| Full name: zinc finger protein 546 | Alias Symbol: MGC43537 | ||
| Type: protein-coding gene | Cytoband: 19q13.2 | ||
| Entrez ID: 339327 | HGNC ID: HGNC:28671 | Ensembl Gene: ENSG00000187187 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of ZNF546:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ZNF546 | 339327 | 240429_at | -0.3364 | 0.1496 | |
| GSE26886 | ZNF546 | 339327 | 240429_at | -0.1076 | 0.2733 | |
| GSE45670 | ZNF546 | 339327 | 240429_at | -0.1588 | 0.2786 | |
| GSE53622 | ZNF546 | 339327 | 45445 | 0.3633 | 0.0061 | |
| GSE53624 | ZNF546 | 339327 | 45445 | 0.2120 | 0.1251 | |
| GSE97050 | ZNF546 | 339327 | A_33_P3267740 | 0.0457 | 0.8394 | |
| SRP007169 | ZNF546 | 339327 | RNAseq | 0.6405 | 0.2908 | |
| SRP064894 | ZNF546 | 339327 | RNAseq | -0.0970 | 0.6728 | |
| SRP133303 | ZNF546 | 339327 | RNAseq | -0.1670 | 0.2444 | |
| SRP159526 | ZNF546 | 339327 | RNAseq | 0.0846 | 0.7785 | |
| SRP193095 | ZNF546 | 339327 | RNAseq | -0.0743 | 0.5727 | |
| SRP219564 | ZNF546 | 339327 | RNAseq | -0.1158 | 0.7041 | |
| TCGA | ZNF546 | 339327 | RNAseq | -0.5813 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by ZNF546 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ZNF546:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ZNF546 | 339327 | 7 | 4 | 19 | |
| GSE20123 | ZNF546 | 339327 | 7 | 3 | 20 | |
| GSE43470 | ZNF546 | 339327 | 3 | 9 | 31 | |
| GSE46452 | ZNF546 | 339327 | 48 | 1 | 10 | |
| GSE47630 | ZNF546 | 339327 | 9 | 5 | 26 | |
| GSE54993 | ZNF546 | 339327 | 17 | 3 | 50 | |
| GSE54994 | ZNF546 | 339327 | 8 | 9 | 36 | |
| GSE60625 | ZNF546 | 339327 | 9 | 0 | 2 | |
| GSE74703 | ZNF546 | 339327 | 3 | 6 | 27 | |
| GSE74704 | ZNF546 | 339327 | 7 | 1 | 12 | |
| TCGA | ZNF546 | 339327 | 14 | 16 | 66 |
Total number of gains: 132; Total number of losses: 57; Total Number of normals: 299.
Somatic mutations of ZNF546:
Generating mutation plots.
Highly correlated genes for ZNF546:
Showing top 20/153 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ZNF546 | ZNF583 | 0.900792 | 3 | 0 | 3 |
| ZNF546 | ZNF878 | 0.892614 | 3 | 0 | 3 |
| ZNF546 | ZNF547 | 0.851426 | 3 | 0 | 3 |
| ZNF546 | ZNF595 | 0.821967 | 3 | 0 | 3 |
| ZNF546 | ZNF225 | 0.80885 | 4 | 0 | 4 |
| ZNF546 | ZNF638 | 0.802574 | 3 | 0 | 3 |
| ZNF546 | ZNF676 | 0.800864 | 3 | 0 | 3 |
| ZNF546 | ZNF735 | 0.79529 | 3 | 0 | 3 |
| ZNF546 | ZNF816 | 0.793293 | 3 | 0 | 3 |
| ZNF546 | PIGP | 0.790211 | 3 | 0 | 3 |
| ZNF546 | ZNF345 | 0.782328 | 3 | 0 | 3 |
| ZNF546 | CRIM1 | 0.775114 | 3 | 0 | 3 |
| ZNF546 | ZNF461 | 0.773943 | 4 | 0 | 3 |
| ZNF546 | DUSP3 | 0.771267 | 3 | 0 | 3 |
| ZNF546 | ZNF585A | 0.76941 | 3 | 0 | 3 |
| ZNF546 | ARHGEF33 | 0.765415 | 4 | 0 | 4 |
| ZNF546 | TSPAN3 | 0.750182 | 3 | 0 | 3 |
| ZNF546 | ZMAT1 | 0.746986 | 3 | 0 | 3 |
| ZNF546 | PRKACB | 0.745216 | 3 | 0 | 3 |
| ZNF546 | APOB | 0.744459 | 4 | 0 | 4 |
For details and further investigation, click here
