| Full name: cysteine rich transmembrane BMP regulator 1 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 2p22.2 | ||
| Entrez ID: 51232 | HGNC ID: HGNC:2359 | Ensembl Gene: ENSG00000150938 | OMIM ID: 606189 |
| Drug and gene relationship at DGIdb | |||
Expression of CRIM1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CRIM1 | 51232 | 202551_s_at | -0.9260 | 0.1731 | |
| GSE20347 | CRIM1 | 51232 | 202551_s_at | -0.4509 | 0.0876 | |
| GSE23400 | CRIM1 | 51232 | 202551_s_at | -0.2343 | 0.0886 | |
| GSE26886 | CRIM1 | 51232 | 228496_s_at | -0.3212 | 0.1843 | |
| GSE29001 | CRIM1 | 51232 | 202552_s_at | -0.1377 | 0.7666 | |
| GSE38129 | CRIM1 | 51232 | 202551_s_at | -0.6557 | 0.0097 | |
| GSE45670 | CRIM1 | 51232 | 202551_s_at | -0.9591 | 0.0013 | |
| GSE53622 | CRIM1 | 51232 | 119534 | -0.4332 | 0.0002 | |
| GSE53624 | CRIM1 | 51232 | 119534 | -0.3113 | 0.0258 | |
| GSE63941 | CRIM1 | 51232 | 228496_s_at | -0.9085 | 0.3174 | |
| GSE77861 | CRIM1 | 51232 | 228496_s_at | 0.4263 | 0.3559 | |
| GSE97050 | CRIM1 | 51232 | A_24_P11575 | -0.4797 | 0.1506 | |
| SRP007169 | CRIM1 | 51232 | RNAseq | 0.9321 | 0.0414 | |
| SRP008496 | CRIM1 | 51232 | RNAseq | 1.1418 | 0.0000 | |
| SRP064894 | CRIM1 | 51232 | RNAseq | -0.1958 | 0.5374 | |
| SRP133303 | CRIM1 | 51232 | RNAseq | -0.2842 | 0.1817 | |
| SRP159526 | CRIM1 | 51232 | RNAseq | 0.0021 | 0.9946 | |
| SRP193095 | CRIM1 | 51232 | RNAseq | 0.4977 | 0.0005 | |
| SRP219564 | CRIM1 | 51232 | RNAseq | -0.4626 | 0.4615 | |
| TCGA | CRIM1 | 51232 | RNAseq | -0.1555 | 0.0314 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by CRIM1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CRIM1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CRIM1 | 51232 | 10 | 1 | 19 | |
| GSE20123 | CRIM1 | 51232 | 8 | 1 | 21 | |
| GSE43470 | CRIM1 | 51232 | 3 | 0 | 40 | |
| GSE46452 | CRIM1 | 51232 | 2 | 4 | 53 | |
| GSE47630 | CRIM1 | 51232 | 7 | 0 | 33 | |
| GSE54993 | CRIM1 | 51232 | 0 | 5 | 65 | |
| GSE54994 | CRIM1 | 51232 | 10 | 0 | 43 | |
| GSE60625 | CRIM1 | 51232 | 0 | 3 | 8 | |
| GSE74703 | CRIM1 | 51232 | 3 | 0 | 33 | |
| GSE74704 | CRIM1 | 51232 | 8 | 1 | 11 | |
| TCGA | CRIM1 | 51232 | 35 | 3 | 58 |
Total number of gains: 86; Total number of losses: 18; Total Number of normals: 384.
Somatic mutations of CRIM1:
Generating mutation plots.
Highly correlated genes for CRIM1:
Showing top 20/554 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CRIM1 | SRPX | 0.782293 | 5 | 0 | 5 |
| CRIM1 | ZNF546 | 0.775114 | 3 | 0 | 3 |
| CRIM1 | SBF2 | 0.762833 | 3 | 0 | 3 |
| CRIM1 | YAP1 | 0.761955 | 3 | 0 | 3 |
| CRIM1 | IREB2 | 0.760866 | 3 | 0 | 3 |
| CRIM1 | FOXN3 | 0.74646 | 3 | 0 | 3 |
| CRIM1 | KBTBD2 | 0.744784 | 3 | 0 | 3 |
| CRIM1 | TGFB1I1 | 0.744535 | 5 | 0 | 5 |
| CRIM1 | LRCH2 | 0.73874 | 4 | 0 | 4 |
| CRIM1 | STYX | 0.732972 | 3 | 0 | 3 |
| CRIM1 | CWF19L2 | 0.732112 | 3 | 0 | 3 |
| CRIM1 | C11orf96 | 0.727868 | 3 | 0 | 3 |
| CRIM1 | COX15 | 0.724209 | 3 | 0 | 3 |
| CRIM1 | SPA17 | 0.722726 | 3 | 0 | 3 |
| CRIM1 | SEC11A | 0.721159 | 3 | 0 | 3 |
| CRIM1 | CFL2 | 0.716645 | 4 | 0 | 4 |
| CRIM1 | PPP3CC | 0.715988 | 3 | 0 | 3 |
| CRIM1 | CCNC | 0.714855 | 3 | 0 | 3 |
| CRIM1 | BIRC2 | 0.712889 | 3 | 0 | 3 |
| CRIM1 | CYS1 | 0.711063 | 4 | 0 | 4 |
For details and further investigation, click here
