 0 | 3 |
| BCL2L2 | RTN3 | 0.638382 | 3 | 0 | 3 |
| BCL2L2 | BTD | 0.637758 | 4 | 0 | 4 |
| BCL2L2 | NDUFV2-AS1 | 0.632901 | 3 | 0 | 3 |
| BCL2L2 | MOB2 | 0.628949 | 4 | 0 | 3 |
| BCL2L2 | NKIRAS1 | 0.626 | 5 | 0 | 4 |
| BCL2L2 | TTC39A | 0.625752 | 3 | 0 | 3 |
| BCL2L2 | OSBPL2 | 0.62354 | 5 | 0 | 4 |
| BCL2L2 | ATP6V1G1 | 0.621308 | 3 | 0 | 3 |
| BCL2L2 | GSN | 0.621239 | 8 | 0 | 7 |
| BCL2L2 | RBM8A | 0.619705 | 4 | 0 | 3 |
| BCL2L2 | TCAIM | 0.617564 | 3 | 0 | 3 |
| BCL2L2 | VTI1B | 0.616249 | 6 | 0 | 5 |
| BCL2L2 | SDHC | 0.614818 | 4 | 0 | 3 |
| BCL2L2 | KIAA0232 | 0.613522 | 8 | 0 | 5 |
| BCL2L2 | CGGBP1 | 0.61137 | 4 | 0 | 3 |
| BCL2L2 | SNX9 | 0.610565 | 4 | 0 | 4 |
For details and further investigation, click here
