| Full name: vascular endothelial growth factor B | Alias Symbol: VEGFL | ||
| Type: protein-coding gene | Cytoband: 11q13.1 | ||
| Entrez ID: 7423 | HGNC ID: HGNC:12681 | Ensembl Gene: ENSG00000173511 | OMIM ID: 601398 |
| Drug and gene relationship at DGIdb | |||
VEGFB involved pathways:
Expression of VEGFB:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | VEGFB | 7423 | 203683_s_at | 0.3401 | 0.5566 | |
| GSE20347 | VEGFB | 7423 | 203683_s_at | 0.3156 | 0.0678 | |
| GSE23400 | VEGFB | 7423 | 203683_s_at | 0.1924 | 0.0488 | |
| GSE26886 | VEGFB | 7423 | 203683_s_at | 0.4571 | 0.0050 | |
| GSE29001 | VEGFB | 7423 | 203683_s_at | 0.1268 | 0.3426 | |
| GSE38129 | VEGFB | 7423 | 203683_s_at | -0.0015 | 0.9947 | |
| GSE45670 | VEGFB | 7423 | 203683_s_at | -0.0355 | 0.8405 | |
| GSE53622 | VEGFB | 7423 | 53025 | 0.0934 | 0.3206 | |
| GSE53624 | VEGFB | 7423 | 53025 | 0.3166 | 0.0000 | |
| GSE63941 | VEGFB | 7423 | 203683_s_at | 0.1820 | 0.6791 | |
| GSE77861 | VEGFB | 7423 | 203683_s_at | 0.1280 | 0.5736 | |
| GSE97050 | VEGFB | 7423 | A_23_P1594 | -0.4012 | 0.2575 | |
| SRP007169 | VEGFB | 7423 | RNAseq | 0.6769 | 0.2411 | |
| SRP008496 | VEGFB | 7423 | RNAseq | 0.1148 | 0.7867 | |
| SRP064894 | VEGFB | 7423 | RNAseq | 0.2188 | 0.4155 | |
| SRP133303 | VEGFB | 7423 | RNAseq | 0.1259 | 0.5383 | |
| SRP159526 | VEGFB | 7423 | RNAseq | 0.2502 | 0.2303 | |
| SRP193095 | VEGFB | 7423 | RNAseq | 0.3447 | 0.0139 | |
| SRP219564 | VEGFB | 7423 | RNAseq | -0.2065 | 0.7204 | |
| TCGA | VEGFB | 7423 | RNAseq | -0.1641 | 0.0005 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by VEGFB expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of VEGFB:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | VEGFB | 7423 | 6 | 5 | 19 | |
| GSE20123 | VEGFB | 7423 | 6 | 5 | 19 | |
| GSE43470 | VEGFB | 7423 | 1 | 3 | 39 | |
| GSE46452 | VEGFB | 7423 | 8 | 4 | 47 | |
| GSE47630 | VEGFB | 7423 | 4 | 6 | 30 | |
| GSE54993 | VEGFB | 7423 | 3 | 0 | 67 | |
| GSE54994 | VEGFB | 7423 | 5 | 5 | 43 | |
| GSE60625 | VEGFB | 7423 | 0 | 4 | 7 | |
| GSE74703 | VEGFB | 7423 | 1 | 1 | 34 | |
| GSE74704 | VEGFB | 7423 | 4 | 3 | 13 | |
| TCGA | VEGFB | 7423 | 19 | 10 | 67 |
Total number of gains: 57; Total number of losses: 46; Total Number of normals: 385.
Somatic mutations of VEGFB:
Generating mutation plots.
Highly correlated genes for VEGFB:
Showing top 20/624 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| VEGFB | RPRD2 | 0.807543 | 3 | 0 | 3 |
| VEGFB | SLC39A3 | 0.746862 | 3 | 0 | 3 |
| VEGFB | SHANK3 | 0.735754 | 3 | 0 | 3 |
| VEGFB | MCOLN3 | 0.733532 | 3 | 0 | 3 |
| VEGFB | UCN | 0.731497 | 3 | 0 | 3 |
| VEGFB | FUNDC2 | 0.727825 | 3 | 0 | 3 |
| VEGFB | IGF2R | 0.727799 | 3 | 0 | 3 |
| VEGFB | CD34 | 0.722359 | 3 | 0 | 3 |
| VEGFB | KRTCAP2 | 0.721613 | 4 | 0 | 4 |
| VEGFB | KHNYN | 0.721242 | 3 | 0 | 3 |
| VEGFB | PSMC4 | 0.718672 | 3 | 0 | 3 |
| VEGFB | NAALAD2 | 0.71706 | 3 | 0 | 3 |
| VEGFB | NAP1L4 | 0.713594 | 3 | 0 | 3 |
| VEGFB | REC8 | 0.711147 | 3 | 0 | 3 |
| VEGFB | DVL3 | 0.710043 | 3 | 0 | 3 |
| VEGFB | SLC46A1 | 0.709792 | 3 | 0 | 3 |
| VEGFB | PRELP | 0.709789 | 3 | 0 | 3 |
| VEGFB | GPS2 | 0.708718 | 3 | 0 | 3 |
| VEGFB | PECAM1 | 0.705769 | 3 | 0 | 3 |
| VEGFB | PFDN2 | 0.701895 | 3 | 0 | 3 |
For details and further investigation, click here
