| Full name: short chain dehydrogenase/reductase family 39U member 1 | Alias Symbol: HCDI | ||
| Type: protein-coding gene | Cytoband: 14q12 | ||
| Entrez ID: 56948 | HGNC ID: HGNC:20275 | Ensembl Gene: ENSG00000100445 | OMIM ID: 616162 |
| Drug and gene relationship at DGIdb | |||
Expression of SDR39U1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SDR39U1 | 56948 | 213398_s_at | -0.1123 | 0.8046 | |
| GSE20347 | SDR39U1 | 56948 | 213398_s_at | 0.3001 | 0.0775 | |
| GSE23400 | SDR39U1 | 56948 | 213398_s_at | 0.1772 | 0.0214 | |
| GSE26886 | SDR39U1 | 56948 | 213398_s_at | 0.9148 | 0.0000 | |
| GSE29001 | SDR39U1 | 56948 | 213398_s_at | 0.3141 | 0.0825 | |
| GSE38129 | SDR39U1 | 56948 | 213398_s_at | 0.0148 | 0.9296 | |
| GSE45670 | SDR39U1 | 56948 | 213398_s_at | -0.0287 | 0.8864 | |
| GSE63941 | SDR39U1 | 56948 | 213398_s_at | 0.1831 | 0.7818 | |
| GSE77861 | SDR39U1 | 56948 | 213398_s_at | 0.1838 | 0.5527 | |
| GSE97050 | SDR39U1 | 56948 | A_23_P163161 | 0.1518 | 0.4648 | |
| SRP007169 | SDR39U1 | 56948 | RNAseq | 0.4970 | 0.3062 | |
| SRP008496 | SDR39U1 | 56948 | RNAseq | -0.2961 | 0.4296 | |
| SRP064894 | SDR39U1 | 56948 | RNAseq | 0.4133 | 0.0569 | |
| SRP133303 | SDR39U1 | 56948 | RNAseq | -0.3554 | 0.0778 | |
| SRP159526 | SDR39U1 | 56948 | RNAseq | 0.4755 | 0.1462 | |
| SRP193095 | SDR39U1 | 56948 | RNAseq | 0.1140 | 0.4423 | |
| SRP219564 | SDR39U1 | 56948 | RNAseq | 0.0373 | 0.9358 | |
| TCGA | SDR39U1 | 56948 | RNAseq | -0.0798 | 0.1999 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by SDR39U1 expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of SDR39U1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SDR39U1 | 56948 | 8 | 3 | 19 | |
| GSE20123 | SDR39U1 | 56948 | 8 | 3 | 19 | |
| GSE43470 | SDR39U1 | 56948 | 8 | 2 | 33 | |
| GSE46452 | SDR39U1 | 56948 | 16 | 2 | 41 | |
| GSE47630 | SDR39U1 | 56948 | 11 | 10 | 19 | |
| GSE54993 | SDR39U1 | 56948 | 3 | 11 | 56 | |
| GSE54994 | SDR39U1 | 56948 | 18 | 5 | 30 | |
| GSE60625 | SDR39U1 | 56948 | 0 | 2 | 9 | |
| GSE74703 | SDR39U1 | 56948 | 7 | 2 | 27 | |
| GSE74704 | SDR39U1 | 56948 | 3 | 2 | 15 | |
| TCGA | SDR39U1 | 56948 | 28 | 12 | 56 |
Total number of gains: 110; Total number of losses: 54; Total Number of normals: 324.
Somatic mutations of SDR39U1:
Generating mutation plots.
Highly correlated genes for SDR39U1:
Showing top 20/223 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SDR39U1 | ARHGAP24 | 0.802009 | 3 | 0 | 3 |
| SDR39U1 | MYO3B | 0.785305 | 3 | 0 | 3 |
| SDR39U1 | MYOF | 0.780727 | 3 | 0 | 3 |
| SDR39U1 | ASXL2 | 0.780328 | 3 | 0 | 3 |
| SDR39U1 | INVS | 0.769701 | 3 | 0 | 3 |
| SDR39U1 | TPCN2 | 0.766331 | 3 | 0 | 3 |
| SDR39U1 | ZNF827 | 0.765348 | 3 | 0 | 3 |
| SDR39U1 | HMGN3 | 0.759228 | 3 | 0 | 3 |
| SDR39U1 | RFX7 | 0.752702 | 3 | 0 | 3 |
| SDR39U1 | CIC | 0.749527 | 3 | 0 | 3 |
| SDR39U1 | ITGA3 | 0.747981 | 3 | 0 | 3 |
| SDR39U1 | FAM86C1 | 0.745754 | 3 | 0 | 3 |
| SDR39U1 | ADAR | 0.745316 | 3 | 0 | 3 |
| SDR39U1 | MYC | 0.739283 | 3 | 0 | 3 |
| SDR39U1 | APOO | 0.73833 | 3 | 0 | 3 |
| SDR39U1 | CDKN1C | 0.733849 | 3 | 0 | 3 |
| SDR39U1 | GNB5 | 0.733726 | 3 | 0 | 3 |
| SDR39U1 | CD44 | 0.733255 | 3 | 0 | 3 |
| SDR39U1 | SNRPF | 0.730663 | 3 | 0 | 3 |
| SDR39U1 | ACY1 | 0.729689 | 3 | 0 | 3 |
For details and further investigation, click here
